Publications

Selected publications (see pubmed for full list)

*- Equal first-authors; # - Corresponding author

2017

  • Puram S*, Tirosh I*# et al. (in press). “Single-cell RNA-seq reveals malignant and stromal programs associated with metastasis in head and neck cancer”. Cell
  • Venteicher A*, Tirosh I*#, Hebert C, Yizhak K, Neftel C, Filbin MG, Escalante L, Shaw M, Rodman C, Nahed B, Cahill D, Curry W, Martuza R, Mylvaganam R, Iafrate J, Frosch M, Golub T, Rivera M, Patel A, Rozenblatt-Rosen O, Getz G, Bernstein B, Louis D, Regev A, Suvà M (2017). “Decoupling genetic, developmental and micro-environmental programs in IDH-mutant gliomas through single-cell transcriptomics”. Science 355(6332). [PDF]

2016

  • Tirosh I*, Venteicher A*, Hebert C, Escalante L, Patel A, Yizhak K, Fisher J, Desai N, Rodman C, Luo C, Francis J, Mount C, Onozato M, Riggi N, Livak K, Filbin M, Gennert D, Satija R, Nahed B, Cahill D, Curry W, Martuza R, Mylvaganam R, Iafrate J, Frosch M, Golub T, Rivera M, Rozenblatt-Rosen O, Getz G, Monje M, Bernstein B, Louis D, Regev A, Suvà M (2016). "Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma." Nature 539(7628):309-313. [PDF]
  • Tirosh I*, Izar B*, Prakadan S, Wadsworth M, Treacy D, Trombetta J, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin J, Cohen O, Shah P, Lu D, Genshaft A, Hughes T, Ziegler C, Kazer S, Gaillard A, Kolb K, Villani A, Johannessen C, Andreev A, Van Allen E, Bertagnolli M, Sorger P, Sullivan R, Flaherty K, Frederick D, Jané-Valbuena J, Yoon C,  Rozenblatt-Rosen O, Shalek A, Regev A and Garraway L (2016). "Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq." Science 352(6282): 189-196. [PDF]

2015

  • Kowalczyk MS*., Tirosh I*, D. Heckl, T. N. Rao, A. Dixit, B. J. Haas, R. K. Schneider, A. J. Wagers, B. L. Ebert and A. Regev (2015). "Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells." Genome Res 25(12): 1860-1872. [PDF]

2014

  • Patel AP*., Tirosh I*, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suva ML, Regev A and Bernstein BE (2014). "Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma." Science 344(6190): 1396-1401. [PDF]