Publications

Selected recent publications (see pubmed for full list)

*- Equal first-authors; # - Corresponding author

2019

  • Neftel C, Laffy J et al. (2019) An integrative model of cellular states, plasticity and genetics for glioblastoma. Cell 178:1–15. [PDF

  • Suvà ML, Tirosh I# (2019). “Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges”. Mol Cell. 2019 Jul 11;75(1):7-12. [PDF]

  • Keskin DB*, Anandappa AJ*, Sun J*, Tirosh I*, et al. (2019). “Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial”. Nature 565(7738):234-239. [PDF]

  • Tirosh I#, Suva ML (2019). “Deciphering Human Tumor Biology by Single-Cell Expression Profiling”. Annual Reviews Cancer Biology Vol. 3. [PDF]

2018

  • Filbin MG*, Tirosh I*, Hovestadt* et al. (2018). “Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq”. Science 360(6386): 331-335. [PDF]

2017

  • Puram S*, Tirosh I*#et al. (2017). “Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer”. Cell 171(7):1611-1624. [PDF]    

  • Venteicher A*, Tirosh I*#et al.  (2017). “Decoupling genetic, developmental and micro-environmental programs in IDH-mutant gliomas through single-cell transcriptomics”. Science 355(6332). [PDF]

2016

  • Tirosh I*, Venteicher A*, et al. (2016). "Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma." Nature 539(7628):309-313. [PDF]

  • Tirosh I*, Izar B* et al. (2016). "Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq." Science 352(6282): 189-196. [PDF]

2015

  • Kowalczyk MS*., Tirosh I* et al. (2015). "Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells." Genome Res 25(12): 1860-1872. [PDF]

2014

  • Patel AP*., Tirosh I* et al. (2014). "Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma." Science 344(6190): 1396-1401. [PDF]