| 9:00 |
Opening remarks |
| Session 1: Evolution (Chair - Ilan Samish) |
| 9:05 |
Nick V. Grishin. Dramatic Evolutionary Changes in Protein Structures. (Invited Presentation) |
| 9:35 |
Sandra Maguid, Gustavo Parisi, Sebastian Fernandez-Alberti, Julian Echave. Sequence-structure-flexibility relationship in protein evolution. (more) |
| 9:55 |
Maria S. Fornasari, Gustavo Parisi. Protein Structure Diversity and Sequence Divergence in Evolution. (more) |
| 10:15 |
Diana K Ekman, Åsa K Björklund, Arne Elofsson. Evolutionary History of Multi-Domain Proteins. (more) |
10:35 | Coffee Break |
| 11:05 |
Christopher Dupont, Song Yang, Brian Palenik, Philip E. Bourne. Modern Proteomes Contain Imprints of Ancient Shifts in Environmental Chemistry. (invited presentation) |
| Session 2: Homology Modeling (Chair - Nick Grishin) |
| 11:35 |
Francisco Melo, Alejandro Panjkovich, Andrej Sali, Marc A. Marti-Renom. Structure Specific Statistical Potentials for Protein Structure Prediction. (more) |
| 11:55 |
Iris Antes, Thomas Lengauer. DynaDock: Inhibitor based Refinement of Homology Modeled Protein Structures for Molecular Docking. (more) |
12:15 | Lunch and Laptop Session
1 |
| 15:00 |
Discussion 1: The roles of Evolution, physics and informatics (Chair - Phil Bourne). |
| Session 3: Ligand Binding (Chair - Phil Bourne) |
| 15:45 |
Rafael J. Najmanovich, Richard J. Morris, Janet M. Thornton. Single-Family Analysis of Binding Site Structural Similarities. (more) |
| 16:05 |
Thomas Funkhouser, Roman Laskowski, Janet Thornton. Matching Volumetric Models of Protein Active Sites. (more) |
| 16:25 |
Melissa R. Landon, Spencer C. Thiel, David R. Lancia Jr., Sandor Vajda. Identification of Druggabable "Hot Spots" in Ligand Binding Pockets by Computational Solvent Mapping of Proteins. (more) |
16:45 | Coffee Break |
| Session 4: Model Quality (Chair - John Moult) |
| 17:15 |
Michal J. Gajda, Marta Kaczor, Janusz M. Bujnicki, Anastasia Bakulina, Andrzej Kasperski, Alan M. Friedman, Chris Bailey-Kellogg. FILTREST3D: a Simple Method for Discrimination of Multiple Structural Models Against Spatial Restraints. (more) |
| 17:35 |
Marcin Pawlowski, Janusz Bujnicki, Ryszard Matlak. Meta-MQAP: an SVM-based meta-server for the quality assessment of protein models. (more) |
| 17:55 |
Wah Chiu, Matthew L Baker. Modeling Protein Components of Biological Nano-Machines in Subnanometer Resolution CryoEM Density Maps. (invited presentation) |
18:25 |
Break: Busses to evening session |
20:00 |
Get-together Dinner at main headquarters hotel (Oasis Atlantic Hotel). |
21:00 |
John Moult. CASP: Progress, Bottlenecks, Prognosis, and Messages for Computational Biology. |
23:00 | Lights out... |
Top |
Day 2 |