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Subunit of a complex with Rad50p and Xrs2p (MRX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for MRX function; widely conserved
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YMR224C
    nucleus
    17.99
  • N' NOP1pr-GFP in SD
    YMR224C
    cytosol
    66.6866
  • N' TEF2pr-mCherry in SD
    YMR224C
    cytosol
    63.0597
  • N' NATIVEpr-GFP in SD
    YMR224C
    below threshold
    18.5245
  • N' TEF2pr-VC and Cyto-VN in SD
    YMR224C
    cytosol
    30.7921
  • C’ GFP library in SD+DTT 
    YMR224C
    nucleus
    17.65
    0.98
    No
  • C’ GFP library in SD+H2O2
    YMR224C
    nucleus
    21.06
    1.17
    No
  • C’ GFP library in Starvation Media
    YMR224C
    nucleus
    18.34
    1.01
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    nucleus
  • C’ GFP library on the background of CCT mutant
    noimage.png
    nucleus
    18.9296
    1.05156
    No