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RNA is modified by >100 chemical modifications. These modifications are, in some cases, highly ubiquitous, conserved and dynamically regulated in mRNA, imposing a unique and uncharacterized regulatory code. Our lab aims to crack this code, and understand how modifications on mRNA direct gene expression programs and cell state decisions. Our lab bridges experimental and computational aspects of biological research, combining genomic, genetic and biochemical approaches with tailored computational ones.

News & Announcements

10 August 2019

A commentary about the MAZTER-seq paper was published in the Weizmann Institute magazine

25 July 2019

Miguel and Sarit's paper describing a novel method for quantitative, single-nucleotide detection of m6A, was published.

14 June 2018

Aldema is the recipient of the Weizmann Abroad Postdoc Grant for Advancing Women in Science

20 November 2017

A commentary about our recent paper was published in the Weizmann Institute magazine.

9 November 2017

Modi's paper providing single base resolution maps of the M1A modification is out there.

25 October 2017

Congratulations to Schragi for being elected an EMBO Young Investigator