Program
HPC 2018 Program
Print Full program| Time | Session/Lecture info |
|---|---|
| 16:00-20:30 | Inspirational Talk & Cocktail Dinner
Chair: Andrew Bowie |
| 16:00-16:30 |
Registration and Coffee
|
| 16:30-16:40 |
David Wallach, Weizmann Institute of Sciecne
Opening Remarks
|
| 16:40-17:40 |
Ilan Manulis , Weizmann Institute of Science
Humanity in Space, or: Why We Will Not Reach Mars Anytime Soon
|
| 17:40-18:00 |
Coffee Break
|
| 18:00-18:45 |
Bruce Beutler, University of Texas Southwestern Medical Center
Nobel Prize in Physiology or Medicine, 2011 Keynote speaker: Discovering and solving phenotypes in the mouse with random germline mutagenesis
|
| 18:45-20:30 |
Cocktail Dinner
|
| Time | Session/Lecture info |
|---|---|
| 08:30-09:00 | Registration and Gathering
|
| 08:30-09:00 | |
| 09:00-10:45 | Opening Session
Chair: David Wallach |
| 09:00-09:05 |
Neta Regev Rudzki, Weizmann Institute of Science
Opening Remarks
|
| 09:05-09:10 |
Tue David Bak, Director of the Innovation Centre Denmark in Israel
Opening Remarks by the Danish embassy representative
|
| 09:10-09:15 |
H.E. Alison Kelly, Ambassador of Ireland
Opening Remarks by the Ambassador of Ireland
|
| 09:15-10:00 |
Hanna Engelberg Kulka, The Hebrew University of Jerusalem
Keynote speaker: Stress-induced Hidden Secret of the Genetic Code in Bacteria
|
| 10:00-10:05 |
Anne McGettrick, Trinity College Dublin
Flash Talk: Flash Itaconate is anti-inflammatory in human macrophages but not rheumatoid arthritis synovial fibroblast cells
|
| 10:05-10:10 |
Anne Louise Hansen, Aarhus University
Flash Talk: Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling
|
| 10:10-10:15 |
Keren Yanuka-Golub , Weizmann Institute of Science
Flash Talk: Extra-cellular amyloid fibers act as a cue to promote bacterial migration
|
| 10:15-10:45 |
Coffee Break
|
| 10:45-13:30 | Session 1: Let's start with the host side
Chairs: Christian Holm & Gilad Bachrach |
| 10:45-11:05 |
Søren Paludan, Aarhus University, Denmark
DNA-driven innate immune responses to viral and bacterial infections
|
| 11:05-11:25 |
Michael Berger, The Hebrew University of Jerusalem, Israel
Mitochondrial matrix ATP availability governs hypoxia tolerance in CD8+ T cells
|
| 11:25-11:45 |
William Agace, Technical University of Denmark, Denmark
Diversity and function of intestinal dendritic cells
|
| 11:45-12:05 |
Cord Herbert Brakebusch, Biotech Research & Innovation Center, Denmark
Epigenetic regulation of skin inflammation
|
| 12:05-12:10 |
Joana Santos , Queens University Belfast
Flash Talk: Klebsiella pneumoniae reduces SUMOylation to limit host defence responses
|
| 12:10-12:15 |
Line Reinert, Universtiy of Aarhus
Flash Talk: cGAS-STING activation in microglial cells induces IFN production but also cell death after HSV infection in the CNS
|
| 12:15-13:30 |
Lunch
|
| 13:30-15:05 | Session 2:The Pathogen World
Chairs: Jose Bengoechea & Gabriel Nussbaum |
| 13:30-13:50 |
Neta Regev-Rudzki, Weizmann Institute of Science, Israel
Malaria parasites regulate secretion of EVs carrying distinct cargo
|
| 13:50-14:10 |
Emanuael Hanski , Hebrew University, Israel
Host-Directed Therapy for Streptococcal Infection Based on LL-37 Immunomodulation
|
| 14:10-14:30 |
Peter Nejsum, Aarhus University Hospital, Denmark
Immunomodulation by helminths – a role of extracellular vesicles?
|
| 14:30-14:35 |
Israel Nissan , National Public Health Laboratory
Flash Talk: Delftia spp. kill bacterial pathogens by a combined mechanism of contact dependent and the secretion of antimicrobial compounds
|
| 14:35-14:40 |
Loulieta Nazerai , University of Copenhagen
Flash Talk: A new in vivo model to study protective immunity to Zika virus infection in mice with intact type I interferon signaling
|
| 14:40-14:45 |
Shauna Quinn, Trinity College Dublin
Flash Talk: Helminth products induce anti-inflammatory innate immune training that attenuates the induction of T cell-mediated autoimmune disease
|
| 14:45-15:05 |
Coffee Break
|
| 15:05-17:10 | Session 3: The host wall: Innate immunity
Chairs: Allan Thomsen & SØren Paludan |
| 15:05-15:25 |
Leonie Unterholzner, Lancaster University, UK
Detecting intracellular DNA as "stranger" and "danger" signal
|
| 15:25-15:45 |
Christian Holm, Aarhus University, Denmark
Nrf2/KEAP1 pathway regulates STING in metabolic reprogramming
|
| 15:45-16:05 |
Andrew Bowie, Trinity College Dublin, Ireland
Regulation of cell fate after inflammasome activation
|
| 16:05-17:10 |
Poster Session and Coffee Break
|
| 17:10-20:30 | Session 4: Bacterial pathogens
Chairs: Zvi Hayouka & Eric Campbell |
| 17:10-17:30 |
Gunnar Schoroeder, Queen's University Belfast, Ireland
The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase
|
| 17:30-17:50 |
Neta Sal-Man, Ben Gurion University of the Negev, Israel
The communication among bacterial pathogens
|
| 17:50-18:10 |
Rachel McLoughlin, Trinity College Dublin, Ireland
Characterisation of virulence factors important in S.aureus skin infection to identify new vaccine targets
|
| 18:10-18:30 |
Anat Herskovits, Tel-Aviv University, Israel
Pathogen-phage cooperation during mammalian infection
|
| 18:30-20:30 |
Dinner
|
| Time | Session/Lecture info |
|---|---|
| 08:30-10:30 | Opening Session
Chairs: Roi Avraham & Ultan Power |
| 08:30-09:00 |
Gathering
|
| 09:00-09:45 |
Ralph Isberg, Tufts University, Boston, USA
Keynote speaker Control of host cell tubular endoplasmic reticulum function by Legionella pneumophila
|
| 09:45-09:50 |
Marcin Baran, Trinity College Dublin
Flash Talk: TRANSCRIPTIONAL REGULATION OF CYTOKINE INDUCTION BY MOUSE PYHIN PROTEIN IFI207
|
| 09:50-09:55 |
Li Hui , Biotech Research & Innovation Centre
Flash Talk: Function of N-WASP in host defense
|
| 09:55-10:00 |
Helit Cohen, Sheba Medical Center
Flash Talk: THE c-di-GMP-SPECIFIC PHOSPHODIESTERASE yhjH IS REQUIRED FOR SALMONELLA ENTERICA PARATYPHI A INVASION INTO NONPHAGOCYTIC HOST CELLS
|
| 10:00-10:30 |
Coffee Break
|
| 10:30-13:30 | Session 5: Pathogen-host interactions: Bacteria
Chairs: Anat Herskovits & Leonie Unterholzner |
| 10:30-10:50 |
Rune Hartmann, Aarhus University, Denmark
Molecular mechanism of IRF3 activation – Why phosphorylation of S386 is critical
|
| 10:50-11:10 |
Miguel Valvano, Queen's University Belfast, Ireland
To peroxidate or not? That is the question
|
| 11:10-11:30 |
Roi Avraham, Weizmann Institute of Science, Israel
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells
|
| 11:30-11:50 |
Jose Bengoechea, Queen's University Belfast, Ireland
Two to tango: inflammation, and Klebsiella pneumoniae
|
| 11:50-11:55 |
Noa Tejman Yarden , Ministry of Health Southern District
Flash Talk: Delftibactin-A, a novel Non Ribosomal Peptide with a Broad Antimicrobial Activity.
|
| 11:55-12:00 |
Andrew Cooper , Trinity Biomedical Sciences Institute
Flash Talk: Activation of human Vd2+ T cells by the non-HMBPP expressing Gram positive bacterium Staphylococcus aureus
|
| 12:00-12:05 |
Hadar Ben Zaken, The Hebrew University of Jerusalem
Flash Talk: Breakdown in fighting caries ? novel lytic Phage against Streptococcus Mutans
|
| 12:05-13:30 |
Poster Session & Lunch
|
| 13:30-15:20 | Session 6: Host protection against pathogens
Chairs: William Agace & Nissan Yissachar |
| 13:30-13:50 |
Jakub Abramson, Weizmann Institute of Science, Israel
Breath of Fresh AIRE: From monogenic autoimmunity to anti-fungal response
|
| 13:50-14:10 |
Allan R Thomsen, University of Copenhagen, Denmark
Resident memory T cells in the virus infected CNS.
|
| 14:10-14:30 |
Motti Gerlic, Tel-Aviv University, Israel
Inflammasome activation by Vibrio proteolyticus type VI secretion system
|
| 14:30-14:50 |
David Wallach, Weizmann Institute of Science, Israel
About the raison d’etre of signaling for Programmed Necrosis
|
| 14:50-15:20 |
Coffee Break
|
| 15:20-17:00 | Session 7: Biology of Microorganisms 1
Chairs: Neta Sal-Man & Miguel Valvano |
| 15:20-15:40 |
Eric Campbell, Queen's University Belfast, Ireland
Host metabolic control of microbiota
|
| 15:40-16:00 |
Ohad Gal-Mor, Sheba Medical Center, Israel
The role of the stringent response regulator DksA in Salmonella enterica pathogenicity
|
| 16:00-16:20 |
Oren Kobiler, Tel-Aviv University, Israel
Single cell infection of herpes simplex virus (HSV-1)
|
| 16:20-16:40 |
Ruth Hershberg, Technion, Israel
From boom to bust ? bacterial adaptation to prolonged survival following resource exhaustion
|
| 16:40-17:00 |
Coffee Break
|
| 17:00-20:00 | Session 8: Biology of Microorganisms 2
Chair: Ohad Gal-Mor&Peter Nejsum |
| 17:00-17:20 |
Martin R Jacobsen, Aarhus University, Denmark
Tumorigenesis and regulation of STING signaling
|
| 17:20-17:40 |
Nissan Yissachar, Bar-Ilan University, Israel
Thinking outside the mouse: ex-vivo dissections of enteric neuro-immune-microbiome cross talks
|
| 17:40-18:00 |
Ilana Kolodkin-Gal, Weizmann Institute of Science, Israel
Discovering a novel mineral component of the biofilm extracellular matrix
|
| 18:00-20:00 |
Dinner
|
| Time | Session/Lecture info |
|---|---|
| 08:30-09:45 | Opening Session
Chairs: Rachel McLoughlin & Sharon Karniely |
| 08:30-09:00 |
Gathering
|
| 09:00-09:45 |
Kingston Mills, Trinity College Dublin, Ireland
Keynote speaker: Tissue-resident memory T cells – key mediators of persistent protective immunity against mucosal pathogens
|
| 09:45-11:00 | Session 9: Viruses, Phages and their host
Chairs: Rachel McLoughlin & Sharon Karniely |
| 09:45-10:05 |
Ronen Hazan, The Hebrew University of Jerusalem
From sewage to the patient: phage therapy as a promising solution for the antibiotic resistance crisis
|
| 10:05-10:25 |
Ultan Power, Queen's University Belfast, Ireland
RSV and airway epithelium - identification of molecular factors potentially implicated in severe disease
|
| 10:25-11:00 |
Coffee Break
|
| 11:00-12:20 | Session 10: Viruses, Phages and their host II
Chair: Rune Hartmann & Israel Nissan |
| 11:00-11:20 |
Yaron Vagima, The Israel Institute for Biological Research, Israel
Influenza infection as driver of impaired immunity and lung tissue damage impacts the efficacy of anti-plague antibiotic treatment
|
| 11:20-11:40 |
Gareth Brady , Trinity College Dublin
A Pox on Thee’ Learning how to inhibit human inflammation from Molluscum Contagiosum Virus
|
| 11:40-12:00 |
Martin Kristian Thomsen , Aarhus University
IN VIVO ANTI-VIRAL AND -TUMOR EFFECT OF 3’3’-CAIMP STING ACTIVATION
|
| 12:00-12:20 |
Ziv Shulman , Weizmann Institute of Science, Israel
Dynamics of antibody-mediated immune response in intestinal tissues
|
| 12:20-14:00 | Closing session
Chairs: Andrew Bowie and Ronen Hazan |
| 12:20-12:30 |
Travel Award Ceremony
|
| 12:30-12:40 |
Andrew Bowie and Ronen Hazan
Concluding Remarks
|
| 12:40-14:00 |
Lunch
|
| 14:00-22:00 | Tour to Tel Aviv
|
| 14:00-22:00 |