DNA Manipulation Publications

  1. Shraga A., Olshvang E., Davidzohn N., Khoshkenar P., Germain N., Shurrush K., Carvalho S., Avram L., Albeck S., Unger T., Lefker B., Subramanyam C., Hudkins R. L., Mitchell A., Shulman Z., Kinoshita T. & London N. (2019). Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.  Cell Chemical Biology. 2019 Jan , 26 (1):98 - 108.e5.
  2. Meltzer H., Marom E., Alyagor I., Mayseless O., Berkun V., Segal-Gilboa N., Unger T., Luginbuhl D. & Schuldiner O. (2019). Tissue-specific (ts) CRISPR as an efficient strategy for in vivo screening in Drosophila.  Nature Communications. 2019 May , 10 .
  3. Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J. (2019). Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.  PLoS Computational Biology. 2019 Aug , 15 (8).
  4. Cardenas P. D., Sonawane P. D., Heinig U., Jozwiak A., Panda S., Abebie B., Kazachkova Y., Pliner M., Unger T., Wolf D., Ofner I., Vilaprinyo E., Meir S., Davydov O., Gal-On A., Burdman S., Giri A., Zamir D., Scherf T., Szymanski J., Rogachev I. & Aharoni A. (2019). Pathways to defense metabolites and evading fruit bitterness in genus Solanum evolved through 2-oxoglutarate-dependent dioxygenases.  Nature Communications. 2019 Nov , 10 .
  5. Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D. (2019). Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.  ChemPhysChem. 2019 Jul , 20 (14):1860-1868.
  6. Kahlon S., Shreibman D., Unger T., Ben-Yehuda D. & Elias S. (2018). The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition.  Blood Cancer Journal. 2018 May , 8 .
  7. Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M. (2018). Rapid characterization of secreted recombinant proteins by native mass spectrometry.  Communications biology. 2018 Dec , 1 .
  8. Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M. (2018). Rapid characterization of secreted recombinant proteins by native mass spectrometry.  Communications biology. 2018 Dec , 1 .
  9. Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G. (2018). Manipulating the Folding Landscape of a Multi-Domain Protein.  Journal of Physical Chemistry B. 2018 Dec , 122 (49):11030-11038.
  10. Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R. (2018). Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.  Nature Communications. 2018 Sept , 9 .
  11. Bandyopadhyay B. & Peleg Y. (2018). Facilitating circular permutation using Restriction Free (RF) cloning.  PROTEIN ENGINEERING DESIGN & SELECTION. 2018 Mar , 31 (3):65-68.
  12. Baron S., Peleg Y., Grunwald J., Morgenstern D., Elad N., Peretz M., Albeck S., Levin Y., Welch J. T., DeWeerd K. A., Schwarz A., Burstein Y., Diskin R., Shakked Z. & Zimhony O. (2018). Expression of a recombinant, 4 '-Phosphopantetheinylated, active M-tuberculosis fatty acid synthase I in E-coli.  PLoS One. 2018 Sept , 13 (9).
  13. Sonawane P. D., Heinig U., Panda S., Gilboa N. S., Yona M., Kumar S. P., Alkan N., Unger T., Bocobza S., Pliner M., Malitsky S., Tkachev M., Meir S., Rogachev I. & Aharoni A. (2018). Short-chain dehydrogenase/reductase governs steroidal specialized metabolites structural diversity and toxicity in the genus Solanum.  Proceedings of the National Academy of Sciences of the United States of America. 2018 Jun , 115 (23):E5419-E5428.
  14. Sonawane P. D., Pollier J., Panda S., Szymanski J., Massalha H., Yona M., Unger T., Malitsky S., Arendt P., Pauwels L., Almekias-Siegl E., Rogachev I., Meir S., Cardenas P. D., Masri A., Petrikov M., Schaller H., Schaffer A. A., Kamble A., Giri A. P., Goossens A. & Aharoni A. (2017). Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.  Nature Plants. 2017 Jan , 3 (1).
  15. Milrot E., Shimoni E., Dadosh T., Rechav K., Unger T., Van Etten E. J. L. & Minsky A. (2017). Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1.  PLoS Pathogens. 2017 Aug , 13 (8).
  16. Baran D., Pszolla M. G., Lapidoth G. D., Norn C., Dym O., Unger T., Albeck S., Tyka M. D. & Fleishman S. J. (2017). Principles for computational design of binding antibodies.  Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct , 114 (41):10900-10905.
  17. Peleg Y., Prabahar V., Bednarczyk D. & Unger T. (2017). Harnessing the Profinity eXact™ System for Expression and Purification of Heterologous Proteins in E. coli.  . 2017, :33-43.
  18. Bandyopadhyay B., Goldenzweig A., Unger T., Adato O., Fleishman S. J., Unger R. & Horovitz A. (2017). Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL.  Journal of Biological Chemistry. 2017 Dec , 292 (50):20583-20591.
  19. Peleg Y., Prabahar V., Bednarczyk D. & Unger T. (2017). Harnessing the Profinity eXact™ System for Expression and Purification of Heterologous Proteins in E. coli.  . 2017, :33-43.
  20. Pode Z., Peri-Naor R., Georgeson J. M., Ilani T., Kiss V., Unger T., Markus B., Barr H. M., Motiei L. & Margulies D. (2017). Protein recognition by a pattern-generating fluorescent molecular probe.  Nature Nanotechnology. 2017 Dec , 12 (12):1161-1168.