Prefrontal cortex in goal-directed behavior
The prefrontal cortex is extremely heterogeneous in its neuronal subtypes, their interactions with other brain regions and their connectivity within the local circuit. We are interested in the contribution of prefrontal neuron populations to the performance of goal-directed behaviors. We use electrophysiological recordings in behaving mice, optogenetic manipulations, calcium imaging and advanced photometry to dissect the dynamic involvement of these neurons in behavior.