Open position in 1E Therapeutics

1E Therapeutics (1Etx) is a breakthrough, clinical stage drug development company creating first-in-class RNA-targeting therapeutics based on our proprietary drug design platform. 1E is the culmination of years of innovation, effort, and tens of millions of $US investment in research and development. 

1E's proprietary and groundbreaking rapid drug design process has proven uniquely able to develop innovative drugs that address chronic life threatening indications as well as emerging and evolving pathogens. 1E already has lead compounds that address a wide array of indications in oncology and age-related diseases, immunology, anti-microbial resistance, viral infections, and orphan neurological disorders. 1E’s most advanced lead is already in a Phase 1/2 clinical trial, and the company is positioned to have multiple programs in the clinic within the next 2 years.
We are looking for spirited researchers who will be highly engaged in the company mission to develop novel therapeutics for major unmet medical needs. The scientist will support different aspects of development required for clinical testing, in various therapeutic indications. 

Open position 011 - R&D Scientist 
The scientist will support both proof-of-concept R&D studies and pre-clinical development required for clinical testing, in various therapeutic indications. The position includes a significant component of “wet” bench-work. Candidates are expected to be excellent team players.
We are seeking M.Sc. level candidates with the following requirements:
•    M.Sc. in biology/biochemistry
•    Prior work experience in a drug development company - an advantage
•    Considerable experience with tissue culture and molecular biology work – a must.
•    Excellent inter-personal skills, a team player.
•    Able to perform independent research, including designing and performing experiments, as well as analyzing and presenting data.
•    Self-motivated, passion for science, execution-oriented and deadline driven.
•    Strong organizational and documentation skills.
•    English fluency is an absolute requirement. 

Starting date: June-August 2021
Location: Rehovot

Open position 012 - Bioinformatics Researcher
The scientist will support both proof-of-concept R&D studies and pre-clinical development required for clinical testing, in various therapeutic indications. Candidates are expected to be excellent team players.
We are seeking M.Sc. level candidates for bioinformatics researcher position:
•    M.Sc. in computational biology or computer science 
•    Fluent programing in scripting languages such as: python/R/bash
•    Experience with big data analysis, including next generation sequencing data
•    Enthusiast in research and data mining

Starting date: June-August 2021
Location: Rehovot

Open position 013 - R&D Scientist, Cancer Biology
We are looking for Scientists with a background in cancer biology who will be highly engaged in the company mission to develop novel therapeutics for oncology. 
We are seeking PhD level candidates with the following requirements:
•    Ph.D. in cancer biology.
•    Work experience in a drug development company - an advantage.
•    In-depth knowledge of up-to-date developments in the field, including scientific publications, leading research groups, competitive landscape, etc.
•    Ability to perform independent research, including designing and performing experiments and analyzing and presenting data.
•    Ability to design and analyze animal experiments, and manage their implementation via contract research organizations.
•    The position includes a significant component of “wet” bench-work. 
•    Self-motivated, passion for science, execution-oriented and deadline driven.
•    Strong organizational and documentation skills.
•    English fluency is an absolute requirement.

Starting date: June-August 2021
Location: Rehovot

Open position 014 - Quality Assurance Scientist 
We are looking for Scientists with a background in Quality Assurence who will be highly engaged in the company mission to develop novel therapeutics for major unmet medical needs. The scientist will be working in our Rehovot (pre-Clinical/Clinical QA) or Jerusalem (CMC QA) facility and will support 1ETx Quality development, in various aspects of the company’s activity.
We are seeking PhD/M.Sc. level candidates with the following requirements:
•    PhD/M.Sc. in biology/biochemistry
•    Prior work experience in a QA, in a global environment, either CMC, pre-Clinical or Clinical.
•    Excellent inter-personal and organizational skills.
•    Able to work independently.
•    Self-motivated, passion for science, execution-oriented and deadline driven.
•    Strong organizational and documentation skills.
•    English fluency is an absolute requirement. 

Starting date: June-August 2021
Location: Rehovot

Open position 015 - Oligonucleotide Synthesis/Analysis Scientists
We are looking for Scientists with a background in oligonucleotide synthesis who will be highly engaged in the company mission to develop novel therapeutics for major unmet medical needs. The scientist will be working in our Jerusalem manufacturing facility and will support 1ETx R&D studies and pre-clinical development required for clinical testing, in various therapeutic indications. The position includes working in a manufacturing facility, under GMP/development conditions. Candidates are expected to be excellent team players.
We are seeking M.Sc. level candidates with the following requirements:
•    M.Sc. in biology/biochemistry
•    Prior work experience in a GMP environment - an advantage
•    Considerable experience with oligonucleotide Synthesis/Analysis – a must.
•    Excellent inter-personal and organizational skills.
•    Able to work independently.
•    Self-motivated, passion for science, execution-oriented and deadline driven.
•    Strong organizational and documentation skills.
•    English fluency is an absolute requirement. 

Starting date: June-August 2021
Location: Jerusalem

Open position 016 - Regulatory-Affairs Scientists
We are looking for Scientists with a background in Regulatory Affairs who will be highly engaged in the company mission to develop novel therapeutics for major unmet medical needs. The scientist will be working in our Rehovot facility and will support 1ETx Regulatory strategy development, as well as IND and CTA submissions, in various therapeutic indications and products. 
We are seeking PhD/M.Sc. level candidates with the following requirements:
•    PhD/M.Sc. in biology/biochemistry
•    Prior work experience in a RA, in a global environment 
•    Excellent inter-personal and organizational skills.
•    Able to work independently.
•    Self-motivated, passion for science, execution-oriented and deadline driven.
•    Strong organizational and documentation skills.
•    English fluency is an absolute requirement. 

Starting date: June-August 2021
Location: Rehovot

All candidates are welcome to send their CV with a cover letter to hr@1etx.com