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Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers
Localization:
Intensity:
Fold change:
Significance:
-
C’ GFP library in SD
below threshold18.17 -
N' NOP1pr-GFP in SD
cytosol,nucleus23.1353 -
N' TEF2pr-mCherry in SD
nucleus12.2777 -
N' NATIVEpr-GFP in SD
below threshold18.7464 -
N' TEF2pr-VC and Cyto-VN in SD
#N/A0 -
C’ GFP library in SD+DTT
cytosol16.250.89No -
C’ GFP library in SD+H2O2
cytosol16.670.91No -
C’ GFP library in Starvation Media
cytosol16.160.88No -
C’ GFP library on the background of Pup2-DaMP
below threshold -
C’ GFP library on the background of CCT mutant
below thresholdN/AN/ANo
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