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Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YHR079C
    below threshold
    14.35
  • N' NOP1pr-GFP in SD
    YHR079C
    ER
    55.8015
  • N' TEF2pr-mCherry in SD
    YHR079C
    ER
    30.9263
  • N' NATIVEpr-GFP in SD
    YHR079C
    below threshold
    21.4465
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YHR079C
    cytosol
    17
    1.18
    No
  • C’ GFP library in SD+H2O2
    YHR079C
    cytosol
    15.12
    1.05
    No
  • C’ GFP library in Starvation Media
    YHR079C
    cytosol
    16.62
    1.15
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    14.4753
    1.00816
    No