Ribosome Structure and Function,
Prof. Ada E. Yonath Group

 Department of Structural Biology
 

The Martin S. and Helen Kimmel Professor of Structural Biology
Director, The Helen and Milton A. Kimmelman Center for Biomolecular Structure and Assembly

Tel: (972) 8 934 3028/2541;
Fax: (972) 8 934 4154/4136

ada.yonath@weizmann.ac.il

Ribosome Group led by Prof Ada Yonath:
Structural Biology Department, Weizmann Institute of Science, Rehovot, Israel

Members of the group: 
Dr. Agmon Ilana, Dr. Auerbach-Nevo Tamar, Baram David, Dr. Bashan Anat, Dr. Belousoff Matthew, Dr. Caspi Yaron, Davidovich Chen, Grossman Moran, Pyetan Erez, Dr. Kessler Maggie, Laschever Miriam, Mermershtain Inbal, Dr. Peretz Moshe, Dr. Rozenberg Haim, Shapira Tal, Tel-Or Shoshi, Weissman Lior, Wekselman Itai, Dr. Zarivach Raz, Dr. Zimmerman Ella

Scientific Activities and explanation to the below Figures
Publications
Ada E.Yonath Curriculum Vitae

 

Schluenzen et al., Cell, 102, 615-23 (2000)

Figure A:

The Small Ribosomal Subunit

Schluenzen et al., Cell, 102, 615-23 (2000)
Harms et al., Cell, 107, 679-88 (2001)

Figure B:

The Large Ribosomal Subunit

 

Harms et al., Cell, 107, 679-88 (2001)

 

Agmon etal., Eur J Biochem, 270, 2543-56(2003); Bashan et al., Mol Cell, 11,91-102 (2003); Yonath, ChemBioChem 4, 1008-17 (2003); Yonath, Biol Chem 384, 1411-9 (2003)

*Figure C:

tRNA A-site --->P site

 

Agmon et al., 2003; Bashan et al., 2003

*For details go to "Scientific Activities" (Figure 5)
Agmon et al., Eur J Biochem, 270, 2543-56 (2003); Bashan et al., Mol Cell, 11,91-102 (2003)

*Figure D:

tRNA A-site--->P passage

Agmon et al., 2003; 2005

 

 

*For details go to "Scientific Activities" (Figure 5)

 
Figure E:

View into the Tunnel

 

Schluenzen et al., Nature, 413, 814-21 (2001)

 

Schluenzen et al., Nature, 413, 814-21 (2001)
Figure F:

Antibiotic Agents Blocking the Ribosmal Exit Tunnel

 

Schluenzen et al., Nature, 413, 814-21 (2001)

 

Berisio, et al., Nat Struct Biol, 10, 366-70 (2003)
*Figure G:
The motif N-ter(~150aa)
FXXXXWIXXXXGIRAGP-C-ter (X being any amino acid) induces elongation arrest while SecM protein is being formed Nakatogawa & Ito, Cell 108, 629-36, (2002).

Similar motifs were identified in tryptophanase (tnaC) operon Gong & Yanofsky, Science 297, 1864-7, (2002).

Berisio, et al., Nat Struct Biol, (2003)

*For details go to "Scientific Activities" (Figure 10)

 

Scientific Activities and explanation to the below Figures
Publications
Ada E.Yonath Curriculum Vitae


Weizmann Institute of Science, Rehovot, 76100 Israel
Tel: (972) 8 934 3028/2541   Fax: (972) 8 934 4154/4136;
Email: ada.yonath@weizmann.ac.il