Dr. Clifford E. (Chaim Tzvi) Felder

Research Associate in Theoretical Chemistry and Biochemistry

Dept. of Structural Biology, 653 Kimmelman-Bergman Bldg.; Weizmann Institute of Science, Box 26, 76100 Rehovot, Israel

Phone: (972)-8934-3077; Fax: (972)-8934-4159;
E-mail: clifford.felder @ weizmann.ac.il

Also affiliated with the Dept. of Organic Chemistry

In memorial to my beloved father, David ben Yehoshua, who passed away on 24 July 2010 (14 Av 5770).

Received my PhD in Theoretical Biochemistry - Iowa State University, 1981, with Prof. Jon Applequist, working on electrostatic calculations of molecules inside an evacuated spherical cavity surrounded by a continuous dielectric medium.

I currently work with with two dynamic research groups:

Prof. Joel Sussman, Dept. of Structural Biology: Molecular Modelling of Proteins and Drugs

Molecular mechanics and dynamics
Homology modelling, docking of inhibitors to binding sites
Electrostatic Calculations; Receptor Design Homology
Application to AcetylCholinEsterases
Analysis of Protein Backbone Fold and Oligopeptide Sequence Patterns
Prediction of Whether a Given Peptide Sequence is Natively Unfolded

Prof. Abraham Shanzer, Dept. of Organic Chemistry: Molecular Modelling of Small Organic/Organometallic Compounds

Transition Metal Chelators, Sidphores and Biomimetic Analogs
Interactive Computational-Experimental Approach
Development of Empirical Interatomic Force Parameters
Innovate Strategies of Conformational Scanning
Application to Ferrichrome,Ferrioxamine,Desferal and Biomimetic Analogs

I used to work for Prof. Shneior Lifson of the Chemical Physics Department. Prof. Lifson was one of the principal pioneers in developing the molecular force field. He passed away Monday 22 Jan. 2001 (27 Teves 5761)

You are welcome to try out my server that calculates dipole moments of proteins,
and the FoldIndex server to predict if a Protein Sequence may be Natively Unfolded.

Weizmann Institute students and staff are invited to examine my web page about available Molecular Structural/Graphical Databases and Applications. To use this resource, try to click here.

"How great are Thy works, Oh L-rd, with wisdom Thou hast created them all, the world is full of Thy creations." (Psalm 104:24) Through studying the wonders of His Creation, we come to better understand the greatness of the Creator Himself, may He be Blessed.

Here is my list of Selected Publications.
Professional Interests: Links about Theoretical Chemistry.
Personal Interests: Links about Judaism and Israel.
E-mail: clifford.felder @ weizmann.ac.il

Return to Joel Sussman's Group Page (for protein modelling on cholinesterases).
Return to Avraham Shanzer's Group Page (for modelling organometallics).

Return to Weizmann Institute Home Page.