Systems Medicine 2019
- Lecture Notes and exercises
- Lecture 1 - The lnsulin-glucose circuit.
- Lecture 2 - Beta-cell tissue size control has fragilities that lead to type-2 diabetes: Dynamical compensation and mutant resistance in tissues.
- Exercise 1
- Lecture 3 - Autoimmune disease as a fragility of surveillance against hypersecreting mutants.
- Lecture 4 - Two-gland feedback in the stress-hormone axis generates seasonal clocks and explains clinical phenomena with a timescale of months.
- Exercise 2
- Lecture 5 - The basic facts of ageing.
- Lecture 6 - Aging and the saturation of damage removal
- Exercise 3
- Lecture 7 - Aging-related diseases and their exponentially rising incidence with age
- Lecture 8 - Inflammation and fibrosis as a bistable system
- Exercise 4
- Lecture 9 - Evolutionary tradeoffs, division of labor in tissues, and Universal cancer tasks
- Lecture 10 - The growth axis, catch-up growth and mini growth spurts
- Lecture 11 - Major depression and the slow timescale of treatment
- Exercise 5
- Lecture 12 - Addiction
