Yair Reisner Professor Yair Reisner, Department Head
The Henry H. Drake Professor of Immunology
E-mail: yair.reisner@weizmann.ac.il
Phone: +972-8-934-4023
Fax: +972-8-947-4141
Location: Wolfson Bldg., Room 014

 Relevant Publications

  1. Reisner, Y. Hematopoietic stem cell transplantation across major genetic barriers. (Plenary lecture: Inaugural meeting of the Robert A. Good Immunology Society, June 9-11, 2006, Tampa, Florida). Immunol. Res. 2007, In Press.

  2. Aversa, F., Terenzi, A., Tabilio, A., Velardi, A., Carotti, A., Falcinelli, F., Ballanti, S., Falzetti, F., Felicini, R., Ruggeri, L., Perruccio, K., Aloisi, T., Saab, J-P., Santucci, A., Martelli, M.P., Mecucci, C., Aristei, C., Latini, P., Reisner, Y. and Martelli, FM. Full Haplotype Mismatched Haematopoietic Stem Cell Transplantation: Outcomes in 104 Patients with Acute Leukemia at High Risk of Relapse. J Clin Oncol., 23(15):3447-54 (2005).

  3. Dekel, B., Burakova, T., Arditti, F., Reich-Zeliger S., Aviel-Ronen, S., Rechavi, G., Kaminski, N.,. Passwell, JH, and Reisner, Y. Human and Porcine Early Kidney Precursors as a New Source for Transplantation. Nature Medicine, 9 (1):53-60 (2003).

  4. Reisner, Y. Growing organ for transplantation from embryonic precursor tissues. (Deans Lecture Series, June 8, 2006 at South Florida Tampa Campus.) Immunol. Res. 2007. In Press.

  5. Eventov-Friedman*, S., Katchman*, H., Shezen, E., Aronovich, A., Tchorsh, D., Dekel,B., Freud E. and Yair Reisner.. "Embryonic Pig Liver, Pancreas and Lung as a Source for Transplantation: Optimal Organogenesis without Teratoma Depends on Distinct Time Windows". PNAS, 102(8):2928-2933 (2005).

  6. Katchman, H., Eventov-Friedman, S., Aronovitch, A., Tchorsh, D., Shezen, E., Shtabsky, A., Dekel, B., Blazar, BR., Freud, E. and Reisner, Y. Embryonic porcine liver as a source for transplantation: Advantage of intact liver implants over isolated hepatoblasts in overcoming homeostatic inhibition by the quiescent host liver. Stem Cells. Under revision.

  7. Aronovich, A., Tchorsh, D., Katchman, HM., Eventov-Friedman, S.M., Shezen, E., Martinowitz, U., Blazar, BR., Cohen, S., Tal, O. and Reisner, Y. Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation. PNAS, 103(50):19075-19080 (2006).

  8. Eventov-Friedman, S., Tchorsh, D., Katchman, H., Shezen, S., Aronovich, A., Hecht, G., Dekel, B., Rechavi, G., Blazar, B.R., Feine, I., Tal, O., Freud, E. and Reisner, Y. Embryonic Pig Pancreatic Tissue Transplantation for the Treatment of Diabetes. PloS Med., 3(7) 2006. e215. [Epub ahead of print].

  9. The role of Veto cells in bone marrow transplantation. Assorted references.

  10. Bachar-Lustig, E., Reich-Zeliger, S. and Reisner, Yair. Anti-Third Party Veto CTLs Overcome Rejection of Hematopoietic Allografts: Synergism with Rapamycin and BM cell dose. Blood, 102 ( 6):1943-1950. (2003). Plenary paper.

  11. Aviner, S., Yao, X., Krauthgamer, R., Gan, J., Goren, R., Klein, T., Tabilio, A.,. McMannis, J.D., Champlin R., Martelli, M.F., Bachar-Lustig, E. and Reisner, Y. Large scale preparation of human anti-3rd party veto CTLs depleted of GVH reactivity: a new source for graft facilitating cells in BMT. Human Immunology, 66, 644�652 (2005).

  12. Gur, H., Krauthgamer, R., Berrebi, A., Klein, T., Nagler, A., Tabilio, A., Martelli, M .F. and Reisner, Y. Tolerance induction by megadose hematopoetic progenitor cells: expansion of veto cells by short term culture of purified human CD34+ cells. Blood, 99(11):4174-4181 (2002).

  13. Gur, H., Krauthgamer, R., Bachar-Lustig, E., Katchman, H., Arbel-Goren, R., Berrebi, A., Klein, T., Nagler, A., Tabilio, A., Martelli, M.F. and Reisner, Y. Immune regulatory activity of CD34+ progenitor cells: evidence for a deletion based mechanism TNF-α. Blood, 105(6):2585-93 (2005).

  14. Reich-Zeliger, S., Bachar-Lustig, E., Gan, J. and Reisner Y. Tolerance induction by veto CTLs in the TCR transgenic 2C mouse model: I. Relative reactivity of different veto cells. J Immunology, 1:173(11):6654-9 (2004).

  15. Reich-Zeliger, S., Gan, J., Bachar-Lustig, E. and Reisner Y. Tolerance induction by veto CTLs in the TCR transgenic 2C mouse model: II. Deletion of effector cells by Fas-FasL apoptosis. J Immunology, 1:173(11):6660-6 (2004).

  16. Reich-Zeliger, S., Bachar-Lustig, E., Bar-Ilan, A., and Reisner, Y. Tolerance induction in pre-sensitized bone marrow recipients by veto CTLs: Effective deletion of host anti-donor memory effector cells. Under revision at Journal of Immunology, In Press.

  17. Arditti, FD., Aviner, S., Dekel, B., Krauthgamer, R., Gan, J., Nagler, A., Tabilio, A., Martelli, M., Berrebi, A. and Reisner, Y. Eradication of B-CLL by Allogeneic Host Non-Reactive Anti-Third Party CTLs. Blood, 105(8):3365-71 (2005).

  18. Steiner, D., Brunicki, B., Bachar-Lustig, E., Taylor, P.A., Blazar , B.R. and Reisner, R. Overcoming T cell mediated rejection of bone marrow allografts by Treg cells: synergism with veto cells and Rapamycin. Experimental Hematol., 34(1):66-71 (2006).

  19. Steiner, D., Brunicki, N., Blazar, BR., Bachar-Lustig, E. and Reisner, R. Tolerance Induction By Third Party �off-the-shelf� CD4+C25+ Treg Cells. Experimental Hematol., 34(1):66-71 (2006).