Specifically, the arginine on ring I, conjugated via the aliphatic amine of neomicyn B, is positioned in the cavity form by the bulge of TAR-RNA. The interaction of the a-amino group of the arginine with the phosphates is indicated.

The structure of the TAR-RNA is based on the structure of the TAR-RNA-arginineamide complex (PDB entry 1arj).

This file was last modified on Monday, 25-Dec-2000 16:43:15 IST.