Crystallisation and Structure Determination Publications

  1. , Graslund S., Peleg Y., Albeck S., Unger T., Dym O., Prilusky J. & Sussman J. L. (2008). Protein production and purification.  Nature Methods. 2008 Feb , 5 (2):135-146.
  2. Dym O., Albeck S., Unger T., Jacobovitch J., Brainzburg A., Michael Y., Frenkiel-Krispin D., Wolf S. G. & Elbaum M. (2008). Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.  Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug , 105 (32):11170-11175.
  3. Cohen S., Dym O., Albeck S., Ben-Dov E., Cahan R., Firer M. & Zaritsky A. (2008). High-resolution crystal structure of activated Cyt2Ba monomer from Bacillus thuringiensis subsp israelensis.  Journal of Molecular Biology. 2008 Jul , 380 (5):820-827.
  4. Shaaltiel Y., Bartfeld D., Hashmueli S., Baum G., Brill-Almon E., Galili G., Dym O., Boldin-Adamsky S. A., Silman I., Sussman J., Futerman A. H. & Aviezer D. (2007). Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.  Plant Biotechnology Journal. 2007 Sept , 5 (5):579-590.
  5. Reichmann D., Cohen M., Abramovich R., Dym O., Lim D., Strynadka N. C. J. & Schreiber G. (2007). Binding hot spots in the TEM1-BLIP interface in light of its modular architecture.  Journal of Molecular Biology. 2007 Jan , 365 (3):663-679.
  6. Goihberg E., Dym O., Tel-Or S., Levin I., Peretz M. & Burstein Y. (2007). A single proline substitution is critical for the thermostabilization of Clostridium beijerinckii alcohol dehydrogenase.  Proteins-Structure Function And Bioinformatics. 2007 Jan , 66 (1):196-204.
  7. Asher G., Dym O., Tsvetkov P., Adler J. & Shaul Y. (2006). The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.  Biochemistry. 2006 May , 45 (20):6372-6378.
  8. Berry I. M., Dym O., Esnouf R. M., Harlos K., Meged R., Perrakis A., Sussman J., Walter T. S., Wilson J. & Messerschmidt A. (2006). Spine High-Throughput Crystallization, Crystal Imaging And Recognition Techniques: Current State, Performance Analysis, New Technologies And Future Aspects.  Acta Crystallographica Section D-Biological Crystallography. 2006 Oct , 62 :1137-1149.
  9. Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. -., Burmeister W. P., Cambillau C., Canard B., Carrondo M., Coll M., Daenke S., Dym O., Egloff M. -., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q. & Manicka S. N. (2006). Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.  Acta Crystallographica Section D-Biological Crystallography. 2006 Oct , 62 :1196-1207.
  10. Albeck S., Alzari P., Andreini C., Banci L., Berry I. M., Bertini I., Cambillau C., Canard B., Carter L., Cohen S. X., Diprose J. M., Dym O., Esnouf R. M., Felder C., Ferron F., Guillemot F., Hamer R., Ben Jelloul J. M., Laskowski R. A., Laurent T., Longhi S., Lopez R., Luchinat C., Malet H., Mochel T., Morris R. J., Moulinier L., Oinn T., Pajon A., Peleg Y., Perrakis A., Poch O., Prilusky J., Rachedi A., Ripp R., Rosato A., Silman I., Stuart D. I., Sussman J., Thierry J. -., Thompson J. D., Thornton J. M., Unger T., Vaughan B., Vranken W., Watson J. D., Whamond G. & Henrick K. (2006). Spine Bioinformatics And Data-Management Aspects Of High-Throughput Structural Biology.  ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY. 2006 Oct , 62 :1184-1195.
  11. Albeck S., Burstein Y., Dym O., Jacobovitch Y., Levi N., Meged R., Michael Y., Peleg Y., Prilusky J., Schreiber G., Silman I., Unger T. & Sussman J. (2005). Three-dimensional structure determination of proteins related to human health in their functional context at The Israel Structural Proteomics Center (ISPC).  Acta Crystallographica Section D-Biological Crystallography. 2005 Oct , 61 :1364-1372.
  12. Reichmann D., Rahat O., Albeck S., Meged R., Dym O. & Schreiber G. (2005). The modular architecture of protein-protein binding interfaces.  Proceedings of the National Academy of Sciences of the United States of America. 2005 Jan , 102 (1):57-62.
  13. Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A. (2002). Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.  Journal of Biological Chemistry. 2002 Nov , 277 (48):46304-46309.
  14. Tamary H., Fromovich Y., Shalmon L., Reich Z., Dym O., Lanir N., Brenner B., Paz M., Luder A., Blau O., Korostishevsky M., Zaizov R. & Seligsohn U. (1996). Ala244Val is a common, probably ancient mutation causing factor VII deficiency in Moroccan and Iranian Jews.  Thrombosis and Haemostasis. 1996 Sept , 76 (3):283-291.
  15. Dym O., MEVARECH M. & Sussman J. (1995). Structural Features That Stabilize Halophilic Malate-Dehydrogenase From An Archaebacterium.  Science. 1995 Mar , 267 (5202):1344-1346.