The African clawed frog (Xenopus laevis) is a species of African aquatic frog. Its name is derived from the three short claws on each hind foot, as the word Xenopus means "strange foot".
Xenopus has long been an important tool for in vivo studies in molecular, cell, and developmental biology of vertebrate animals. However, the wide breadth of Xenopus research stems from the additional fact that cell-free extracts made from Xenopus are a premier in vitro system for studies of fundamental aspects of cell and molecular biology. Thus, Xenopus is the only vertebrate model system that allows for high-throughput in vivo analyses of gene function and high-throughput biochemistry. Finally, Xenopus oocytes are a leading system for studies of ion transport and channel physiology.
The Xenopus unit
The unit is located at Herzberg building.
The colony includes about 50 adult female xenopus leavis for oocytes production.
Xenopus are being housed in recirculating systems in which water recirculates through mechanical, biological, and chemical filters and UV lights. 10% of the water is removed daily. The systems include 24 tanks, 27 liter each, in two racks.
Reverse Osmosis water is being supplemented automatically by dosing pumps with salts and sodium bicarbonate to reach conductivity of 1200µS and pH of 7.5. The water temperature is being kept at 18°C.
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