BioNumber of the month
Cell biology is constantly being enriched by an influx of quantitative data on a host of critical quantities. In these vignettes that also serve as the basis for a book on “Cell Biology by the Numbers” written by Ron Milo and Rob Phillips we explore how a knowledge of key numbers that characterize the behavior of cells can be used to make useful inferences in molecular cell biology. One of the ways we try to make sense of these numbers is by making back of the envelope calculations (so called Fermi problems) in biology. These estimates aim to connect the complexity of many problems in biology and the kinds of clear-cut deductions often used potently in the physical sciences.
Nov 2012 - How fast do cells move?
Jul 2012 - How big are nuclei?
Apr 2012 - How fast do RNAs and proteins degrade?
Feb 2012 - How large are chloroplasts?
Dec 2011 - What is the pH of a cell?
Oct 2011 - How big is the “average” protein?
Aug 2011 - How big is a human cell?
Jul 2011 - What is the redox potential of a cell?
May 2011 - How big are viruses?
Feb 2011 - How big are genomes?
Dec 2010 - What is the thickness of the cell membrane?
Nov 2010 - How many genes are in a genome?
Feb 2010 - How big is a yeast cell?
Dec 2009 - What is the elemental composition of a cell?
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