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Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events
Localization:
Intensity:
Fold change:
Significance:
-
C’ GFP library in SD
below threshold14.99 -
N' NOP1pr-GFP in SD
ER71.494 -
N' TEF2pr-mCherry in SD
ER15.6602 -
N' NATIVEpr-GFP in SD
ER27.6842 -
N' TEF2pr-VC and Cyto-VN in SD
#N/A0 -
C’ GFP library in SD+DTT
cytosol15.651.04No -
C’ GFP library in SD+H2O2
cytosol16.281.08No -
C’ GFP library in Starvation Media
cytosol17.951.19No -
C’ GFP library on the background of Pup2-DaMP
below threshold -
C’ GFP library on the background of CCT mutant
below threshold13.47280.898034No