Protein Purification Publications

  1. Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D. (2020). Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.  Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan , 117 (1):395-404.
  2. Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020). Efficient targeted degradation via reversible and irreversible covalent PROTACs.  Journal of the American Chemical Society. 2020 Jul , 142 (27):11734-11742.
  3. Davidi D., Shamshoum M., Guo Z., Bar‐On Y. M., Prywes N., Oz A., Jablonska J., Flamholz A., Wernick D. G., Antonovsky N., Pins B., Shachar L., Hochhauser D., Peleg Y., Albeck S., Sharon I., Mueller‐Cajar O. & Milo R. (2020). Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.  The EMBO Journal. 2020 Sept , 39 (18).
  4. Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J. (2019). Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.  PLoS Computational Biology. 2019 Aug , 15 (8).
  5. Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D. (2019). Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.  ChemPhysChem. 2019 Jul , 20 (14):1860-1868.
  6. Shraga A., Olshvang E., Davidzohn N., Khoshkenar P., Germain N., Shurrush K., Carvalho S., Avram L., Albeck S., Unger T., Lefker B., Subramanyam C., Hudkins R. L., Mitchell A., Shulman Z., Kinoshita T. & London N. (2019). Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.  Cell Chemical Biology. 2019 Jan , 26 (1):98 - 108.
  7. Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D. (2019). Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.  ChemPhysChem. 2019 Jul , 20 (14):1860-1868.
  8. Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R. (2018). Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.  Nature Communications. 2018 Sept , 9 .
  9. Gigli L., Andralojc W., Dalaloyan A., Parigi G., Ravera E., Goldfarb D. & Luchinat C. (2018). Assessing protein conformational landscapes: integration of DEER data in Maximum Occurrence analysis.  Physical Chemistry Chemical Physics. 2018 Nov , 20 (43):27429-27438.
  10. Netzer R., Listov D., Lipsh R., Dym O., Albeck S., Knop O., Kleanthous C. & Fleishman S. J. (2018). Ultrahigh specificity in a network of computationally designed protein-interaction pairs.  Nature Communications. 2018 Dec , 9 (1).
  11. Lapidoth G., Khersonsky O., Lipsh R., Dym O., Albeck S., Rogotner S. & Fleishman S. J. (2018). Highly active enzymes by automated combinatorial backbone assembly and sequence design.  Nature Communications. 2018 Jul , 9 .
  12. Baron S., Peleg Y., Grunwald J., Morgenstern D., Elad N., Peretz M., Albeck S., Levin Y., Welch J. T., DeWeerd K. A., Schwarz A., Burstein Y., Diskin R., Shakked Z. & Zimhony O. (2018). Expression of a recombinant, 4 '-Phosphopantetheinylated, active M-tuberculosis fatty acid synthase I in E-coli.  PLoS ONE. 2018 Sept , 13 (9).
  13. Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G. (2018). Manipulating the Folding Landscape of a Multi-Domain Protein.  Journal of Physical Chemistry B. 2018 Dec , 122 (49):11030-11038.
  14. Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar Avihail A. A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., Amitai G. & Sorek R. (2017). Communication between viruses guides lysis-lysogeny decisions.  Nature. 2017 Jan , 541 (7638).
  15. Baran D., Pszolla M. G., Lapidoth G. D., Norn C., Dym O., Unger T., Albeck S., Tyka M. D. & Fleishman S. J. (2017). Principles for computational design of binding antibodies.  Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct , 114 (41):10900-10905.
  16. Goldenzweig A., Goldsmith M., Hill S. E., Gertman O., Laurino P., Ashani Y., Dym O., Unger T., Albeck S., Prilusky J., Lieberman R. L., Aharoni A., Silman I., Sussman J., Tawfik D. & Fleishman S. J. (2016). Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.  Molecular Cell. 2016 Jul , 63 (2):337-346.
  17. Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D. (2015). [Cover Profile] Sensing Protein Surfaces with Targeted Fluorescent Receptors..  Chemistry (Weinheim an der Bergstrasse, Germany). 2015 Nov , 21 (45):15873-15873.
  18. Dalaloyan A., Qi M., Ruthstein S., Vega S., Godt A., Feintuch A. & Goldfarb D. (2015). Gd(III)-Gd(III) EPR distance measurements - the range of accessible distances and the impact of zero field splitting.  Physical Chemistry Chemical Physics. 2015, 17 (28):18464-18476.
  19. Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A. (2015). A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.  ChemBioChem. 2015 Jul , 16 (10):1415-1419.
  20. Zimhony O., Schwarz A., Raitses Gurevich G. M., Peleg Y., Dym O., Albeck S., Burstein Y. & Shakked Z. (2015). AcpM, the Meromycolate Extension Acyl Carrier Protein of Mycobacterium tuberculosis, Is Activated by the 4 '-Phosphopantetheinyl Transferase PptT, a Potential Target of the Multistep Mycolic Acid Biosynthesis.  Biochemistry. 2015 Apr , 54 (14):2360-2371.