Recent Publications
- Mol
Cell. 2006 Jun 23;22(6):741-53
Structural Basis of DNA Recognition by
p53 Tetramers.
Kitayner M, Rozenberg H, Kessler N, Rabinovich D, Shaulov L,
Haran TE and Shakked Z.
- Nucleic
Acids Res. 2005 Dec 13;33(22):7048-57
Molecular flexibility in ab
initio drug docking to DNA binding and binding-mode transitions in all-atom
Monte Carlo simulations.
Rohs R, Bloch I, Sklenar H and Shakked Z.
- Structure.
2005 Oct;13(10):1499-509
Structural and energetic origins of
sequence-specific DNA bending: Monte Carlo simulations of papillomavirus
E2-DNA binding sites.
Rohs R, Sklenar H and Shakked Z.
- Acta
Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt3): 236-46.
Structures of
the DNA-binding site of Runt-domain transcription regulators.
Kitayner M,
Rozenberg H, Rabinovich D, Shakked Z.
- Proc
Natl Acad Sci USA. 2004 Jun 1;101(22):8337-41
Predicting indirect
readout effects in protein-DNA interactions.
Zhang Y, Xi Z, Hegde RS,
Shakked Z and Crothers DM.
- Structure
(Camb). 2002 Oct;10(10):1395-407
DNA recognition by the RUNX1
transcription factor is mediated by an allosteric transition in the RUNT
domain and by DNA bending.
Bartfeld D, Shimon L, Couture GC, Rabinovich D,
Frolow F, Levanon D, Groner Y, Shakked Z
- Oncogene.
2002 Aug 1;21(33):5117-26
DNA binding and 3'-5' exonuclease activity in
the murine alternatively-spliced p53 protein.
Shakked Z, Yavnilovitch M,
Kalb Gilboa AJ, Kessler N, Wolkowicz R, Rotter V, Haran TE.
- J
Mol Biol. 2001 Oct 12;313(1):229-37.
A standard reference frame for the
description of nucleic acid base-pair geometry.
Olson WK, Bansal M, Burley
SK, Dickerson RE, Gerstein M, Harvey SC, Heinemann U, Lu XJ, Neidle S, Shakked
Z, Sklenar H, Suzuki M, Tung CS, Westhof E, Wolberger C, Berman HM.
- Proc
Natl Acad Sci U S A. 2001 Jul 17;98(15):8490-5.
DNA bending by an
adenine--thymine tract and its role in gene regulation.
Hizver J, Rozenberg
H, Frolow F, Rabinovich D, Shakked Z.
- J
Mol Biol. 2000, 300, 819-840
A-form conformational motifs in
ligand-bound DNA structures.
Lu X-J., Shakked, Z., Olson, WK
- Oxford Handbook of Nucleic Acid Structure (Neidle S. ed.). Oxford Univ.
Press Inc., pp 455-468(1999).
DNA bending by adenine-thymine tracts.
Crothers DM, Shakked Z
- J
Biomol Struct Dyn 1999 Feb;16(4):775-85
Left-handed DNA crossovers.
Implications for DNA-DNA recognition and structural alterations.
Timsit Y,
Shatzky-Schwartz M, Shakked Z
- Acta
Crystallogr D Biol Crystallogr 1998 Nov 1;54(2 ( Pt
6)):1336-42
Molecular replacement: the revival of the molecular Fourier
transform method.
Rabinovich D, Rozenberg H, Shakked Z
- Proc
Natl Acad Sci U S A 1998 Dec 22;95(26):15194-9
Structural code for DNA
recognition revealed in crystal structures of papillomavirus E2-DNA
targets.
Rozenberg H, Rabinovich D, Frolow F, Hegde RS, Shakked Z
- J
Mol Biol. 1998 Jun 26;279(5):1123-36.
On the potential role of the
amino nitrogen atom as a hydrogen bond acceptor in macromolecules.
Luisi B,
Orozco M, Sponer J, Luque FJ, Shakked Z
- J
Mol Biol. 1997 Apr 4;267(3):595-623.
X-ray and solution studies of DNA
oligomers and implications for the structural basis of A-tract-dependent
curvature.
Shatzky-Schwartz M, Arbuckle ND, Eisenstein M, Rabinovich D,
Bareket-Samish A, Haran TE, Luisi BF, Shakked Z
- Proc
Natl Acad Sci U S A. 1997 Apr 1;94(7):2993-8.
Local DNA stretching
mimics the distortion caused by the TATA box-binding protein.
Lebrun A,
Shakked Z, Lavery R
- Nat
Struct Biol. 1996 Jan;3(1):32-7.
A novel form of the DNA double helix
imposed on the TATA-box by the TATA-binding protein.
Guzikevich-Guerstein
G, Shakked Z
- J
Mol Biol. 1995 May 5;248(3):662-78.
Hydration patterns and
intermolecular interactions in A-DNA crystal structures. Implications for DNA
recognition.
Eisenstein M, Shakked Z
- Nature.
1994 Mar 31;368(6470):469-73.
Determinants of repressor/operator
recognition from the structure of the trp operator binding site.
Shakked Z,
Guzikevich-Guerstein G, Frolow F, Rabinovich D, Joachimiak A, Sigler
PB
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Weizmann Institute of
Science, Rehovot, 76100 Israel
Tel: (972)-8-934-2672; Fax: (972)-08-9344154, (972)-8-934-4136
Email: zippi.shakked@weizmann.ac.il
