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Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YOL006C
    cytosol
    18.84
  • N' NOP1pr-GFP in SD
    YOL006C
    punctate,nucleus
    74.4724
  • N' TEF2pr-mCherry in SD
    YOL006C
    nucleus
    74.9966
  • N' NATIVEpr-GFP in SD
    YOL006C
    nucleus,nucleolus
    26.3791
  • N' TEF2pr-VC and Cyto-VN in SD
    YOL006C
    punctate,nucleus
    48.987
  • C’ GFP library in SD+DTT 
    YOL006C
    cytosol
    17.11
    0.9
    No
  • C’ GFP library in SD+H2O2
    YOL006C
    cytosol
    17.45
    0.92
    No
  • C’ GFP library in Starvation Media
    YOL006C
    cytosol
    16.87
    0.89
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    cytosol
  • C’ GFP library on the background of CCT mutant
    noimage.png
    cytosol
    20.2877
    1.07641
    No