Sussman/Silman Group Movies

Acetylcholinesterase (AChE)

Acetylcholinesterase (AChE)

References:

 

How synchrotron radiation can rapidly cause specific damage to a protein

Drug Discoveries

Conformational changes upon ligand binding

Drug Discoveries

Visualizing conformational changes in AChE via morphing (Movies by T. Zeev-Ben-Mordehai, I. Silman & J.L. Sussman)

Cholinesterase Like Adhesion Molecules (CLAMs)

 

References:

Zeev-Ben-Mordehai, T., Silman, I. & Sussman, J.L.
Acetylcholinesterase in motion: Visualizing conformational changes in crystal structures by a morphing procedure.
Biopolymers 68, 395-406 (2003). [Abstract] [PDF]