Publications | Department of Molecular Cell Biology

2026

Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinsons disease: a randomized double-blind prospective study

Hegelmaier T., Duscha A., Desel C., Fuchs S., Shapira M., Amidror S., Shan Q., Stangl G. I., Hirche F., Kempa S., Maifeld A., Würtele L. M., Peplinski J., Jauk D., Naim G., Shidlovsky N., Cohen A., Bennet Y., Paschold L., Dumitru C. A., Obermüller-Jevic U., Hustvedt S. O., Timmesfeld N., Gold R., Zapf A., Binder M., Sandalcioglu I. E., Mostaghim S., Przuntek H., Segal E., Yissachar N. & Haghikia A. (2026), Scientific Reports. 16, 1, 315

Psychological stress and eating behaviors as interacting influences on patientreported disease activity in Italian patients with inflammatory bowel disease

Usta D., Acampora M., Pereira A. C., Savarese M., De Rocchis M. S., Avedano L., Leone S., Graffigna G., Salathé M., Burisch J., Halfvarsson J., Gluschak V., Segal E., Weersma R., Huber S., Skiecevičienė J. & Franke A. (2026), Scientific Reports. 16, 1, 322

A founder heterozygous mutation in methyl-CpG binding domain protein 4 (MBD4) prevalent among Israeli Christian Arabs predisposes to increased mutagenesis

Dadi G., Rosen S., Naor H., Hellou E., Chapal-Ilani N., Bacharach T., Kaushansky N. & Shlush L. L. (2026), Haematologica. 111, 3, p. 1034-1038

Pitfalls in analysis and interpretation of single-cell RNA-seq data in cancer

Tirosh I. (2026), Neuro-Oncology Advances. 8, Suppl 1, p. i57-i60

Co-Biotics - Dual modulation of the host and the microbiota

Versalovic J., Segal E., Mayer E. A., Gibson G. R., Morelli L. & Reid G. (2026), Trends in Food Science and Technology. 169, 105561

Personalized Dietary Feedback Mediates the Association of Dietary Self-Monitoring Adherence and Weight Loss: A Post Hoc Analysis of the Personal Diet Study

Berube L. T., Wang C., Curran M., Pompeii M. L., Hu L., Barua S., Li H., St-Jules D. E., Schoenthaler A., Segal E., Bergman M. & Popp C. J. (2026), Journal of Nutrition. 156, 3, 101364

The Evolving Landscape of Single-Cell Genomics in CNS and PNS Oncology

Ellenbogen Y., Suva M. L. & Tirosh I. (2026), Neuro-Oncology Advances. 8, p. i1-i3

A foundation model for continuous glucose monitoring data

Lutsker G., Sapir G., Shilo S., Merino J., Godneva A., Greenfield J. R., Samocha-Bonet D., Dhir R., Gude F., Mannor S., Meirom E., Xing E. P., Chechik G., Rossman H. & Segal E. (2026), Nature. 650, 8103, p. 978-986

Localization of Asgard archaeal ESCRT proteins to eukaryotic cellular structures

Naripogu K. B., Tee Y. H., Senju Y., Bershadsky A. & Robinson R. C. (2026), Biochemical and Biophysical Research Communications. 802, 153301

Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation

Rondeau V., Bansal S., Buttigieg M. M., Zeng A. G., Chan D. Y., Chan-Seng-Yue M., Jin L., McLeod J., Kates M., Donato E., Stelmach P., Vlasschaert C., Yang Y., Gupta A., Genta S., Sanz-Garcia E., Shlush L., Ribeiro M., Butler M. O., Abelson S., Minden M. D., Saibil S. D., Chan S. M., Rauh M. J., Trumpp A., Dick J. E. & Vanner R. J. (2026), Cancer Research. 86, 4, p. 845-857

Temporal tissue dynamics from a spatial snapshot

Somer J., Mannor S. & Alon U. (2026), Nature. 650, 8101, p. 490-499

Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus treatment in a clinical trial

Meylan M., Tian Y., Wu L., Ling A. L., Kovarsky D., Barlow G. L., Nguyen L. D., Pyrdol J., Marx S., Westphal L., Michel J., Gonzalez Castro L. N., Dumont S., Santos A., Tirosh I., Suvà M. L., Chiocca E. A. & Wucherpfennig K. W. (2026), Cell
Submitted Version

Analysis of biomarkers in the Human Phenotype Project using disease models from UK Biobank

Pellow D., Geva G. A., Godneva A., Reisner Y., Talmor-Barkan Y. & Segal E. (2026), Med, 100993

SGAC: a graph neural network framework for imbalanced and structure-aware AMP classification: a graph neural network framework for imbalanced and structure-aware AMP classification

Wang Y., Liang V., Yin N., Liu S. & Segal E. (2026), Briefings in Bioinformatics. 27, 1, bbag038

Harnessing glucocorticoid receptor antagonism to enhance the efficacy of cardiac regenerative growth factors and cytokines

Da Pra S., Boriati S., Miano C., Sacchi F., Batho C., Bongiovanni C., Del Bono I., Aharonov A., Pianca N., Tassinari R., Dahir R., Ventura C., Lauriola M., Tzahor E., Wilson C. H. & DUva G. (2026), Nature Cardiovascular Research. 5, 2, p. 118-137

High-dimensional imaging using combinatorial channel multiplexing and deep learning

Ben-Uri R., Ben Shabat L., Shainshein D., Bar-Tal O., Bussi Y., Maimon N., Keidar Haran T., Milo I., Goliand I., Addadi Y., Salame T. M., Rochwarger A., Schürch C. M., Bagon S., Elhanani O. & Keren L. (2026), Nature biotechnology. 44, 2, p. 233-246

Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer

Gumpert N., Sagie S., Arnedo-Pac C., Babu T., Weller C., Gonzalez-Perez A., Wang Y., Todó L. M., Levy R., Chen X., Greenberg P., Dayan-Rubinov M., Yakubovich E., Wasserman-Bartov T., Zerbib M., Gong J., Rebernick R. J., Tercero A. O., Muriel L. A., Benedek G., Kedmi M., Oren R., Ben-Dor S., Levin Y., Troyanskaya O. G., Munzur A. D., Wyatt A. W., Cieslik M. P., Quigley D. A., Van Allen E. M., Anandasabapathy N., Mateo J., Yang X., Martínez-Jiménez F., Lopez-Bigas N. & Samuels Y. (2026), Cancer Discovery. 16, 2, p. 250-269

Heritability of intrinsic human life span is about 50% when confounding factors are addressed

Shenhar B., Pridham G., De Oliveira T. L., Raz N., Yang Y., Deelen J., Hägg S. & Alon U. (2026), Science. 391, 6784, p. 504-510

From Plato to Pareto: Defining the shape of infections disease space

Lebel Y., Gupta A. S., Chevée V., Alon U. & Schneider D. S. (2026), Science advances. 12, 5, eaeb3911

NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction

Jankelow A., Godneva A., Rein M., Samocha-Bonet D., Weissglas-Volkov D., Zohar S., Shor T. & Segal E. (2026), npj Digital Public Health. 1, 1, 1

The Highly Localized Interaction between Neurofascin-186 and Gliomedin Promotes Subcellular Innervation by the Chandelier Cell

Hayano Y., Ishino Y., Bhat M. A., Peles E. & Taniguchi H. (2026), The Journal of neuroscience : the official journal of the Society for Neuroscience. 46, 2

N1-Methylpseudouridine directly modulates translation dynamics

Rozman B., Broennimann K., Rajan K. S., Nachshon A., Saha C., Arazi T., Mohan V., Geiger T., Wollner C. J., Richner J. M., Westhof E., Yonath A., Bashan A. & Stern-Ginossar N. (2026), Nature

Design of bacterial DNT sensors based on computational models

Bahiri Elitzur S., Shpigel E., Katzir I., Alon U., Belkin S. & Tuller T. (2026), Nucleic Acids Research. 54, 1, gkaf1482

HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

Chemla Y., Itzhaki O., Melamed S., Weller C., Sade Y., Manich P., Reshef K., Xenidis N., Maliah A., Levy G., Parikh R., Bartok O., Levy O., Tal I., Aziel G., Nissani A., Yunger S., Likonen D., Kliminsky V., Golan T., Capron C., Ace V., Levy R., Rasoulouniriana D., Eyal Z., Barzilay Y., Balaban R., Khateeb A., Khosravi R., Grau A., Ziv T., Greenberg P., Netanely D., Vaknin H., Wu X., Amitay Y., Brenner R., Martínez Gómez J. M., Hershkovitz D., Yardeni T., Zemser-Werner V., Kobiler O., Friedmann Y., Bassan D., Shamir R., Eisenbach L., Santana-Magal N., Milyavsky M., Eisenberg G., Keren L., Cohen M., Gur D., Barak B., Lotem M., Sprinzak D., Greenberger S., Fisher D., Besser M. J., Khaled M., Close P., Shapira R., Apcher S., Madi A., Levesque M. P., Rapino F., Carmi Y., Parikh S., Samuels Y. & Levy C. (2026), Cell. 189, 1, p. 233-251.e29

HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

The legacy of a gentleman scientist: Pierre Hainaut

Arnoult C., Attardi L. D., Batsheva K., Blandino G., Burns K. H., Del Sal G., Kirsch D. G., Lane D. P., Levine A. J., Lozano G., Malkin D., Melino G., Oren M., Prives C. & Schramek D. (2026), Cell Death and Differentiation. 33, 1, p. 1-2

Towards a reference cell atlas of liver diversity over the human lifespan

Taylor S. A., Bader G. D., MacParland S., Mullen A. C., Andrews T., Cuenca A. G., DasGupta R., Gehring A. J., Grün D., Guilliams M., Gulamhusein A., Henderson N. C., Hirschfield G., Huppert S. S., Itzkovitz S., Jiang Z. G., Lauer G. M., McGilvray I., Mysore K. R., Pirola C. J., Quon G., Rahbari M., Regev A., Ricciuto A., Scott C. L., Sharma A., Sookoian S., Tana M. M., Teichmann S. A., Vallier L., Vlachos I. S., Wang B. & Zhen M. (2026), Nature Reviews Gastroenterology and Hepatology. 23, 1, p. 97-109

p53 inactivation drives breast cancer metastasis to the brain through SCD1 upregulation and increased fatty acid metabolism

Laue K., Pozzi S., Zerbib J., Bertolio R., Eliezer Y., Cohen-Sharir Y., Winkler T., Caputo M., Ricci A. A., Adler L., Khoury R., Longobardi G., Slutsky R., Leikin-Frenkel A. I., Ovadia S., Lange K., Rustighi A., Piazza S., Sacconi A., Magesh R. Y., Keller F. N., Berthelet J., Schäffer A., Saad R., Israeli Dangoor S., Szczepanowska K., Barshack I., Liao Y., Malitsky S., Brandis A., Broggini T., Czabanka M., Shi W., Merino D., Watson E. V., Blandino G., Erez A., Ashery-Padan R., Medyouf H., Bertero L., Del Sal G., Satchi-Fainaro R. & Ben-David U. (2026), Nature Genetics. 58, 1, p. 116-131

Inhibition of Tumor Microenvironment-Driven JAK-STAT Signaling Enhances Response to Arginine Deprivation Therapy in Triple-Negative Breast Cancer

Tishler H., Ziman S., Cheng K., Wang K., Sanghvi N., Adler L., Stelzer G., Maniriho H., Dassa B., Bab-Dinitz E., Levi M., Galai S., Goldman O., Ariav Y., Darzi N., Ezagouri S., Nimni N., Rosenfeld N., Rotkopf R., Brandis A., Mehlman T., Oren R., Zerbib M., Kuznetsov Y., Donzelli S., Blandino G., Seger R., Ruppin E. & Erez A. (2026), Cells. 15, 1, 25

2025

Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation

Sagie S., Babu T., Weller C., Tabachnik C., Livneh I., Quast N. P., Gumpert N., Shomuradova A., Raybould M. I., Levy R., Malko D., Alfia A., Ben Lulu T., Alon M., Herrera F., Kutuzov M., Zerbib M., Greenberg P., Wasserman-Bartov T., Benedek G., Levin Y., Stossel C., Kamer I., Golan T., Oren R., Shmueli M., Bartok O., Bar J., Cohen J., Dushek O., Deane C. M. & Samuels Y. (2025), Cell Reports Medicine. 6, 12, 102506

Transcriptomic profiling of shed cells enables spatial mapping of cellular turnover in human organs

Barkai T., Yakubovsky O., Korem Kohanim Y., Bahar Halpern K., Shir S., Oren N., Fine M., Kelmer P., Talmon A., Israeli A., Pencovich N., Pery R., Nachmany I. & Itzkovitz S. (2025), Molecular Systems Biology. 21, 12, p. 1778-1792

Molecular Systems Biology at 20: reflecting on the past, envisioning the future

Bheda P., Hou J., Aebersold R., Alon U., Bader J. S., Bardwell L., Liu E. T., Locke J. C., Mann M., Millar A. J., Naef F., Pilpel Y., Shamir R. & Vitkup D. (2025), Molecular Systems Biology. 21, 12, p. 1667-1673

Crohns disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset

Bourgonje A. R., Andreu-Sánchez S., Gacesa R., Innocenti G., Kalka I. N., Klompus S., Leviatan S., Schlesinger Y., Krongauz D., Weinberger A., Van der Vegt B., Fu J., Segal E., Zhernakova A., Vogl T. & Weersma R. K. (2025), Gut. 74, 12, p. 1977-1988

A Drosophila screen of schizophrenia genes highlights neural and glial MMPs in neuronal remodeling

Keret S., Meltzer H., Marmor-Kollet N. & Schuldiner O. (2025), Life Science Alliance. 8, 12, e202503504

A single-cell atlas of Schwannoma across genetic backgrounds and anatomic locations

Gonzalez Castro L. N., Gavish A., Bussema L., Mount C. W., Neftel C., Nomura M., Chiocca E. A., Bi W. L., Arnaout O., Barker F. G., Brown J. M., Jordan J. T., Batchelor T. T., Stemmer-Rachamimov A., Plotkin S. R., Tirosh I. & Suvà M. L. (2025), Genome Medicine. 17, 1, 37

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Dadiani M., Friedlander G., Perry G., Balint-Lahat N., Gilad S., Morzaev-Sulzbach D., Shenoy A., Bossel Ben-Moshe N., Pavlovsky A., Bernstein-Molho R., Domany E., Barshack I., Geiger T., Kaufman B. & Gal-Yam E. N. (2025), Molecular Oncology. 19, 12, p. 3665-3684

Generative AI enables medical image segmentation in ultra low-data regimes

Zhang L., Jindal B., Alaa A., Weinreb R., Wilson D., Segal E., Zou J. & Xie P. (2025), Nature Communications. 16, 1, 6486

Compression of morbidity by interventions that steepen the survival curve

Yang Y., Mayo A., Levy T., Raz N., Shenhar B., Jarosz D. F. & Alon U. (2025), Nature Communications. 16, 1, 3340

Fibro predict a machine learning risk score for advanced liver fibrosis in the general population using Israeli electronic health records

Kalka I. N., Hazzan R., Yacovzada N. S., Igbaria S., Segal E., Weinberger A. & Neeman Z. (2025), Scientific Reports. 15, 1, 32035

Stool shed cell transcriptomics mirrors tumor biology and enables colorectal cancer diagnosis

Bahar Halpern K., Kent I., Yakubovsky O., Ben-Moshe S., Barkai T., Fine M., Novoselsky R., Israeli A., Nachmany I. & Itzkovitz S. (2025), Scientific Reports. 15, 1, 34413

Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements

Levy G., Rokach M., Fischer I., Kimchi-Feldhorn O., Shoob S., Bar E., Rosenberg T., Bartman J., Parnas H., Grad M., Israel-Elgali I., Sfadia G. E., Trangle S. S., Vainshtein A., Eisenbach Y. E., Jahn O., Siems S. B., Werner H. B., Shomron N., Assaf Y., Peles E., Slutsky I., Marco A. & Barak B. (2025), Nature Communications. 16, 1, 8518

IceQream: Quantitative chromosome accessibility analysis using physical TF models

Bercovich A., Lifshitz A., Eldar M., Cheng S., Stok Ranen R., Stelzer Y. & Tanay A. (2025), Nature Communications. 16, 1, 8984

IceQream: Quantitative chromosome accessibility analysis using physical TF models

Bercovich A., Lifshitz A., Eldar M., Cheng S., Stok Ranen R., Stelzer Y. & Tanay A. (2025), Nature Communications. 16, 1, 8984

Integrated spatial proteomic analysis of breast cancer heterogeneity unravels cancer cell phenotypic plasticity

Mardamshina M., Karagach S., Mohan V., Arad G., Necula D., Golani O., Fellus-Alyagor L., Shenoy A., Krol K., Pirak D., Itzhacky N., Marin I., Shalmon B., Addadi Y., Sharan R., Gal-Yam E., Barshack I. & Geiger T. (2025), Nature Communications. 16, 1, 10482

Single-cell transcriptomic analysis of HPV-related multiphenotypic sinonasal carcinoma uncovers MYB-HPV association

Wizel A., Spence M. D., Mints M., Britton W., Okolo O., Yu V., Cioffi I., Caruana S., Troob S. H., Faquin W. C., Lin D. T., Tirosh I., Puram S. V., Parikh A. S. & Drier Y. (2025), npj Precision Oncology. 9, 1, 378

Dissecting endometrial cancer complexity in response to standard and targeted therapies

Vaccarella S., Bruno V., Orlandi G., Covino D. A., Frascolla C., Pulito C., Vizza R., Urbani G., Allegretti M., De Pascale V., Goeman F., Ciuffreda L., Arteni B. A. M., Di Martino S., Sacconi A., Mancini E., Bagnato A., Baiocco E., Kajal R., Vinik Y., Lev S., Fanciulli M., Vidiri A., Carosi M., Strano S., Donzelli S., Vizza E. & Blandino G. (2025), Cell Death and Disease. 16, 1, 873

Unifying regulatory motifs in endocrine circuits

Raz M., Glass D. S., Milo T., Korem Kohanim Y., Karin O., Tendler A., Mayo A. & Alon U. (2025), Nature Communications. 16, 1, 11017

MMS22L is a novel key actor of normal and pathological erythropoiesis

Colin E., Ferrer-Vicens I., Brook D., Salma M., Andrieu-Soler C., Bayard E., Fernandes A., Brouzes C., Lefèvre C., Duval R., Dussiot M., Trovati T., Courtois G., Azouzi S., Zarhrate M., Lambilliotte A., Park S., Carpentier B., Colard M., Manceau S., Moshous D., Mayeux P., Gautier E. F., Miccio A., Soulier J., Vainchenker W., Shlush L., Da Costa L., Frayne J., Soler E., Hermine O. & Couronné L. (2025), HemaSphere. 9, 12, e70264

Sirt6 prevents the age-related decline of H2S through the control of one-carbon metabolism

Touitou N., Nahum L., Feldman-Trabelsi S., Avivi M. Y., Aon M. A., Naiman S., Rathaus M., Gertler A. A., Roichman A., Dvir L. B., Bernier M., Banskota N., Beck L., Nagar R., Schwartz Z., Price N. L., Harel M., Lerrer B., Ishii I., Senderowitz H., Moaddel R., Geiger T., de Cabo R. & Cohen H. Y. (2025), Proceedings of the National Academy of Sciences of the United States of America. 122, 46, e251408412

Characterization of the tumor microbiome of brain metastases and glioblastoma reveals tumor-type-specific and location-specific microbial signatures

Gigi E., Gavert N., Raijman-Nagar L., Zwang Y., Zemach H., Livyatan I., Levy-Barda A., Laviv Y., Kanner A. A., Amiel A., Siegal T., Leibovici A., Selezen I., Badran O., Zohar Y., Safadi E., Prather L. L., Helfer C. R., Castro P., Barshack I., Dadosh T., Levin-Zaidman S., Goliand I., Golani O., Horn S., Mandel J. J., Shental N., Shai A., Yust-Katz S. & Straussman R. (2025), Nature Cancer. 6, 11, p. 1761-1776

Open problems in ageing science: a roadmap for biogerontology

Talay A., Belikov A. V., To P. K. P., Alfatemi H. H., Alon U., Deelen J., Ewald C. Y., Gems D., Gorbunova V., Gruber J., Hägg S., Hemming J., Horvath S., Kaya A., Lewis C. J., Maier A. B., Marinova M. B., Pawelec G., Peleg S., Rattan S., Scheibye-Knudsen M., Schmauck-Medina T., Saroyan V., Seluanov A., Stolzing A., Teeling E., Williams R. W., White T., Unfried M. & de Magalhães J. P. (2025), GeroScience

A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology

Azulay N., Milo I., Bussi Y., Ben-Uri R., Haran T. K., Eldar M., Elhanani O., Harnik Y., Yakubovsky O., Nachmany I., Salame T., Wartenberg M., Bertheau P., Michonneau D., Socie G. & Keren L. (2025), Science Translational Medicine. 17, 823, eadu6032

p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer

Aylon Y., Furth N., Pirona A. C., Lavie A., Fedorova O., Hassin O., Padrão N., Steinmetz M., Sarusi-Potuguez A., Fellus-Alyagor L., Shimoni I., Dassa B., Zwart W., Shema E. & Oren M. (2025), Proceedings of the National Academy of Sciences - PNAS. 122, 44, e252264612

Aged B cells as a candidate cell of origin for diffuse large B cell lymphoma: A multi-modal analysis of somatic mutation, clonality, and transcriptional programs

Dadi G., Varon B., Naffaa M., Feldman T., Horowitz N., Kaushansky N. & Shlush L. (2025), Blood. 146, Supplement 1, p. 461-462

Deciphering the origin and plasticity of circulating endothelial cells reveals a systemic angiogenic program in breast cancer

Efros O., Brook D., Elkahal J., Furer N., Dadi G., Yaniv Y., Naor H., Rappoport N., Milman O., Tavor S., Kaushansky N., Tzahor E., Yaniv K., Tanay A. & Shlush L. (2025), Blood. 146, Supplement 1, p. 1324

Deciphering the origin and plasticity of circulating endothelial cells reveals a systemic angiogenic program in breast cancer

Peripheral blood-based single-cell and genomic profiling of hematopoietic stem and progenitor cells enables accurate diagnosis and risk stratification in myeloproliferative neoplasms

Dadi G., Milman O., Saar-Furer N., Duek A., Tavor S., Shlush L. & Tanay A. (2025), Blood. 146, Supplement 1, p. 5532

Peripheral blood-based single-cell and genomic profiling of hematopoietic stem and progenitor cells enables accurate diagnosis and risk stratification in myeloproliferative neoplasms

Dadi G., Milman O., Saar-Furer N., Duek A., Tavor S., Shlush L. & Tanay A. (2025), Blood. 146, Supplement 1, p. 5532

ProtoMol: enhancing molecular property prediction via prototype-guided multimodal learning

Wang Y., Zhang K., Huang J., Yin N., Liu S. & Segal E. (2025), Briefings in Bioinformatics. 26, 6, bbaf629

Artificial intelligence in metabolic research

Holst J. J., Scheele C., Scherer P. E., Jia W., Segal E., Slavov N., Loos R. J. F., Vahedi G., Sun L., Babu M. M., McCradden M. D. & Jacobs P. G. (2025), Nature Metabolism. 7, 11, p. 2183-2186

Evolutionarily conserved role of oxytocin in zebrafish social reward encoding

Kareklas K., Herrera-Castillo L., Levkowitz G. & Oliveira R. F. (2025), Biology Letters. 21, 11, 20250628

Deciphering the spatial architecture of transcriptional heterogeneity in glioblastoma at single cell resolution

Mount C., Wen Z., Greenwald A., Kovatsis S., Lu J., Gerovasilis D., Tirosh I. & Suva M. (2025), Neuro-Oncology. 27, Supplement_5, p. v461

Evaluating cell state-targeting CAR-T cells in glioblastoma

Kovatsis S., Mount C., Boxer E., Zhong J., Dumont S., Gerovasilis D., Lu J., Tirosh I. & Suva M. (2025), Neuro-Oncology. 27, Supplement_5, p. v347

Mutant IDH silences GSX2 to reprogram neural progenitor cell fate and promote gliomagenesis

Xiao Y., Shi D., Guo L., Neumann E., Levitt M., Kaphle P., Shipman T., Li H., Cai F., Ramirez D., Zacharias L., Chen Z., Lin M., Thidil V., Mathews T., Mishra P., Kim Y. J., Xu J., Mack S., Deberardinis R., Tirosh I., Suva M., Xu L., Abdullah K. & Mcbrayer S. (2025), Neuro-Oncology. 27, Supplement_5, p. v434

Developing cell-state guided chimeric antigen receptor (CAR)-T cell therapies for IDH-mutant glioma

Dumont S., Mount C., Gerovasilis D., Kovatsis S., Lu J., Zhong J., Boxer E., Cahill D., Tirosh I. & Suva M. (2025), Neuro-Oncology. 27, Supplement 5, p. v357

Vagal blockade of the brain-liver axis deters cancer-associated cachexia

Garrett A., Darzi N., Deshmukh A., Rosenfeld N., Goldman O., Adler L., Bab-Dinitz E., Singer O., Hassani Najafabadi A., Wong C. W., Bose S., Randon P. M., Bustamante F., Larios R., Brandis A., Mehlman T., Smaglo B., Chang P., Oliva J., Haymaker C., Nagawekar L., Wu S. R., Huang Y., Shen A., Vora A., Padilla J. F., Pfeffer A., Sutherland G., Starr M., Zimmers T., Zhu Y., Morizio J., Erez A. & Shen X. (2025), Cell. 188, 21, p. 6044-6063.e24

CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging

Elyahu Y., Feygin I., Eremenko E., Pinkas N., Zemer A., Shicht A., Berner O., Avigdory-Meiri R., Nemirovsky A., Reshef K., Roitman L., Krizhanovsky V. & Monsonego A. (2025), Nature Aging. 5, 10, p. 1970-1982

Challenges and Opportunities in Spatiotemporal Models of Mammalian Gastrulation

Rubinstein H., Mayshar Y. & Stelzer Y. (2025), Annual Review of Cell and Developmental Biology. 41, 1, p. 135-158

PNKP targeting engages the autophagic machinery through STING and STAT3 to potentiate ferroptosis and chemotherapy in TNBC

Maimon A., Puzzovio P. G., Vinik Y., Hannuna G. D., Donzelli S., Rutigliano D., Blandino G. & Lev S. (2025), Redox Biology. 86, 103775

Cell State Targeting Car T Cell Therapies for Idh Mutant Gliomas

Mount C., Dumont S., Gerovasilis D., Boxer E., Kovatsis S., Lu J., Zhong J., Cahill D., Tirosh I. & Suva M. (2025), Neuro-Oncology. 27, Supplement 3

A Non-Canonical role of cGMP Links PDE5A Inhibition to Metastasis Suppression

Ariav Y., Hayek S., Darzi N., Ray L., Ben-zeev E., Malitsky S., Goliand I., Ruppin E. & Erez A. (2025), Molecular Cancer Therapeutics. 24, 10, C118

Schwannomas Display Conserved Cellular States and Preferential Mhc Class Ii Antigen Presentation Across Different Genetic Backgrounds and Anatomic Locations

Gonzalez Castro L., Gavish A., Bussema L., Mount C., Neftel C., Nomura M., Chiocca E., Bi W., Arnaout O., Barker F., Brown J., Jordan J., Batchelor T., Stemmer-Rachamimov A., Plotkin S., Tirosh I. & Suva M. L. (2025), Neuro-Oncology. 27, Supplement 3, p. iii142

Phenotypic, Microenvironmental, and Genetic Crosstalk Shapes Pancreatic Cancer Organization

Elhanani O., Truzman G., Wartenberg M., Bussi Y., Shainshein D., Engelberg B., Harlev I., Lilien A., Zlobec I., Geiger T. & Keren L. (2025), Cancer Research. 85, 18, p. B123

Phenotypic, Microenvironmental, and Genetic Crosstalk Shapes Pancreatic Cancer Organization

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The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution

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Long-term Hyperbaric Oxygen Treatment Enhances Nerve Regeneration and Remyelination in a Rat Sciatic Nerve Graft Model

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RNA editing deficiency models differential immunogenicity of pancreatic α- and β-cells

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Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing

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Mapping circulating hematopoietic stem cells for non-invasive, blood-based diagnostics

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A reference model of circulating hematopoietic stem cells across the lifespan with applications to diagnostics

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A reference model of circulating hematopoietic stem cells across the lifespan with applications to diagnostics

Baseline Characteristics of Weight-Loss Success in a Personalized Nutrition Intervention: A Secondary Analysis

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From bench to business: translating academic advances into industry innovations

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The Society for Immunotherapy of Cancer Perspective on Liquid Biopsy and Radiomics-Based Technologies for Immuno-oncology Biomarker Discovery and Application

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Curating a single-cell data atlas for a deeper understanding of intra-tumor heterogeneity

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Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice

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Erratum: Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma (Cancer Cell (2021) 39(6) (779792.e11), (S1535610821002683), (10.1016/j.ccell.2021.05.002))

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Characterizing the metabolome of children with growth hormone deficiency

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Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimers Disease

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Translation dysregulation in cancer as a source for targetable antigens

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The Curated Cancer Cell Atlas provides a comprehensive characterization of tumors at single-cell resolution

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Proteomic and lipidomic analysis of low-density lipoprotein identifies potential biomarkers of early estrogen receptor-positive breast cancer

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Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC

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Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics

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GMP-like and MLP-like Subpopulations of Hematopoietic Stem and Progenitor Cells Harboring Mutated EZH2 and TP53 at Diagnosis Promote Acute Myeloid Leukemia Relapse: Data of Combined Molecular, Functional, and Genomic Single-Stem-Cell Analyses

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ARID5A promotes inflammation and fibrosis during cardiac aging: Cardiac aging

Miyara S. & Tzahor E. (2025), Nature Cardiovascular Research. 4, 5, p. 508-510

Development of antibiotic resistome in premature infants

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Deciphering the complex clonal heterogeneity of polycythemia vera and the response to interferon alfa

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Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse

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Preventing Multimer Formation in Commonly Used Synthetic Biology Plasmids

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End-User Confidence in Artificial Intelligence-Based Predictions Applied to Biomedical Data

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Metabolic interplays between the tumour and the host shape the tumour macroenvironment

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Clinical translation of microbiome research

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Pregnancy and postpartum dynamics revealed by millions of lab tests

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Cold and hot fibrosis define clinically distinct cardiac pathologies

Hormone circuit explains why most HPA drugs fail for mood disorders and predicts the few that work

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Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma

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Phenome-wide associations of sleep characteristics in the Human Phenotype Project

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Submitted Version

Members of the DIP and Dpr adhesion protein families use cis inhibition to shape neural development in Drosophila

Morano N. C., Lopez D. H., Meltzer H., Sergeeva A. P., Katsamba P. S., Rostam K. D., Gupta H. P., Becker J. E., Bornstein B., Cosmanescu F., Schuldiner O., Honig B., Mann R. S. & Shapiro L. (2025), PLoS Biology. 23, 3, e3003030

Emerging clinical applications of single-cell RNA sequencing in oncology

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What is the main bottleneck in deriving biological understanding from spatial transcriptomic profiling?

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Editorial A Journal that Promotes Excellence Through Uncompromising Review Process: Reflection of freedom of speech and scientific publication

Kam Z. & Nicora G. (2025), International Journal of Neural Systems. 35, 13, 2502001

The Society for Immunotherapy of Cancer Perspective on Tissue-Based Technologies for Immuno-Oncology Biomarker Discovery and Application

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International consensus statement on microbiome testing in clinical practice

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GD3 ganglioside checkpoints in immune surveillance of senescent cells: Immune surveillance

Majewska J. & Krizhanovsky V. (2025), Nature Aging. 5, 2, p. 182-183, 5435

Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer

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Oncogenic IDH1mut drives robust loss of histone acetylation and increases chromatin heterogeneity

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