March 23, 2023
The David Lopatie Conference Centre
For conference registration and abstract submission click here
Organizers:
-
Neta Regev-Rudzki
Weizmann Institute of Science -
Jeff Schorey
University of Notre Dame
During the course of an infection, extracellular vesicles (EVs) can disseminate pathogen molecules, which can serve as a source of antigens for an acquired immune response or as agonists of innate immune receptors to promote host defense and immunity. These molecules that include proteins, nucleic acids, lipids and carbohydrates can be incorporation into vesicles that are created and shed by host cells or directly from the pathogen. Involvement of EVs in the induction of immunity and host defense and immune evasion is widespread among many pathogens including viruses, bacteria, fungi and parasites. Thus, EVs play a major role in pathogenesis of an infection and provide exciting potential for the development of novel diagnostic and therapeutic approaches. In this one day symposium you will hear of cutting edge research that expands our understanding of EVs in host-pathogen interaction. Commonalities and differences between pathogens in the context of EV production and function will be highlighted during the meeting.
Meeting Aims:
- Convey the importance of EVs in the host response to a microbial infection
- Contrast and compare the microbial and host content present in EVs following infections with a diverse set of pathogens
- Highlight the potential use of EVs in therapeutics against infectious diseases; including vaccines, diagnostics and drug delivery
- Network with other scientists who share an interest in EVs and pathogen biology
