Publications

  1. Unger-Angel L, Motiei L, Margulies D (2019). Molecular Logic as a Means to Assess Therapeutic Antidotes.  Frontiers in Chemistry. 2019, 7 :243.
    • "Rising Stars" article collection
  2. Lustgarten O, Carmieli R, Motiei L, Margulies D (2019). A Molecular Secret Sharing Scheme.  Angew. Chem. Int. Ed. 2019, 58 :184-188.
  3. Pode Z, Peri-Naor R, Georgeson J. M, Ilani T, Kiss V, Unger T, Markus B, Barr H. M, Motiei L, Margulies D (2017). Protein Recognition by a Pattern-Generating Fluorescent Molecular Probe.  Nature Nanotechnol. 2017, 12 :1161–1168.
  4. Lustgarten O, Motiei L, Margulies D (2017). User Authorization at the Molecular Scale.  ChemPhysChem. 2017, 18 :1678-1687.
    • VIP paper
  5. Hatai J, Motiei L, Margulies D (2017). Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor.  J. Am. Chem. Soc. 2017, 139 :2136-2139.
  6. Nissinkorn Y, Motiei L, Margulies D (2016). Protein Surface Recognition with Targeted Fluorescent Molecular Probes.  Receptors Clin. Investig. 2016, 3 : e1381.
    • Invited highlight article
  7. Sarkar T, Selvakumar K, Motiei L, Margulies D (2016). Message in a Molecule.  Nature Commun. 2016, (7) :11374.
  8. Peri-Naor R, Motiei L, Margulies D (2016). Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy.  J. Vis. Exp. 2016, 115 :e54396.
    • Invited paper
  9. Selvakumar K, Motiei L, Margulies D (2015). Enzyme-Artificial Enzyme Interactions as a Means for Discriminating among Structurally Similar Isozymes.  J. Am. Chem. Soc. 2015, 137 :4892-4895.
  10. Guez-Haddad J, Sporny M, Sasson Y, Gevorkyan-Airapetov L, Lahav-Mankovski N, Margulies D Radzimanowski J, Opatowsky Y (2015). The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism .  Structure. 2015, 23 :1989-2000.
  11. Peri-Naor R, Motiei L, Margulies D (2015). Artificial Signal Transduction Therapy: A Futuristic Approach to Disease Treatment.  Future Med. Chem. 2015, 7 :2091-2093.
    • Invited editorial paper (special issue: chemical biology spotlight)
  12. Nissinkorn Y, Lahav-Mankovski N, Rabinkov A, Albeck S, Motiei L, Margulies D (2015). Sensing Protein Surfaces with Targeted Fluorescent Receptors.  Chem. Eur. J. 2015, 21 :15981–15987 .
  13. Unger-Angel L, Rout B, Ilani T, Eisenstein M, Motiei L, Margulies D (2015). Protein Recognition by Bivalent, ‘Turn-On’ Fluorescent Molecular Probes.  Chem. Sci. 2015, 6 :5419-5425.
  14. Peri-Naor R, Ilani T, Motiei L, Margulies D (2015). Protein-Protein Communication and Enzyme Activation Mediated by a Synthetic Chemical Transducer.  J. Am. Chem. Soc. 2015, 137 :9507-9510.
  15. Motiei L, Pode Z, Koganitsky A, Margulies D (2014). Targeted Protein Surface Sensors as a Tool for Analyzing Small Populations of Proteins in Biological Mixtures.  Angew. Chem. Int. Ed. 2014, 53 :9289-9293.
  16. Rout B, Motiei L, Margulies D (2014). Combinatorial Fluorescent Molecular Sensors: The Road to Differential Sensing at the Molecular Level.  Synlett. 2014, 25 :1050-1054.
    • Invited Synpacts prospect article
  17. Rout B, Milko P, Iron MA, Motiei L, Margulies D (2013). D. Authorizing Multiple Chemical Passwords by a Combinatorial Molecular Keypad Lock.  J. Am. Chem. Soc . 2013, 135 :15330–15333.
    • Featured in phys.org.
    • highlighted in SYNPACTS.
  18. Rout B, Unger L, Armony G, Iron MA, Margulies D (2012). Medication Detection by a Combinatorial Fluorescent Molecular Sensor.  Angew. Chem. Int. Ed. 2012, 51 :12477-12481.
    • Feature on the back cover
    • Highlighted by faculty of 1000
    • Highlighted in SYNPACTS
  19. Margulies D, Hamilton AD (2010). Combinatorial Protein Recognition as an Alternative Approach to Antibody-Mimetics.  Curr. Opin. Chem. Biol. 2010, 14 :705-712.
  20. Margulies D, Hamilton AD (2009). Protein Recognition by an Ensemble of Fluorescent DNA G-Quadruplexes.  Angew. Chem. Int. Ed. 2009, 48 :1771-1774.
    • Selected as a "Hot Paper" by the editors.
    • Highlighted in Nat. Chem. 2009, 1, 20-21.
  21. Margulies D, Hamilton AD (2009). Digital Analysis of Protein Properties by an Ensemble of DNA Quadruplexes.  J. Am. Chem. Soc. 2009, 131 :9142–9143 .
  22. Margulies D, Opatowsky Y, Fletcher S, Saraogi I, Tsou K, Saha S, Schlessinger J, Hamilton AD (2009). Surface Binding Inhibitors of the SCF-KIT Protein- Protein Interaction.  ChemBioChem. 2009, 10 :1955-1958.
  23. Margulies D, Felder CE, Melman G, Shanzer A (2007). A Molecular Keypad Lock: A Photochemical Device Capable of Authorizing Password Entries.  J. Am. Chem. Soc. 2007, 129 :347-354.
    • Selected by the ACS office of communications science writers as one of five first-of-their-kind        discoveries among the 30,000 ACS papers published in 2007
    • Highlighted in Angew. Chem. Int. Ed. 2007, 46, 5472-5475.
    •  Highlighted in RSC Chemistry World News (January 2007)
  24. Margulies D, Melman G, Shanzer A (2006). A Molecular Full-Adder and Full-Subtractor, an Additional Step toward a Moleculator.  J. Am. Chem. Soc. 2006, 128 :4865-4871.
    •  Highlighted in Nature 2006, 440, 719.
  25. Margulies D, Melman G, Shanzer A (2005). Fluorescein as a Model Molecular Calculator with Reset Capability.  Nat. Mater. 2005, 4 :768-771.
    • Among Nature editors' choices of chemistry papers from NPG journals from 2005-2006 at the ACS spring meeting 2006.
  26. Margulies D, Melman G, Felder CE, Arad-Yellin R, Shanzer A (2004). Chemical Input Multiplicity Facilitates Arithmetical Processing.  J. Am.Chem. Soc. 2004, 126 :15400-15401.
    • Highlighted in Nature. Mater. 2005, 4, 15-16.
  27. Ashkenasy G, Margulies D, Felder CE, Shanzer A, Powers LS (2002). Bidentate Ligation of Heme Analogues; Novel Biomimetics of the Peroxidase Active Site.  Chem. Eur. J. 2002, 8 :4017-4026.