Deadline for registration
28.2.2023
Deadline for abstract submission
19.1.2023
Program
Extracellular Vesicles: friends and foes II | EVFF 2020 Program
Print Full program| Time | Session/Lecture info |
|---|---|
| 15:30-16:00 | Registration & Coffee
|
| 15:30-16:00 | |
| 16:00-16:15 | Welcome, Opening remarks by the organizing committee
|
| 16:00-16:15 | |
| 16:15-18:45 | Emerging imaging technologies: cell biology, microscopy techniques, and bioimage analysis
Chairs: Yael Heifetz, Yuval Garini, Ori Avinoam |
| 16:15-16:40 |
Ori Avinoam, Weizmann Institute of Science
Imaging across scales with correlative light and election microscopy
|
| 16:40-17:05 |
Eilon Sherman, The Hebrew University of Jerusalem
Single molecule imaging of dynamic protein complexes
|
| 17:05-17:30 |
Yuval Garini, Technion Israel Institute of Technology
Protein dynamics studies in live cells by advanced biophysical methods
|
| 17:30-17:50 |
Coffee Break
|
| 17:50-18:15 |
Assaf Zaritsky, Ben Gurion University
Visual interpretability of deep learning models in cell imaging
|
| 18:15-18:35 |
Romina Macco, Bruker
Multi-Scale Imaging: from Molecules to Organisms using Super-Resolution and Light Sheet Microscopy
|
| 18:35-18:45 |
Discussion
|
| 19:00-20:30 | Speakers (only) dinner at The Koffler Accelerator
|
| 19:00-20:30 |
| Time | Session/Lecture info |
|---|---|
| 08:30-09:00 | Registration & Coffee
|
| 08:30-09:00 | |
| 09:15-09:25 | Symposium opening - Welcome and opening remarks
|
| 09:15-09:25 | |
| 09:25-10:40 | Session 1: EV host-pathogen interaction
Chairs: Marca Wauben & Elie Beit-Yannai |
| 09:25-09:50 |
Neta Regev-Rudzki, Weizmann Institute of Science
The networking platform of the malaria parasite
|
| 09:50-10:15 |
Hailing Jin, University of California
Cross-kingdom RNA trafficking between plants and fungal pathogens
|
| 10:15-10:40 |
Ofir Bahar, Volcani Centre
Synthesis and application of artificial lipid nanoparticles to protect plants from bacterial infection
|
| 10:40-10:55 | Flash talks
Chairs: Marca Wauben & Elie Beit-Yannai |
| 10:40-10:45 |
Julia Bos, Institut Pasteur Paris
Single cell study of the dynamics and role of bacterial EVs in the antibiotic stress response
|
| 10:45-10:50 |
George Dong, Mcgill University
CRISPR/Cas9-mediated disruption of Leishmania major ESCRT pathway impairs small extracellular vesicle production, infectivity, and disease progression
|
| 10:50-10:55 |
Ruby White, University of Edinburgh
Parasitic worm derived extracellular vesicles modulate the host intestinal epithelium in 2-D organoid models
|
| 10:55-11:45 | Coffee Break
|
| 10:55-11:45 | |
| 11:45-13:00 | Session 2: EVs in health and disease I
Chairs: Paulo Pereira & Jonathan Leor |
| 11:45-12:10 |
Tomer Cooks, Ben-Gurion University
The vesicular side of mutant p53: stories about cancer cells, TAMs, CAFs and gram negative bacteria
|
| 12:10-12:35 |
Ziv Gil, Bar Ilan University
Structure and function of an artificial exosome
|
| 12:35-13:00 |
Hector Peinado, Spanish National Cancer Research Center
Defining the role of extracellular vesicles in lymph node premetastatic niche formation
|
| 13:00-13:30 | Lunch
|
| 13:00-13:30 | |
| 13:30-14:30 | Poster session
|
| 13:30-14:30 | |
| 14:30-15:45 | Session 3: Advanced EV biophysical characterization I
Chairs: Amnon Bar-Shir & Marta Bally |
| 14:30-14:55 |
Gijs Wuite, Vrije Universiteit Amsterdam
Competition between Bending and Internal Pressure Governs the Mechanics of Fluid Extracellular Vesicles
|
| 14:55-15:20 |
Mattia Morandi, Czech Academy of Sciences
Extracellular vesicle fusion visualized by cryoEM
|
| 15:20-15:45 |
Rachela Popovtzer, Bar Ilan University
Golden Exosomes: Imaging, Tracking and Patient Stratification
|
| 15:45-15:55 | Flash talks
Chairs: Amnon Bar-Shir & Marta Bally |
| 15:45-15:50 |
Irit Goldian, Weizmann Institute of Science
EVs biophysical properties and function probed by Atomic force microscopy (AFM)
|
| 15:50-15:55 |
Shelly Loewenstein, Tel Aviv medical center-Ichilov
The Role of Human Adipocytes Derived Extracellular Vesicles in Mediating Pancreatic Cancer Growth and Angiogenesis
|
| 15:55-16:35 | Coffee Break
|
| 15:55-16:35 | |
| 16:35-17:50 | Session 4: EV cargo characterization, function & biogenesis I
Chairs: Andrew Hill & Hailing Jin |
| 16:35-17:00 |
Michiel Pegtel, VU University Medical Center
Luminescence-based quantification of secreted CD63 release allows drug screening and reveals inter-organelle communication pathways in exosome biogenesis
|
| 17:00-17:25 |
Michal Sharon, Weizmann Institute of Science
20S proteasomes exported by the malaria parasite promote its growth
|
| 17:25-17:50 |
Motti Gerlic, Tel-Aviv University
Proteomic analysis of necroptotic extracellular vesicles - Insight into their immune regulatory potential
|
| 17:50-18:05 | Flash talks
Chairs: Andrew Hill & Hailing Jin |
| 17:50-17:55 |
Evelyn Lattmann, University of Zurich
Size-exclusion chromatography and data-independent acquisition mass spectrometry improve proteome profiling of extracellular vesicles from plasma and serum of melanoma patients
|
| 17:55-18:00 |
Paula Abou Karam, Weizmann Institute of Science
Uncovering the mechanism of Plasmodium falciparum extracellular vesicle mRNA nuclear localization in host monocytes
|
| 18:00-18:05 |
Jozef Ukropec, Biomedical Research Center, Slovak Acad. Sci.
Extracellular vesicles are modulated by acute endurance exercise and 3-month lifestyle intervention in plasma of sedentary individuals with obesity
|
| 18:05-19:30 | Social Activity Escape Rooms
|
| 18:05-19:30 | |
| 19:30-21:00 | Dinner
|
| 19:30-21:00 |
| Time | Session/Lecture info |
|---|---|
| 08:45-09:15 | Gathering & Coffee
|
| 08:45-09:15 | |
| 09:15-10:55 | Session 5: EVs in health and disease II
Chairs: Hector Peinado & Tomer Cooks |
| 09:15-09:40 |
Marca Wauben, Universiteit Utrecht
Deciphering the cargo-function relationship of milk extracellular vesicle mediated T cell modulation
|
| 09:40-10:05 |
Jacky Goetz, Institut d’Hematologie et d’Immunologie
In vivo and in flow tracking of metastatic EVs
|
| 10:05-10:30 |
Edit Buzas, Semmelweis University
Extracellular vesicles in disguise
|
| 10:30-10:55 |
Dan Offen, Tel-Aviv University
Role of Exosomes in Central Nervous System Diseases
|
| 10:55-11:30 | Coffee Break
|
| 10:55-11:30 | |
| 11:30-12:45 | Session 6: EV cargo characterization, function & biogenesis III
Chairs: Motti Gerlic & Ofir Bahar |
| 11:30-11:55 |
Andrew Hill, La Trobe University
The role of EVs in neurodegenerative diseases
|
| 11:55-12:20 |
Ronit Sagi-Eisenberg, Tel-Aviv University
Cross talk between tumor-derived extracellular vesicles and mast cells
|
| 12:20-12:45 |
Paulo Pereira, NOVA Medical School
Selective sorting of cargo into extracellular vesicles
|
| 12:45-13:00 | Flash talks
Chairs: Motti Gerlic & Ofir Bahar |
| 12:45-12:50 |
Johanna Rettenmeier, Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ)
Oncogenic Dependency of Pediatric Ependymomas on Extracellular Vesicle Pathways
|
| 12:50-12:55 |
Yael Hershkovitz Pollak, Technion
Volatile Markers as Intercellular Communication Agents of Apoptosis
|
| 12:55-13:00 |
Barbara Ukropcova, Institute of Experimental Endocrinolgy, Biomedical research center SAS
Dynamics of extracellular vesicles in serum and cerebrospinal fluid in response to acute exercise in humans: Does the isolation method matter?
|
| 13:00-14:00 | Lunch break & Social Networking
|
| 13:00-14:00 | |
| 14:00-15:15 | Session 7: Cross talk via EVs
Chairs: Ronit Sagi-Eisenberg & Michiel Pegtel |
| 14:00-14:25 |
Yael Heifetz, The Hebrew University of Jerusalem
The whisper of male-female crosstalk
|
| 14:25-14:50 |
Elie Beit-Yannai, Ben-Gurion University
Assessing the contribution of EVs to internal communication within the ocular drainage system under oxidative stress
|
| 14:50-15:15 |
Jonathan Leor, Tel-Aviv University
Cardiac extracellular vesicles drive the pathology of diseases
|
| 15:15-15:35 | Flash talks
Chairs: Ronit Sagi-Eisenberg & Michiel Pegtel |
| 15:15-15:20 |
Alisa Komsky-Elbaz, The Hebrew University of Jerusalem
Extracellular vesicles role in early implantation: the dynamics of embryo-maternal cross talk
|
| 15:20-15:25 |
Marei Sammar, Braude College of Engineering
Augmented PP13 in placental-derived extracellular vesicles (PEVs) in preeclampsia but not in preterm delivery and the impact of corticosteroids
|
| 15:25-15:30 |
Reut noa Ben menachem, The Hebrew University of Jerusalem
Mitochondrial Derived Vesicles retain membrane potential and contain a functional ATP synthase
|
| 15:30-15:35 |
Sharon Ben-Hur, Weizmann Institute of Science
An intruder-targeting system eliminates paternal mitochondria after fertilization in Drosophila
|
| 15:35-16:15 | Coffee Break
|
| 15:35-16:15 | |
| 16:15-16:45 | Poster session
|
| 16:15-16:45 | |
| 16:45-18:00 | Session 8: Advanced EV biophysical characterization II
Chairs: Jacky Goetz & Gijs Wuite |
| 16:45-17:10 |
Marta Bally, Umeá University and Wallenberg Centre for Molecular Medicine
Biophysical approaches to characterize the physicochemical properties of biological nanoparticles and their interactions with the cell surface.
|
| 17:10-17:35 |
Raya Sorkin, Tel-Aviv University
Tetraspanin-mediated migrasome formation
|
| 17:35-18:00 |
Amnon Bar-Shir, Weizmann Institute of Science
In vivo MRI of genetically engineered extracellular vesicles: A SARS-CoV-2 mimetics case-study
|
| 18:00-18:10 | Flash talks
Chairs: Jacky Goetz & Gijs Wuite |
| 18:00-18:05 |
Brachyahu Meir Kestecher, Semmelweis/HCEMM
Association of extracellular vesicles and lipoproteins and their roles in atherosclerosis
|
| 18:05-18:10 |
Nicholas Rogers, Tel Aviv University
Evaluating the Effects of Colloidal Surface Properties of Microbial Extracellular Vesicles on Interactions with Microplastics
|
| 18:10-18:20 | Concluding remarks by Edit Buzas
|
| 18:10-18:20 | |
| 18:20-18:30 | Award Ceremony for the Best Student Poster
|
| 18:20-18:30 | |
| 18:30-20:00 | Dinner
|
| 18:30-20:00 |
| Time | Session/Lecture info |
|---|---|
| 09:00-09:30 | Gathering & Coffee
|
| 09:00-09:30 | |
| 09:30-10:30 | EVs in health and disease III
Chairs: Mattia Morandi & Andrea Gálisová |
| 09:30-09:45 |
Orit Uziel, Rabin Medical Center
Exosomes in polycythemia vera: "mini platelets" with oncogenic and thrombogenic potential
|
| 09:45-10:00 |
Anat Aharon, Sourasky Medical Center
The healing effects of placental extracellular vesicles (EVs) on induced dermal cells function in chronic Graft vs. Host Disease
|
| 10:00-10:15 |
Erez Eitan, NeuroDex
ExoSORT, an immunoaffinity method for isolating blood neuron-derived extracellular vesicles, diagnostic uses
|
| 10:15-10:30 |
Lyora Aharonov, Nurexone Biologic
Extracellular vesicles-based therapy for spinal cord injury
|
| 10:30-11:00 | Coffee break
|
| 10:30-11:00 | |
| 11:00-18:00 | Speakers tour
|
| 11:00-18:00 |
| Time | Session/Lecture info |
|---|---|
| 09:00-09:30 | Satellite Registration and Gathering
|
| 09:00-09:30 | |
| 09:30-09:40 | Opening remarks by Jeff Schorey
|
| 09:30-09:40 | |
| 09:40-10:30 | Viral and Bacterial
Chairs: Amy Buck & Martin Olivier |
| 09:40-10:05 |
Jeff Schorey, University of Notre Dame
Trafficking, Release and Function of EVs during a Mycobacterial Infection
|
| 10:05-10:30 |
Stefan Schild, University Of Gratz
Pathophysiological role of membrane vesicles derived from Vibrio cholerae
|
| 10:30-10:45 | Flash talks
Chairs: Amy Buck & Martin Olivier |
| 10:30-10:35 |
Shachaf Shapira, Weizmann Institute of Science
Elucidating the roles of extracellular signals in the sexual behavior of Caenorhabditis afra
|
| 10:35-10:40 |
Irma Schabussova, Medical University of Vienna
Bacterial extracellular membrane vesicles: The missing link between microbiota and the host immunity?
|
| 10:40-10:45 |
Natalia Osna, University of Nebraska Medical Center
The engulfment of apoptotic bodies by hepatic stellate cells (HSC) promotes liver fibrosis development: the role of HIV and ethanol
|
| 10:45-11:30 | Coffee Break
|
| 10:45-11:30 | |
| 11:30-12:45 | Parasitic I
Chairs: Ana Torrecilhas & Carmen Fernandez |
| 11:30-11:55 |
Amy Buck, Edinburg University
Specificity and function of extracellular vesicles from a gastrointestinal nematode in the mammalian gut
|
| 11:55-12:20 |
Antonio Marcilla, Universitat De Valencia
Extracellular vesicles from trematodes in host-parasite interaction
|
| 12:20-12:45 |
Hernando Del Portillo, Barcelona Institute for Global Health
Reticulocyte-derived exosomes as intercellular communicators in Plasmodium vivax malaria
|
| 12:45-13:05 | Flash talks
Chairs: Ana Torrecilhas & Carmen Fernandez |
| 12:45-12:50 |
Alon Nudelman, Weizmann Institute of Science
Macrophages infected with Salmonella enterica serovar typhimurium secrete proteolytically active extracellular vesicles
|
| 12:50-12:55 |
Daniel Alfandari, Weizmann Institute of Science
Monitoring uptake dynamics of malaria-derived EVs within different re-cipient host immune cells
|
| 12:55-13:00 |
Alberto Ayllon-Hermida, ISGlobal / IGTP
Functional characterization of a hypothetical spleen-dependent P. vivax gene and the role of EVs in spleen-parasite interactions
|
| 13:00-13:05 |
Brbara Teixeira, Instituto de Medicina Molecular - JLA
Detecting the liver stage of Plasmodium infection in circulating extracellular vesicles
|
| 13:05-14:00 | Lunch
|
| 13:05-14:00 | |
| 14:00-15:50 | Chairs: Parasitic II
Chairs: Stefan Schild & Najma Rachidi |
| 14:00-14:25 |
Martin Olivier, McGill University
Leishmania Exosomes and Immune Sensors: A Key Interaction for Effective Infection
|
| 14:25-14:50 |
Ana Torrecilhas, Federal University of Sao Paulo
Extracellular vesicles in Trypanosoma cruzi infection: Host cell communication
|
| 14:50-15:15 |
Carmen Fernandez, Barcelona Institute for Global Health
Plasma-derived EVs as potential biomarkers for chronic Chagas disease
|
| 15:15-15:40 |
Shulamit Michaeli, Bar Ilan University
Exosome and nano tube secretion their content and function in trypanosomatids
|
| 15:40-15:50 | Flash talks
Chairs: Stefan Schild & Najma Rachidi |
| 15:40-15:45 |
Noa Mandelbaum, Technion
Extracellular vesicles of the Gram-positive gut symbiont Bifidobacterium longum induce immune-modulatory, anti-inflammatory effects
|
| 15:45-15:50 |
Simon Remans, KU Leuven
Optimization of a standard protocol for EV isolation from insect hemolymph
|
| 15:50-16:40 | Coffee break & poster session
|
| 15:50-16:40 | |
| 16:40-17:10 | Round tables, Panel discussion: Commonalities and differences in the host EV response to different pathogens
Mediated by: Antonio Marcilla, Amy Buck, Stefan Schild, Neta Regev-Rudzki and Jeff Schorey |
| 16:40-17:10 | |
| 17:10-17:20 | Closing remarks by Hernando Del Portillo
|
| 17:10-17:20 | |
| 17:20-18:05 | Social Activity - Mentalist
|
| 17:20-18:05 | |
| 18:05-19:45 | Dinner
|
| 18:05-19:45 |
Registration_button
Deadline for registration
28.2.2023
Deadline for abstract submission
19.1.2023
Organizing committee
- Neta Regev-Rudzki
Weizmann Institute of Science, Israel - Yael Heifetz
The Hebrew University of Jerusalem - Tomer Cooks
Ben Gurion University of the Negev
Coordinator & Accessibility Issues
Talia Suissa
talia.suissa@weizmann.ac.il
Sponsors
The Chorafas Institute for Scientific Exchange Weizmann Institute of Science
