Host-pathogen immunometabolic crosstalk

We study how metabolic signals shape interactions between hosts and bacterial pathogens. Our work has shown that immune-derived metabolites, which normally support host defense, can be hijacked by pathogens to promote their survival inside host cells—a phenomenon we term immunometabolic crosstalk.

Our lab now focuses on developing advanced in vivo and single-cell approaches to uncover how bacteria adapt their metabolism within infected tissues and how their intracellular niches are organized in space.