1. Suss O, Halfin O, Porat Z, Fridmann Sirkis Y, Motiei L, Margulies D (2024). Artificial Protein Crosstalk with a Molecule that Exchanges Binding Partners.  Angew. Chem. Int. Ed. 2024, 63 :e20231246.
  2. Motiei L, Margulies D (2023). Molecules that Generate Fingerprints: A New Class of Fluorescent Sensors for Chemical Biology, Medical Diagnosis, and Cryptography.  Acc. Chem. Res. 2023, 56 :1803–1814.
  3. Winer L, Motiei L, Margulies D (2023). Fluorescent Investigation of Proteins Using DNA-Synthetic Ligand Conjugates.  Bioconjug. Chem. 2023, 34 :1509–1522.
  4. Prasad P K, Eizenshtadt N, Goliand I, Liat Fellus-Alyagor L, Oren R, Golani O, Motiei L, Margulies D (2023). Chemically Programmable Bacterial Probes for the Recognition of Cell Surface Proteins.  Mater. Today Bio. 2023, 20 :100669.
  5. Weinstein J Y, Martí‐Gómez C, Lipsh-Sokolik R, Hoch S Y, Liebermann D, Nevo R, Weissman H, Petrovich-Kopitman E, Margulies D, Ivankov D, McCandlish D M, Fleishman S J (2023). Designed Active-Site Library Reveals Thousands of Functional GFP Variants.  Nat. Commun. 2023, 14 :2890.
  6. Kishore Prasad P, Motiei L, Margulies D (2023). Applications of Bacteria Decorated with Synthetic DNA Constructs.  Small. 2023, 12 : 2206136.
    • Special Issue: Synthetic biology and biomimicry.
  7. Hatai J, Altay Y, Sood A, Kiani A, Eleveld M, Motiei L, Margulies D,* Otto S,* (2022). An Optical Probe for Real-Time Monitoring of Self-Replicator Emergence and Distinguishing between Replicators.  J. Am. Chem. Soc. 2022, 144 :3074−3082.
  8. Levin M, Margulies D (2021). Editorial: Special Issue on “Fluorescent Molecular Probes and Fluorescence-Based Chemical Sensing.  Isr. J. Chem. 2021, 61 :158.
  9. Suss O, Motiei L, Margulies D, (2021). Broad Applications of Thiazole Orange in Fluorescent Sensing of Biomolecules and Ions.  Molecules. 2021, 26 :2828.
    • Special Issue: Recent advances in molecular sensors.
  10. Kishore Prasad P, Motiei L, Margulies D (2021). Steps toward Enhancing the Fluorescence of Small-Molecule-based Protein Labels Using Supramolecular Hosts.  Results in Chemistry. 2021, 3 :100134.
  11. Adler S, Motiei L, Mankovski N, Cohen H, Margulies D (2021). Fluorescent Labelling of Cell Surface Proteins on a Solid Support.  Isr. J. Chem. 2021, 61 :239-243.
    • Special issue: Fluorescent molecular probes and fluorescence‐based chemical sensing
  12. Hatai J, Kishore Prasad P, Lahav-Mankovski L, Oppenheimer-Low N, Unger T, Fridmann Sirkis Y, Dadosh T, Motiei L, Margulies D (2021). Assessing Changes in the Expression Levels of Cell Surface Proteins with a Turn-on Fluorescent Molecular Probe .  Chem. Commun. 2021, 57 :1875-1878 .
  13. Peri-Naor R, Pode Z, Lahav-Mankovski N, Rabinkov A, Motiei L, Margulies D (2020). Glycoform Differentiation by a Targeted, Self-Assembled, Pattern-Generating Protein Surface Sensor.  J. Am. Chem. Soc. 2020, 142 :15790-15798.
  14. Kishore Prasad P, Lahav-Mankovski N, Motiei L, Margulies D (2020). Encrypting Messages with Artificial Bacterial Receptors.  Beilstein J. Org. Chem. 2020, 16 :2749–2756.
    • In memory of Prof. Carsten Schmuck
  15. Lahav-Mankovski N, Kishore Prasad P, Oppenheimer-Low N, Raviv G, Dadosh T, Unger T, Meir Salame T, Motiei L, Margulies D (2020). Decorating Bacteria with Self-Assembled Synthetic Receptors.  Nature Commun. 2020, 11 :1299.
  16. Unger-Angel L, Motiei L, Margulies D (2019). Molecular Logic as a Means to Assess Therapeutic Antidotes.  Front. Chem. 2019, 7 :243.
    • "Rising Stars" article collection
  17. Lustgarten O, Carmieli R, Motiei L, Margulies D (2019). A Molecular Secret Sharing Scheme.  Angew. Chem. Int. Ed. 2019, 58 :184-188.
  18. Pode Z, Peri-Naor R, Georgeson J. M, Ilani T, Kiss V, Unger T, Markus B, Barr H. M, Motiei L, Margulies D (2017). Protein Recognition by a Pattern-Generating Fluorescent Molecular Probe.  Nature Nanotechnol. 2017, 12 :1161–1168.
  19. Lustgarten O, Motiei L, Margulies D (2017). User Authorization at the Molecular Scale.  ChemPhysChem. 2017, 18 :1678-1687.
    • VIP paper
  20. Hatai J, Motiei L, Margulies D (2017). Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor.  J. Am. Chem. Soc. 2017, 139 :2136-2139.
  21. Nissinkorn Y, Motiei L, Margulies D (2016). Protein Surface Recognition with Targeted Fluorescent Molecular Probes.  Receptors Clin. Investig. 2016, 3 : e1381.
    • Invited highlight article
  22. Sarkar T, Selvakumar K, Motiei L, Margulies D (2016). Message in a Molecule.  Nature Commun. 2016, (7) :11374.
  23. Peri-Naor R, Motiei L, Margulies D (2016). Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy.  J. Vis. Exp. 2016, 115 :e54396.
    • Invited paper
  24. Selvakumar K, Motiei L, Margulies D (2015). Enzyme-Artificial Enzyme Interactions as a Means for Discriminating among Structurally Similar Isozymes.  J. Am. Chem. Soc. 2015, 137 :4892-4895.
  25. Guez-Haddad J, Sporny M, Sasson Y, Gevorkyan-Airapetov L, Lahav-Mankovski N, Margulies D Radzimanowski J, Opatowsky Y (2015). The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism .  Structure. 2015, 23 :1989-2000.
  26. Peri-Naor R, Motiei L, Margulies D (2015). Artificial Signal Transduction Therapy: A Futuristic Approach to Disease Treatment.  Future Med. Chem. 2015, 7 :2091-2093.
    • Invited editorial paper (special issue: chemical biology spotlight)
  27. Nissinkorn Y, Lahav-Mankovski N, Rabinkov A, Albeck S, Motiei L, Margulies D (2015). Sensing Protein Surfaces with Targeted Fluorescent Receptors.  Chem. Eur. J. 2015, 21 :15981–15987 .
  28. Unger-Angel L, Rout B, Ilani T, Eisenstein M, Motiei L, Margulies D (2015). Protein Recognition by Bivalent, ‘Turn-On’ Fluorescent Molecular Probes.  Chem. Sci. 2015, 6 :5419-5425.
  29. Peri-Naor R, Ilani T, Motiei L, Margulies D (2015). Protein-Protein Communication and Enzyme Activation Mediated by a Synthetic Chemical Transducer.  J. Am. Chem. Soc. 2015, 137 :9507-9510.
  30. Motiei L, Pode Z, Koganitsky A, Margulies D (2014). Targeted Protein Surface Sensors as a Tool for Analyzing Small Populations of Proteins in Biological Mixtures.  Angew. Chem. Int. Ed. 2014, 53 :9289-9293.
  31. Rout B, Motiei L, Margulies D (2014). Combinatorial Fluorescent Molecular Sensors: The Road to Differential Sensing at the Molecular Level.  Synlett. 2014, 25 :1050-1054.
    • Invited Synpacts prospect article
  32. Rout B, Milko P, Iron MA, Motiei L, Margulies D (2013). D. Authorizing Multiple Chemical Passwords by a Combinatorial Molecular Keypad Lock.  J. Am. Chem. Soc . 2013, 135 :15330–15333.
    • Featured in
    • highlighted in SYNPACTS.
  33. Rout B, Unger L, Armony G, Iron MA, Margulies D (2012). Medication Detection by a Combinatorial Fluorescent Molecular Sensor.  Angew. Chem. Int. Ed. 2012, 51 :12477-12481.
    • Feature on the back cover
    • Highlighted by faculty of 1000
    • Highlighted in SYNPACTS
  34. Margulies D, Hamilton AD (2010). Combinatorial Protein Recognition as an Alternative Approach to Antibody-Mimetics.  Curr. Opin. Chem. Biol. 2010, 14 :705-712.
  35. Margulies D, Hamilton AD (2009). Protein Recognition by an Ensemble of Fluorescent DNA G-Quadruplexes.  Angew. Chem. Int. Ed. 2009, 48 :1771-1774.
    • Selected as a "Hot Paper" by the editors.
    • Highlighted in Nat. Chem. 2009, 1, 20-21.
  36. Margulies D, Hamilton AD (2009). Digital Analysis of Protein Properties by an Ensemble of DNA Quadruplexes.  J. Am. Chem. Soc. 2009, 131 :9142–9143 .
  37. Margulies D, Opatowsky Y, Fletcher S, Saraogi I, Tsou K, Saha S, Schlessinger J, Hamilton AD (2009). Surface Binding Inhibitors of the SCF-KIT Protein- Protein Interaction.  ChemBioChem. 2009, 10 :1955-1958.
  38. Margulies D, Felder CE, Melman G, Shanzer A (2007). A Molecular Keypad Lock: A Photochemical Device Capable of Authorizing Password Entries.  J. Am. Chem. Soc. 2007, 129 :347-354.
    • Selected by the ACS office of communications science writers as one of five first-of-their-kind        discoveries among the 30,000 ACS papers published in 2007
    • Highlighted in Angew. Chem. Int. Ed. 2007, 46, 5472-5475.
    •  Highlighted in RSC Chemistry World News (January 2007)
  39. Margulies D, Melman G, Shanzer A (2006). A Molecular Full-Adder and Full-Subtractor, an Additional Step toward a Moleculator.  J. Am. Chem. Soc. 2006, 128 :4865-4871.
    •  Highlighted in Nature 2006, 440, 719.
  40. Margulies D, Melman G, Shanzer A (2005). Fluorescein as a Model Molecular Calculator with Reset Capability.  Nat. Mater. 2005, 4 :768-771.
    • Among Nature editors' choices of chemistry papers from NPG journals from 2005-2006 at the ACS spring meeting 2006.
  41. Margulies D, Melman G, Felder CE, Arad-Yellin R, Shanzer A (2004). Chemical Input Multiplicity Facilitates Arithmetical Processing.  J. Am.Chem. Soc. 2004, 126 :15400-15401.
    • Highlighted in Nature. Mater. 2005, 4, 15-16.
  42. Ashkenasy G, Margulies D, Felder CE, Shanzer A, Powers LS (2002). Bidentate Ligation of Heme Analogues; Novel Biomimetics of the Peroxidase Active Site.  Chem. Eur. J. 2002, 8 :4017-4026.