View description
Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YBR274W
    below threshold
    15.66
  • N' NOP1pr-GFP in SD
    YBR274W
    cytosol,nucleus
    87.6084
  • N' TEF2pr-mCherry in SD
    YBR274W
    nucleus
    85.1196
  • N' NATIVEpr-GFP in SD
    YBR274W
    below threshold
    20.214
  • N' TEF2pr-VC and Cyto-VN in SD
    YBR274W
    cytosol
    33.3008
  • C’ GFP library in SD+DTT 
    YBR274W
    cytosol
    19.37
    1.23
    No
  • C’ GFP library in SD+H2O2
    YBR274W
    cytosol
    18.75
    1.19
    No
  • C’ GFP library in Starvation Media
    YBR274W
    cytosol
    14.86
    0.94
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    17.6219
    1.1247
    No