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Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YER089C
    nucleus:cytosol
    71.64
  • N' NOP1pr-GFP in SD
    YER089C
    cytosol
    160.538
  • N' TEF2pr-mCherry in SD
    YER089C
    cytosol
    223.391
  • N' NATIVEpr-GFP in SD
    YER089C
    cytosol
    80.1098
  • N' TEF2pr-VC and Cyto-VN in SD
    YER089C
    cytosol
    60.7044
  • C’ GFP library in SD+DTT 
    YER089C
    nucleus.cytosol
    53.23
    0.74
    No
  • C’ GFP library in SD+H2O2
    YER089C
    nucleus.cytosol
    58.08
    0.81
    No
  • C’ GFP library in Starvation Media
    YER089C
    nucleus,cytosol
    28.57
    0.39
    Yes
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    nucleus:cytosol
  • C’ GFP library on the background of CCT mutant
    noimage.png
    nucleus:cytosol
    70.998
    0.99096
    No