Gene X stress Interaction: Epigenetic Mechanisms

Mapping the stress response: A high-resolution single-cell atlas of the hippocampus.

adiaz — Wed, 21 Jan 2026 14:37:31 +0000

Mapping the stress response: A high-resolution single-cell atlas of the hippocampus. adiaz Wed, 01/21/2026 - 16:37

Our latest publication in Molecular Psychiatry provides the most comprehensive characterization to date of the adult male hippocampus under stress, identifying cell-type specific molecular signatures.

Stress Linked Psychopathologies

Gene X stress Interaction: Epigenetic Mechanisms

Mon, 01/19/2026 - 12:00

https://www.nature.com/articles/s41380-025-03417-y

De Donno C Lopez JP D Luecken M Kos A Brivio E Bordes J Yang H M Deussing J V Schmidt M J Theis F Chen A Single cell characterization of the adult male hippocampus suggests a prominent and cell type specific role for Nrgn and Sgk1 in response to a social

adiaz — Wed, 21 Jan 2026 14:05:48 +0000

De Donno C Lopez JP D Luecken M Kos A Brivio E Bordes J Yang H M Deussing J V Schmidt M J Theis F Chen A Single cell characterization of the adult male hippocampus suggests a prominent and cell type specific role for Nrgn and Sgk1 in response to a social adiaz Wed, 01/21/2026 - 16:05

De Donno C, Lopez JP, D. Luecken M, Kos A, Brivio E, Bordes J, Yang H, M. Deussing J, V. Schmidt M, J. Theis F, Chen A.
Single-cell characterization of the adult male hippocampus suggests a prominent, and cell-type specific, role for Nrgn and Sgk1 in response to a social stressor. Mol Psychiatry. doi: 10.1038/s41380-025-03417-y.

Gene X stress Interaction: Epigenetic Mechanisms

Stress Linked Psychopathologies

Year

2026

Shoshani Haye K Friedlander G Golani O Almeida Correa S Shemesh Y Chen A Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long lasting behavioral abnormalities Neurobiology of Stress doi 10 1016 j

adiaz — Sun, 17 Aug 2025 10:47:42 +0000

Shoshani Haye K Friedlander G Golani O Almeida Correa S Shemesh Y Chen A Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long lasting behavioral abnormalities Neurobiology of Stress doi 10 1016 j adiaz Sun, 08/17/2025 - 13:47

Shoshani-Haye K, Friedlander G, Golani O, Almeida-Correa S, Shemesh Y, Chen A.
Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities. Neurobiology of Stress. doi: 10.1016/j.ynstr.2025.100749.

Stress Circuitry and Regulation

Stress Linked Psychopathologies

Gene X stress Interaction: Epigenetic Mechanisms

Early Life Stress

Year

2025

Group social dynamics in a semi-natural setup reveal an adaptive value for aggression in male mice.

adiaz — Wed, 08 May 2024 10:44:56 +0000

Group social dynamics in a semi-natural setup reveal an adaptive value for aggression in male mice. adiaz Wed, 05/08/2024 - 13:44

Environmental enrichment and oxytocin knockout show opposite effect on aggression and hierarchy structure in male mice.

Stress Circuitry and Regulation

Stress Linked Psychopathologies

Gene X stress Interaction: Epigenetic Mechanisms

Complex Behavior

Sun, 04/28/2024 - 12:00

https://www.biorxiv.org/content/10.1101/2024.04.25.591070v1

Semi-natural setups can contribute to a more complete understanding of dominance and aggression in mice.

adiaz — Wed, 08 May 2024 10:41:27 +0000

Semi-natural setups can contribute to a more complete understanding of dominance and aggression in mice. adiaz Wed, 05/08/2024 - 13:41

Checkout our latest review in Current Opinion in Neurobiology.

Stress Circuitry and Regulation

Stress Linked Psychopathologies

Gene X stress Interaction: Epigenetic Mechanisms

Complex Behavior

Wed, 05/08/2024 - 12:00

https://www.sciencedirect.com/science/article/pii/S0959438824000412

Shemesh Y Benjamin A Shoshani Haye K Yizhar O Chen A Studying dominance and aggression requires ethologically relevant paradigms Current opinion in neurobiology doi 10 1016 j conb 2024 102879

adiaz — Thu, 02 May 2024 11:06:40 +0000

Shemesh Y Benjamin A Shoshani Haye K Yizhar O Chen A Studying dominance and aggression requires ethologically relevant paradigms Current opinion in neurobiology doi 10 1016 j conb 2024 102879 adiaz Thu, 05/02/2024 - 14:06

Shemesh Y, Benjamin A, Shoshani-Haye K, Yizhar O, Chen A.
Studying dominance and aggression requires ethologically relevant paradigms. Current opinion in neurobiology. doi: 10.1016/j.conb.2024.102879.

Gene X stress Interaction: Epigenetic Mechanisms

Complex Behavior

Stress Linked Psychopathologies

Stress Circuitry and Regulation

Year

2024

Lopez JP Chen A Neuropsychiatric research in 2023 mechanisms of stress and therapies The Lancet Neurology doi 10 1016 S1474 4422 23 00469 6

adiaz — Thu, 02 May 2024 10:39:45 +0000

Lopez JP Chen A Neuropsychiatric research in 2023 mechanisms of stress and therapies The Lancet Neurology doi 10 1016 S1474 4422 23 00469 6 adiaz Thu, 05/02/2024 - 13:39

Lopez JP, Chen A.
Neuropsychiatric research in 2023: mechanisms of stress and therapies. The Lancet Neurology. doi: 10.1016/S1474-4422(23)00469-6.

Gene X stress Interaction: Epigenetic Mechanisms

Complex Behavior

Metabolism and stress

Early Life Stress

Stress Linked Psychopathologies

Stress Circuitry and Regulation

Year

2024

דיוקנה של הטראומה במוח צעיר: המנגנון העצבי שמשתבש כתוצאה מחשיפה לאירוע קשה בגיל רך

adiaz — Thu, 28 Dec 2023 09:15:57 +0000

דיוקנה של הטראומה במוח צעיר: המנגנון העצבי שמשתבש כתוצאה מחשיפה לאירוע קשה בגיל רך adiaz Thu, 12/28/2023 - 11:15

מדעני מכון ויצמן למדע חושפים בפירוט חסר תקדים כיצד טראומה בעכברים בני יומם מעצבת את מוחם ופוגעת בתפקודים החברתיים שלהם בבגרות – ומדגישים את חשיבות ההתערבות המוקדמת ליכולת השיקום

Early Life Stress

Gene X stress Interaction: Epigenetic Mechanisms

Stress Linked Psychopathologies

Complex Behavior

Sun, 12/03/2023 - 12:00

Hebrew

https://heb.wis-wander.weizmann.ac.il/life-sciences/n-12078

Kos A Lopez JP Bordes J de Donno C Dine J Brivio E Karamihalev S Luecken MD Almeida Correa S Gasperoni S Dick A Miranda L B ttner M Stoffel R Flachskamm C Theis FJ Schmidt MV Chen A Early life adversity shapes social subordination and cell type specific t

adiaz — Thu, 28 Dec 2023 06:02:44 +0000

Kos A Lopez JP Bordes J de Donno C Dine J Brivio E Karamihalev S Luecken MD Almeida Correa S Gasperoni S Dick A Miranda L B ttner M Stoffel R Flachskamm C Theis FJ Schmidt MV Chen A Early life adversity shapes social subordination and cell type specific t adiaz Thu, 12/28/2023 - 08:02

Kos A, Lopez JP, Bordes J, de Donno C, Dine J, Brivio E, Karamihalev S, Luecken MD, Almeida-Correa S, Gasperoni S, Dick A, Miranda L, Büttner M, Stoffel R, Flachskamm C, Theis FJ, Schmidt MV, Chen A.
Early life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus. Science Advances. doi: 10.1126/sciadv.adj3793.

Early Life Stress

Gene X stress Interaction: Epigenetic Mechanisms

Stress Linked Psychopathologies

Complex Behavior

Year

2023

Lebow M Kuperman Y Chen A Chapter 19 Prenatal induced psychopathologies All roads lead to microglia Stress immunology and inflammation doi 10 1016 B978 0 12 817558 3 00016 0

adiaz — Sun, 22 Oct 2023 07:07:08 +0000

Lebow M Kuperman Y Chen A Chapter 19 Prenatal induced psychopathologies All roads lead to microglia Stress immunology and inflammation doi 10 1016 B978 0 12 817558 3 00016 0 adiaz Sun, 10/22/2023 - 10:07

Lebow M, Kuperman Y, Chen A. Chapter 19 - Prenatal-induced psychopathologies: All roads lead to microglia. Stress: immunology and inflammation. doi: 10.1016/B978-0-12-817558-3.00016-0.

Gene X stress Interaction: Epigenetic Mechanisms

Metabolism and stress

Early Life Stress

Stress Linked Psychopathologies

Year

2023