https://www.weizmann.ac.il/brain-sciences/labs/chen/ en https://www.weizmann.ac.il/brain-sciences/labs/chen/mapping-stress-response-high-resolution-single-cell-atlas-hippocampus <span class="field field--name-title field--type-string field--label-hidden">Mapping the stress response: A high-resolution single-cell atlas of the hippocampus.</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 01/21/2026 - 16:37</span> <div class="clearfix text-formatted"><p>Our latest publication in Molecular Psychiatry provides the most comprehensive characterization to date of the adult male hippocampus under stress, identifying cell-type specific molecular signatures.</p> </div> <div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/5" hreflang="en">Stress Linked Psychopathologies</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/1" hreflang="en">Gene X stress Interaction: Epigenetic Mechanisms</a></div> </div> <div> <img loading="lazy" src="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2026-01/Pablo%202026.png" width="339" height="307" alt="" /> </div> <div><time datetime="2026-01-19T12:00:00Z" class="datetime">Mon, 01/19/2026 - 12:00</time> </div> <div><a href="https://www.nature.com/articles/s41380-025-03417-y">https://www.nature.com/articles/s41380-025-03417-y</a></div> Wed, 21 Jan 2026 14:37:31 +0000 adiaz 241 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/de-donno-c-lopez-jp-d-luecken-m-kos-brivio-e-bordes-j-yang-h-m-deussing-j-v-schmidt-m-j-theis-f <span class="field field--name-title field--type-string field--label-hidden">De Donno C Lopez JP D Luecken M Kos A Brivio E Bordes J Yang H M Deussing J V Schmidt M J Theis F Chen A Single cell characterization of the adult male hippocampus suggests a prominent and cell type specific role for Nrgn and Sgk1 in response to a social </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 01/21/2026 - 16:05</span> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2026-01/Single-cell%20characterization%20-Pablo-2026.pdf" target="blank" ><div class="authors-and-title"><p>De Donno C, Lopez JP, D. Luecken M, Kos A, Brivio E, Bordes J, Yang H, M. Deussing J, V. Schmidt M, J. Theis F, Chen A.<br /> Single-cell characterization of the adult male hippocampus suggests a prominent, and cell-type specific, role for Nrgn and Sgk1 in response to a social stressor. <em>Mol Psychiatry</em>. doi: 10.1038/s41380-025-03417-y.</p> </div></a> <div class="tags-rows-container"> <div class="tags-rows">Gene X stress Interaction: Epigenetic Mechanisms</div> <div class="tags-rows">Stress Linked Psychopathologies</div> </div> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2026-01/Single-cell%20characterization%20-Pablo-2026.pdf" target="blank" ><div class="pdf-download"></div></a> <div> <div>Year</div> <div>2026</div> </div> Wed, 21 Jan 2026 14:05:48 +0000 adiaz 239 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/shoshani-haye-k-friedlander-g-golani-o-almeida-correa-s-shemesh-y-chen-prenatal-stress-induces <span class="field field--name-title field--type-string field--label-hidden">Shoshani Haye K Friedlander G Golani O Almeida Correa S Shemesh Y Chen A Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long lasting behavioral abnormalities Neurobiology of Stress doi 10 1016 j </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Sun, 08/17/2025 - 13:47</span> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2025-08/Keren%202025.pdf" target="blank" ><div class="authors-and-title"><p>Shoshani-Haye K, Friedlander G, Golani O, Almeida-Correa S, Shemesh Y, <strong>Chen A</strong>.<br /> Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities. <em>Neurobiology of Stress. doi: 10.1016/j.ynstr.2025.100749.</em></p> </div></a> <div class="tags-rows-container"> <div class="tags-rows">Stress Circuitry and Regulation</div> <div class="tags-rows">Stress Linked Psychopathologies</div> <div class="tags-rows">Gene X stress Interaction: Epigenetic Mechanisms</div> <div class="tags-rows">Early Life Stress</div> </div> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2025-08/Keren%202025.pdf" target="blank" ><div class="pdf-download"></div></a> <div> <div>Year</div> <div>2025</div> </div> Sun, 17 Aug 2025 10:47:42 +0000 adiaz 237 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/choham-sudre-0 <span class="field field--name-title field--type-string field--label-hidden">Choham Sudre</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Sun, 03/16/2025 - 14:50</span> <div class="clearfix text-formatted"><p>Choham is a neuroscientist investigating how inter-individual variability influences responses to chronic stress and classical antidepressants.</p> </div> <div>Choham Sudre</div> <div class="tags-rows-container"> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/6" hreflang="en">Stress Circuitry and Regulation</a></div> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/5" hreflang="en">Stress Linked Psychopathologies</a></div> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/2" hreflang="en">Complex Behavior</a></div> </div> <div> <img loading="lazy" src="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/styles/members_square/public/2025-03/%D7%A9%D7%95%D7%94%D7%9D_0.jpg?itok=Itfpott5" width="150" height="220" alt="" class="image-style-members-square" /> </div> <div>PhD student</div> <div> <div>Order</div> <div>1</div> </div> Sun, 16 Mar 2025 12:50:32 +0000 adiaz 236 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/choham-sudre <span class="field field--name-title field--type-string field--label-hidden">Choham Sudre</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Sun, 03/16/2025 - 14:48</span> <div class="clearfix text-formatted"><p>Choham is a neuroscientist investigating how inter-individual variability influences responses to chronic stress and classical antidepressants.</p> </div> <div class="tags-rows-container"> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/6" hreflang="en">Stress Circuitry and Regulation</a></div> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/5" hreflang="en">Stress Linked Psychopathologies</a></div> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/2" hreflang="en">Complex Behavior</a></div> </div> <div> <img loading="lazy" src="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/styles/members_square/public/2025-03/%D7%A9%D7%95%D7%94%D7%9D.jpg?itok=w8-8WxZ5" width="150" height="220" alt="" class="image-style-members-square" /> </div> <div>PhD student</div> <div> <div>Order</div> <div>0</div> </div> Sun, 16 Mar 2025 12:48:26 +0000 adiaz 233 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/anpilov-s-shemesh-y-benjamin-biagini-t-umanski-d-zur-y-sztainberg-y-richter-levin-forkosh-o-chen <span class="field field--name-title field--type-string field--label-hidden">Anpilov S Shemesh Y Benjamin A Biagini T Umanski D Zur Y Sztainberg Y Richter Levin A Forkosh O Chen A Group Social Dynamics in a Seminatural Setup Reflect the Adaptive Value of Aggression in Male Mice Biological Psychiatry Global Open Science doi 10 1016</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/13/2024 - 15:25</span> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2024-11/Group-Social-Dynamics-in-a-Seminatural-Setup-Refle_2025_Biological-Psychiatr.pdf" target="blank" ><div class="authors-and-title"><p>Anpilov S, Shemesh Y, Benjamin A, Biagini T, Umanski D, Zur Y, Sztainberg Y, Richter-Levin A, Forkosh O, <strong>Chen A</strong>.<br /> Group Social Dynamics in a Seminatural Setup Reflect the Adaptive Value of Aggression in Male Mice. <em>Biological Psychiatry Global Open Science. doi:10.1016/j.bpsgos.2024.100399.</em></p> </div></a> <div class="tags-rows-container"> <div class="tags-rows">Stress Circuitry and Regulation</div> <div class="tags-rows">Stress Linked Psychopathologies</div> <div class="tags-rows">Complex Behavior</div> </div> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2024-11/Group-Social-Dynamics-in-a-Seminatural-Setup-Refle_2025_Biological-Psychiatr.pdf" target="blank" ><div class="pdf-download"></div></a> <div> <div>Year</div> <div>2025</div> </div> Wed, 13 Nov 2024 13:25:30 +0000 adiaz 230 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/group-social-dynamics-semi-natural-setup-reveal-adaptive-value-aggression-male-mice <span class="field field--name-title field--type-string field--label-hidden">Group social dynamics in a semi-natural setup reveal an adaptive value for aggression in male mice.</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 05/08/2024 - 13:44</span> <div class="clearfix text-formatted"><p>Environmental enrichment and oxytocin knockout show opposite effect on aggression and hierarchy structure in male mice.</p> </div> <div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/6" hreflang="en">Stress Circuitry and Regulation</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/5" hreflang="en">Stress Linked Psychopathologies</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/1" hreflang="en">Gene X stress Interaction: Epigenetic Mechanisms</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/2" hreflang="en">Complex Behavior</a></div> </div> <div> <img loading="lazy" src="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2024-05/otr_ee_news_website.png" width="295" height="307" alt="" /> </div> <div><time datetime="2024-04-28T12:00:00Z" class="datetime">Sun, 04/28/2024 - 12:00</time> </div> <div><a href="https://www.biorxiv.org/content/10.1101/2024.04.25.591070v1">https://www.biorxiv.org/content/10.1101/2024.04.25.591070v1</a></div> Wed, 08 May 2024 10:44:56 +0000 adiaz 223 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/semi-natural-setups-can-contribute-more-complete-understanding-dominance-and-aggression-mice <span class="field field--name-title field--type-string field--label-hidden">Semi-natural setups can contribute to a more complete understanding of dominance and aggression in mice.</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 05/08/2024 - 13:41</span> <div class="clearfix text-formatted"><p>Checkout our latest review in Current Opinion in Neurobiology.<br />  </p> </div> <div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/6" hreflang="en">Stress Circuitry and Regulation</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/5" hreflang="en">Stress Linked Psychopathologies</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/1" hreflang="en">Gene X stress Interaction: Epigenetic Mechanisms</a></div> <div><a href="/brain-sciences/labs/chen/taxonomy/term/2" hreflang="en">Complex Behavior</a></div> </div> <div> <img loading="lazy" src="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2024-05/review_news_website.png" width="337" height="307" alt="" /> </div> <div><time datetime="2024-05-08T12:00:00Z" class="datetime">Wed, 05/08/2024 - 12:00</time> </div> <div><a href="https://www.sciencedirect.com/science/article/pii/S0959438824000412">https://www.sciencedirect.com/science/article/pii/S0959438824000412</a></div> Wed, 08 May 2024 10:41:27 +0000 adiaz 220 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/dr-daniil-umanski <span class="field field--name-title field--type-string field--label-hidden">Dr. Daniil Umanski </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Tue, 05/07/2024 - 11:26</span> <div class="clearfix text-formatted"><p>Daniil develops elaborate data analysis, visualization, and real-time activation methods for neuroscience experiments, using machine learning models to predict animal behavior from video analysis.</p> </div> <div>Dr. Daniil Umanski</div> <div class="tags-rows-container"> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/5" hreflang="en">Stress Linked Psychopathologies</a></div> <div class="tags-rows"><a href="/brain-sciences/labs/chen/taxonomy/term/2" hreflang="en">Complex Behavior</a></div> </div> <div> <img loading="lazy" src="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/styles/members_square/public/2024-05/%D7%93%D7%A0%D7%99%D7%9C%201.jpeg?itok=L4qEkp7s" width="150" height="220" alt="" class="image-style-members-square" /> </div> <div>Data specialist </div> <div> <div>Order</div> <div>4</div> </div> Tue, 07 May 2024 08:26:18 +0000 adiaz 217 at https://www.weizmann.ac.il/brain-sciences/labs/chen https://www.weizmann.ac.il/brain-sciences/labs/chen/shemesh-y-benjamin-shoshani-haye-k-yizhar-o-chen-studying-dominance-and-aggression-requires <span class="field field--name-title field--type-string field--label-hidden">Shemesh Y Benjamin A Shoshani Haye K Yizhar O Chen A Studying dominance and aggression requires ethologically relevant paradigms Current opinion in neurobiology doi 10 1016 j conb 2024 102879</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>adiaz</span></span> <span class="field field--name-created field--type-created field--label-hidden">Thu, 05/02/2024 - 14:06</span> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2024-05/Studying%20dominance%20and%20aggression-Yair%20S-%204.24.pdf" target="blank" ><div class="authors-and-title"><p>Shemesh Y, Benjamin A, Shoshani-Haye K, Yizhar O, <strong>Chen A</strong>.<br /> Studying dominance and aggression requires ethologically relevant paradigms. <em>Current opinion in neurobiology</em>. doi: 10.1016/j.conb.2024.102879.</p> </div></a> <div class="tags-rows-container"> <div class="tags-rows">Gene X stress Interaction: Epigenetic Mechanisms</div> <div class="tags-rows">Complex Behavior</div> <div class="tags-rows">Stress Linked Psychopathologies</div> <div class="tags-rows">Stress Circuitry and Regulation</div> </div> <a href="/brain-sciences/labs/chen/sites/brain-sciences.labs.chen/files/2024-05/Studying%20dominance%20and%20aggression-Yair%20S-%204.24.pdf" target="blank" ><div class="pdf-download"></div></a> <div> <div>Year</div> <div>2024</div> </div> Thu, 02 May 2024 11:06:40 +0000 adiaz 211 at https://www.weizmann.ac.il/brain-sciences/labs/chen