Prof. Amnon Horovitz

Prof. Amnon Horovitz

Chemical and Structural Biology
Field
Protein folding and allostery
Research Focus
Structure-function analysis of protein folding chaperone machines

The focus of our research activities is to understand the molecular basis of allosteric transitions in protein machines and how they relate to their function. Much of our work is centered on the GroEL and CCT/TRiC folding machines in E. coli and yeast, respectively. We are interested in understanding their substrate specificity, folding mechanisms and allosteric properties. 

Field
Protein folding and allostery
Research Focus
Structure-function analysis of protein folding chaperone machines