Human evolution and disease

Studying cell-cell communication mechanisms of malaria parasites within a population and with their hosts

We use computers, chemistry and biology to design covalent ligands for interesting proteins, to understand biology and discovery drugs

We study interactions between peripheral circadian clocks and exercise physiology, hypoxia signaling and metabolic pathways

Functional genomics and systematic screens to uncover new protein functions

We develop algorithms for enzyme and antibody design and verify them using high-throughput experiments.

The interplay between viruses and their hosts