The Helen and Milton A.Kimmelman Center for Biomolecular Structure and Assembly

Ada Yonath, Director
The Martin S. and Helen Kimmel Professorial Chair

The Helen and Milton A. Kimmelman Center for Biomolecular Structure and Assembly, established in 1988, aims at encouraging research at the molecular level on frontier scientific problems concerning the assembly of biological macromolecules into functionally active intracellular units and organelles.

The center is supporting research projects in the following aspects of bio-macromolecular structural research: nucleic-acids and protein expression and purification, crystallization, crystallographic data collection at international state-of-the-art facilities, display and visualization of life processes.

The center is actively involved in educating graduate students and postdoctoral fellows. This includes participation in international conferences and workshop alongside inviting distinguished professors for short and long periods.

It also shares responsibility for various functions of the chemical infrastructure facilities and biological services alongside providing the means for key inter-departmental common facilities.

Funds are being divided into the following categories:

  1. Purchasing, installation, and development of state-of-the-art sophisticated equipment to be used for the investigation of structural aspects of life sciences. Examples are cryo and ambient-temperature X-ray crystallography, NMR spectroscopy, cryo and ambient-temperature EM imaging and time-resolved experiments at the micro-second limits. This includes also the upgrading, maintenance and repair of the existing instrumentation on a regular basis and by emergency calls.

  2. The biocrystallographic laboratory: a common facility for large scale preparations of sensitive biological materials in purity allowing high performance of crystallographic analysis and/or NMR studies.

  3. Funding selected programs of an outstanding quality, albeit premature and/or risky to be funded by the common agencies.

  4. Assisting the first steps of young scientists as well as of more experienced new comers.

  5. Providing means for the organization of conferences, seminars, courses and symposia dealing with aspects of structural biology. Assisting short and long term visits of leading scientific figures as well as post doctoral fellows. Facilitating the attendance of graduate students in workshops and advanced courses, carried out in Israel and/or abroad. The center also stimulates interactions with worldwide experts with specific skills in the area of structural biology.