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Program
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Program

TUESDAY, September 2, 2008
14:00 - 14:15 Opening ceremony
  Daniel Zajfman, President of the Weizmann Institute of Science
  Yossi Yarden, Symposium Chairman
   
14:00 - 17:30 Session on Systems Biology of Biological Networks
Chairman: Yinon Ben-Neriah
14:15 - 15:00 PLENARY LECTURE: Boris Kholodenko 
Spatio-Temporal coding of signal specificity   
15:00 - 15:30 David Gilbert
Biochemical models-what can we do with them?
15:30 - 16:00  Coffee Break
16:00 - 16:30 Eytan Domany
Chromosomal instabilities and cancer
16:30 - 16:45 Selected Poster: Masha Niv
Computational tools for peptidomimetic inhibitors of protein-protein interactions
16:45 - 17:30 PLENARY LECTURE: Ravi Iyengar
Spatial regulation of signaling network topology
   
WEDNESDAY, September 3, 2008
09:00 - 12:35 Session on Biochemical Analysis of Complex Signaling Pathways
Chairman: Gideon Rechavi
09:00 - 09:45 PLENARY LECTURE: Michael Yaffe
A systems biology approach to apoptotic control and DNA damage signaling
09:45 - 10:15 Kun-Liang Guan 
TSC-mTOR pathway in cell growth
10:15 - 10:45 Piero Crespo
Dimers and scaffolds as spatial regulators of ERK signals
10:45 - 11:05  Coffee Break
11:05 - 11:35 Rony Seger
Nuclear shuttling of ERKs and MEKs: Novel mechanism on the way to oncogenic transformation
11:35 - 11:50 Selected Poster: David Engelberg
Production of constitutively active p38s and ERKs, and revealing their mechanism of action
11:50 - 12:35 PLENARY LECTURE: Richard Marais
RAS and RAF signalling in melanoma
12:35 - 14:30 Lunch  Break  & Poster Presentation
14:30 - 17:45 Session on Clinical Applications of Signaling Networks
Chairman: Ron Pinter
14:30 - 15:15 PLENARY LECTURE: Gordon Mills
A systems approach to drug development and implementation
15:15 - 15:45 Marco Pierotti
Targeted therapy: Lesson from GIST and chordoma tumors
15:45 - 16:05   Coffee Break
16:05 - 16:35 Josep Tabernero
Molecular biology factors determinant of antitumor activity with targeted therapies in colorectal cancer
16:35 - 16:50 Selected Poster: Noam Shomron
MicroRNAs as oncofetal gene regulators
16:50 - 17:05 Varda Rotter
Identification of specific gene signatures along the process of cell transformation in vitro: relevance to p53
17:05 - 17:50 PLENARY LECTURE: Stephen Friend   
The emerging translational oncology toolkit
17:50 – 18:00 CONCLUDING REMARKS