In collaboration with Z. Kam an advanced system for automated quantitative microscopy was developed and applied for several screening projects, including discovery of novel adhesion proteins and search for modulators of p53 distribution and action (Irina Lavelin, Victoria Simchaev), screening for cytoskeleton modulating genes and compounds, and establishment of automated morphometric scoring (Yael Paran), migration screens (Suha Naffar Abu-Amara), and examination of siRNA effects (Sabina Winograd-Katz). In these screens a wide variety of reporter cells are used, and special image processing software is tailored for each project.
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