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Replication initiation protein that loads DNA pol epsilon onto pre-replication complexes at origins; checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p; ortholog of human TopBP1
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YJL090C
    nucleus
    18.78
  • N' NOP1pr-GFP in SD
    YJL090C
    nucleus
    32.2295
  • N' TEF2pr-mCherry in SD
    YJL090C
    nucleus
    49.056
  • N' NATIVEpr-GFP in SD
    YJL090C
    punctate
    18.8178
  • N' TEF2pr-VC and Cyto-VN in SD
    YJL090C
    nucleus
    27.2586
  • C’ GFP library in SD+DTT 
    YJL090C
    nucleus
    19.1
    1.01
    No
  • C’ GFP library in SD+H2O2
    YJL090C
    nucleus
    19.22
    1.02
    No
  • C’ GFP library in Starvation Media
    YJL090C
    nucleus
    17
    0.9
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    nucleus
  • C’ GFP library on the background of CCT mutant
    noimage.png
    nucleus
    20.0181
    1.06564
    No