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Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YDL013W
    below threshold
    18.17
  • N' NOP1pr-GFP in SD
    YDL013W
    cytosol,nucleus
    23.1353
  • N' TEF2pr-mCherry in SD
    YDL013W
    nucleus
    12.2777
  • N' NATIVEpr-GFP in SD
    YDL013W
    below threshold
    18.7464
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YDL013W
    cytosol
    16.25
    0.89
    No
  • C’ GFP library in SD+H2O2
    YDL013W
    cytosol
    16.67
    0.91
    No
  • C’ GFP library in Starvation Media
    YDL013W
    cytosol
    16.16
    0.88
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    N/A
    N/A
    No
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