Selected Publications

• Shelly Rozen, Alessandra Tieri, Gabriela Ridner, Ann-Kathrin Stark, Tilo Schmaler, Gili Ben-Nissan, Wolfgang Dubiel and Michal Sharon.
  Exposing the subunit diversity within protein complexes: A mass spectrometry approach
  Methods, (2013), in press.

• Peter Tsvetkov, Nadav Myers, Oren Moscovitz, Michal Sharon, Jaime Prilusky and Yosef Shaul.
  Thermo-resistant intrinsically disordered proteins are efficient 20S proteasome substrates.
  Mol. BioSyst., 8:368-373 (2012).

• Oren Moscovitz, Peter Tsvetkov, Nimrod Hazan, Izhak Michaelevski, Hodaya Keisar, Gili Ben-Nissan, Yosef Shaul and Michal Sharon.
  A Mutually Inhibitory Feedback Loop between the 20S Proteasome and Its Regulator, NQO1.
  Molecular Cell, 47:76-86 (2012).

• Michal Sharon and Carol V. Robinson.
  Peeling back the layers of complexity.
  Current Opinion in Structural Biology, 21:619-621 (2011).

• Michal Sharon and Carol V. Robinson.
  A Quantitative Perspective on Hydrophobic Interactions in the Gas-Phase.
  Current Proteomics, 8:47-58 (2011).

• Gili Ben-Nissan and Michal Sharon.
  Capturing protein structural kinetics by mass spectrometry.
  Chem Soc Rev, May 6 (2011) .

• Izhak Michaelevski, Miriam Eisenstein and Michal Sharon.
  Gas-Phase Compaction and Unfolding of Protein Structures.
  Anal. Chem., 82(22):9484–9491(2010).

• Liat Shimon, Michal Sharon and Amnon Horovitz.
  A Method for Removing Effects of Nonspecific Binding on the Distribution of Binding Stoichiometries: Application to Mass Spectroscopy Data.
  Biophys J., 99(5):1645-1649(2010).

• Laura B. Sheard, Xu Tan, Haibin Mao, John Withers, Gili Ben-Nissan, Thomas R. Hinds, Yuichi Kobayashi,Fong-Fu Hsu, Michal Sharon, John Browse, Sheng Yang He, Josep Rizo, Gregg A. Howe & Ning Zheng.
  Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor.
  Nature, 468(7322):400-405(2010).

• Sharon M.
  How far can we go with structural mass spectrometry of protein complexes?
  J Am Soc Mass Spectrom., 21: 487–500 (2010).

• Itamar Yadid, Noam Kirshenbaum, Michal Sharon, Orly Dym, and Dan S. Tawfik.
  Metamorphic proteins mediate evolutionary transitions of structure.
  PNAS, 107 (16):7287–7292 (2010),

• Kirshenbaum N, Michaelevski I, Sharon M.
  Analyzing large protein complexes by structural mass spectrometry.
  J Vis Exp., 40: (2010). (Download and view movie, please be patient.)

• Izhak Michaelevski, Noam Kirshenbaum, Michal Sharon.
  T-wave ion mobility-mass spectrometry: basic experimental procedures for protein complex analysis.
  J Vis Exp., (2010). (Download and view movie, please be patient.)

• Kfir Gazit, Sandra Moshonov, Rofa Elfakess, Michal Sharon, Gabrielle Mengus, Irwin Davidson, and Rivka Dikstein.
  TAF4/4b_TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.
  J.Biol. Chem., 284 (39): 26286-26296 (2009).

• Sharon,M., Mao,H., Boeri Erba,E., Stephens,E., Zheng,N. and C. V. Robinson.
  Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality.
  Structure, 17:31-40(2009).

• Andersson,F.I., Tryggvesson,A., Sharon,M., Diemand,V.D., Classen,M., Best,C., Schmidt,R., Schelin,J., Stanne,T.M., Bukau,B., Robinson, C.V., Witt,S., Mogk, M. and A.C. Clarke.
  Structure and function of a novel type of ATP-dependent Clp protease.
  J.Biol. Chem., 284 (20): 3519–13532 (2009).

• Sharon, M., Ilag, L. L. and C. V. Robinson.
  Evidence for micellar structure in the gas phase.
  J. Am. Chem. Soc., 129(28):8740-6 (2007).

• Sharon, M., Witt, S., Glasmacher, E., Baumeister, W. and C. V. Robinson.
  Mass spectrometry reveals the missing links in the assembly pathway of the bacterial 20S proteasome.
  J. Biol. Chem., 282(25):18448-57 (2007).

• Sharon, M. and C. V. Robinson.
  The Role of Mass spectrometry in the analysis of protein complexes.
  Annu. Rev. Biochem., 76:167-93 (2007).

• Tan, X., Calderon-Villalobos, L. I. A., Sharon, M., Zheng C., Robinson C. V., Estelle, M. and N. Zheng.
  Mechanism of auxin perception by the TIR1 ubiquitin ligase.
  Nature, 446(7136):640-5 (2007).

• Frenkiel-Krispin, D., Grayer-Wolf, S., Albeck, S., Unger, T., Peleg, Y., Daube, S., Sharon, M., Svergun, D. I., Robinson, C. V., Tzfira, T. and M. Elbaum.
  Plant transformation by Agrobacterium tumefaciens: Regulation of ssDNA-VirE2 complex assembly by VirE1.
  J. Biol. Chem., 282(6):3458-64 (2006).

• Medalia, N., Sharon, M., Martinez-Arias, R., Mihalache, O., Robinson, C. V., Medalia, O. and P. Zwickl.
  Functional and structural characterization of the Methanosarcina mazei proteasome and PAN complexes.
  J. Struc. Biol., 156(1):84-92 (2006).

• Sharon, M., Taverner, T., Ambroggio, X. I., Deshaies, R. J. and C. V. Robinson.
  Structural organization of the 19S proteasome lid: Insights from MS of intact complexes.
  PLoS Biol., 4(8):e267 (2006).

• Witt, S., Kwon Y. D., Sharon, M., Felderer, K., Robinson, C. V., Baumeister, W. and B. K. Jap.
  Proteasome assembly triggers a switch required for active site maturation.
  Structure, 14(7):1179-88 (2006).

• Sharon, M., Witt, S., Felderer, K., Rockel, B., Baumeister, W. and C. V. Robinson.
  20S proteasomes have the potential to keep substrates in store for continual degradation.
  J. Biol. Chem., 281(14):9569-75 (2006).