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AnalogYeast
One stop shop for finding analogs for your favorite yeast protein

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YBR022W POA1 / SGDID:S000000226
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YBR022W POA1 SGDID:S000000226
POLN
Polyprotein P1234 (P1234) (Non-structural polyprotein) [Cleaved into: Polyprotein P123' (P123'); Polyprotein P123 (P123); mRNA-capping enzyme nsP1 (EC 2.1.1.-) (EC 2.7.7.-) (Non-structural protein 1); Protease nsP2 (EC 3.1.3.33) (EC 3.4.22.-) (EC 3.6.1.15) (EC 3.6.4.13) (Non-structural protein 2) (nsP2); Non-structural protein 3' (nsP3') (EC 3.1.3.84); Non-structural protein 3 (nsP3) (EC 3.1.3.84); RNA-directed RNA polymerase nsP4 (EC 2.7.7.19) (EC 2.7.7.48) (Non-structural protein 4) (nsP4)]
2.7.7.19,2.7.7.48,3.1.3.33,3.1.3.84,3.6.1.15,3.6.4.13, Venezuelan equine
3gqe_b P36328 99.60 1.10E-19 6.80E-24 119.40 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
3C-like proteinase (EC 3.4.19.12) (EC 3.4.22.69) (Growth factor-like peptide) (Leader protein) (Non-structural protein 10) (Non-structural protein 2) (Non-structural protein 3) (Non-structural protein 4) (Non-structural protein 6) (Non-structural protein 7) (Non-structural protein 8) (Non-structural protein 9) (Papain-like proteinase) (nsp5) (p65 homolog)
3C-like proteinase (EC 3.4.19.12) (EC 3.4.22.69) (Growth factor-like peptide) (Leader protein) (Non-structural protein 10) (Non-structural protein 2) (Non-structural protein 3) (Non-structural protein 4) (Non-structural protein 6) (Non-structural protein 7) (Non-structural protein 8) (Non-structural protein 9) (Papain-like proteinase) (nsp5) (p65 homolog)
3.4.19.12,3.4.22.69, Middle East
5zua_a T2B9G2 99.70 2.20E-22 1.40E-26 132.40 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
OARD1 C6orf130 TARG1
ADP-ribose glycohydrolase OARD1 (O-acetyl-ADP-ribose deacetylase 1) (EC 3.5.1.-) (Terminal ADP-ribose protein glycohydrolase 1) ([Protein ADP-ribosylglutamate] hydrolase OARD1) (EC 3.2.2.-)
3.2.2.-,3.5.1.-, Homo sapiens
Familial Hypercholesterolemia,Hypercholesterolemia, Familial, 4,Arthrogryposis, Renal Dysfunction, And Cholestasis 1
4j5q_a Q9Y530 ENSG00000124596 OARD1 99.60 1.40E-20 8.90E-25 120.80 1 1 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
SCO6735
SCO6735
Streptomyces coelicolor
5e3b_a Q9X7P1 99.70 2.70E-22 1.80E-26 133.50 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
MACROH2A2 H2AFY2
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Homo sapiens
Anus Benign Neoplasm,Plantar Wart
2xd7_b Q9P0M6 ENSG00000099284 MACROH2A2 99.70 5.90E-21 3.80E-25 128.10 1 1 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
GDAP2
Ganglioside-induced differentiation-associated protein 2
Homo sapiens
Spinocerebellar Ataxia, Autosomal Recessive 27,Hereditary Ataxia,Kabuki Syndrome 1
4uml_a Q9NXN4 ENSG00000196505 GDAP2 99.70 2.80E-22 1.80E-26 138.10 1 1 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
MACROD1 LRP16
ADP-ribose glycohydrolase MACROD1 (MACRO domain-containing protein 1) (O-acetyl-ADP-ribose deacetylase MACROD1) (EC 3.1.1.106) (Protein LRP16) ([Protein ADP-ribosylaspartate] hydrolase MACROD1) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD1) (EC 3.2.2.-)
3.1.1.106 Homo sapiens
Endometrial Cancer,Cardiomyopathy, Dilated, 1e,Hereditary Spastic Paraplegia,Familial Hypercholesterolemia,Hypercholesterolemia, Familial, 4
2x47_a Q9BQ69 ENSG00000133315 MACROD1 99.70 3.30E-22 2.10E-26 138.30 1 1 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
rep 1a-1b
Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.-) (PL1-PRO/PL2-PRO) (PLP1/PLP2) (Papain-like proteinases 1/2) (p195); Non-structural protein 4 (nsp4) (Peptide HD2); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10); Non-structural protein 11 (nsp11); RNA-directed RNA polymerase (Pol) (RdRp) (EC 2.7.7.48) (nsp12); Helicase (Hel) (EC 3.6.4.12) (EC 3.6.4.13) (nsp13); Exoribonuclease (ExoN) (EC 3.1.13.-) (nsp14); Uridylate-specific endoribonuclease (EC 3.1.-.-) (NendoU) (nsp15); Putative 2'-O-methyl transferase (EC 2.1.1.-) (nsp16)]
2.7.7.48,3.4.19.12, Feline coronavirus
3eti_e Q98VG9 99.70 7.70E-23 4.90E-27 134.60 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
POLN
Polyprotein P1234 (P1234) (Non-structural polyprotein) [Cleaved into: Polyprotein P123 (P123); mRNA-capping enzyme nsP1 (EC 2.1.1.-) (EC 2.7.7.-) (Non-structural protein 1); Protease nsP2 (EC 3.1.3.33) (EC 3.4.22.-) (EC 3.6.1.15) (EC 3.6.4.13) (Non-structural protein 2) (nsP2); Non-structural protein 3 (nsP3) (EC 3.1.3.84); RNA-directed RNA polymerase nsP4 (EC 2.7.7.19) (EC 2.7.7.48) (Non-structural protein 4) (nsP4)]
2.7.7.19,2.7.7.48,3.1.3.33,3.1.3.84,3.6.1.15 Chikungunya virus
3gpg_b Q8JUX6 99.60 2.50E-20 1.60E-24 122.50 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
OB2288
OB2288
Oceanobacillus iheyensis
5lbp_a Q8EP31 99.60 2.30E-19 1.50E-23 121.70 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
BT_1257
BT_1257
Bacteroides thetaiotaomicron
2fg1_a Q8A8B0 99.70 6.90E-23 4.50E-27 133.40 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
Tc00.1047053509179.20
Tc00.1047053509179.20
Trypanosoma cruzi
5fsz_a Q4DQ03 99.60 1.30E-20 8.60E-25 132.10 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
PARP14 BAL2 KIAA1268
Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2) (Poly [ADP-ribose] polymerase 14) (PARP-14)
2.4.2.- Homo sapiens
3q6z_a Q460N5 ENSG00000173193 PARP14 99.60 8.50E-21 5.50E-25 129.40 0 1 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
YMR087W YM9582.12
Probable ADP-ribose 1''-phosphate phosphatase YML087W (EC 3.1.3.84)
3.1.3.84 Saccharomyces cerevisiae
1txz_a Q04299 99.60 3.30E-20 2.10E-24 131.10 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
Macroh2a1 H2afy
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y)
Rattus norvegicus
1yd9_a Q02874 99.60 1.90E-19 1.20E-23 120.50 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
SA0314
Protein-ADP-ribose hydrolase (EC 3.2.1.-)
3.2.1.- Staphylococcus aureus
5kiv_a P67344 99.70 8.80E-22 5.70E-26 138.50 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
ymdB b1045 JW1032
O-acetyl-ADP-ribose deacetylase (EC 3.1.1.106) (Regulator of RNase III activity)
3.1.1.106 Escherichia coli
1spv_a P0A8D6 99.90 3.20E-28 2.10E-32 161.00 0 0 0 0 0 0 0 1
YBR022W POA1 SGDID:S000000226
rep 1a-1b
Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 2 (nsp2) (p87); Non-structural protein 3 (nsp3) (EC 3.4.22.-) (Papain-like proteinase) (PL-PRO) (p195); Non-structural protein 4 (nsp4) (Peptide HD2) (p41); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5) (p33); Non-structural protein 6 (nsp6) (p34); Non-structural protein 7 (nsp7) (p9); Non-structural protein 8 (nsp8) (p24); Non-structural protein 9 (nsp9) (p10); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL) (p16); RNA-directed RNA polymerase (Pol) (RdRp) (EC 2.7.7.48) (nsp12) (p100); Helicase (Hel) (EC 3.6.4.12) (EC 3.6.4.13) (nsp13) (p68); Exoribonuclease (ExoN) (EC 3.1.13.-) (nsp14) (p58); Uridylate-specific endoribonuclease (EC 3.1.-.-) (NendoU) (nsp15) (p39); Putative 2'-O-methyl transferase (EC 2.1.1.-) (nsp16) (p35)]
2.7.7.48,3.6.4.13, Avian infectious
3ejf_a P0C6Y1 99.60 4.60E-20 2.90E-24 122.00 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
rep 1a-1b
Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Host translation inhibitor nsp1 (Leader protein) (Non-structural protein 1) (nsp1); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (Main protease) (Mpro) (Non-structural protein 5) (nsp5) (SARS coronavirus main proteinase); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); RNA-directed RNA polymerase (Pol) (RdRp) (EC 2.7.7.48) (Non-structural protein 12) (nsp12); Helicase (Hel) (EC 3.6.4.12) (EC 3.6.4.13) (Non-structural protein 13) (nsp13); Proofreading exoribonuclease (ExoN) (EC 2.1.1.-) (EC 3.1.13.-) (Guanine-N7 methyltransferase) (Non-structural protein 14) (nsp14); Uridylate-specific endoribonuclease (EC 3.1.-.-) (NendoU) (Non-structural protein 15) (nsp15); 2'-O-methyltransferase (EC 2.1.1.-) (Non-structural protein 16) (nsp16)]
2.7.7.48,3.4.19.12,3.4.22.69,3.6.4.13, Severe acute
2acf_d P0C6X7 99.70 2.70E-21 1.80E-25 128.70 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
rep 1a-1b
Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (p9); Non-structural protein 2 (nsp2) (p87); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.-) (PL1-PRO/PL2-PRO) (PLP1/PLP2) (Papain-like proteinases 1/2) (p195); Non-structural protein 4 (nsp4) (Peptide HD2); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5) (p34); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7) (p5); Non-structural protein 8 (nsp8) (p23); Non-structural protein 9 (nsp9) (p12); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL) (p16); RNA-directed RNA polymerase (Pol) (RdRp) (EC 2.7.7.48) (nsp12) (p100); Helicase (Hel) (EC 3.6.4.12) (EC 3.6.4.13) (nsp13) (p66) (p66-HEL); Exoribonuclease (ExoN) (EC 3.1.13.-) (nsp14); Uridylate-specific endoribonuclease (EC 3.1.-.-) (NendoU) (nsp15) (p41); Putative 2'-O-methyl transferase (EC 2.1.1.-) (nsp16)]
2.7.7.48,3.4.19.12,3.6.4.13 Human coronavirus
3ejg_a P0C6X1 99.70 2.80E-21 1.80E-25 129.70 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
1a
Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 2 (nsp2) (p87); Non-structural protein 3 (nsp3) (EC 3.4.22.-) (Papain-like proteinase) (PL-PRO) (p195); Non-structural protein 4 (nsp4) (Peptide HD2) (p41); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5) (p33); Non-structural protein 6 (nsp6) (p34); Non-structural protein 7 (nsp7) (p9); Non-structural protein 8 (nsp8) (p24); Non-structural protein 9 (nsp9) (p10); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL) (p16); Non-structural protein 11 (nsp11)]
3.4.22.- Avian infectious
3ewo_a P0C6V5 99.60 2.80E-20 1.80E-24 123.20 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
1a
Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (p9); Non-structural protein 2 (nsp2) (p87); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.-) (PL1-PRO/PL2-PRO) (PLP1/PLP2) (Papain-like proteinases 1/2) (p195); Non-structural protein 4 (nsp4) (Peptide HD2); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5) (p34); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7) (p5); Non-structural protein 8 (nsp8) (p23); Non-structural protein 9 (nsp9) (p12); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL) (p14); Non-structural protein 11 (nsp11)]
3.4.19.12 Human coronavirus
2vri_a P0C6U6 99.60 1.80E-20 1.20E-24 123.80 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
1a
Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (p9); Non-structural protein 2 (nsp2) (p87); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.-) (PL1-PRO/PL2-PRO) (PLP1/PLP2) (Papain-like proteinases 1/2) (p195); Non-structural protein 4 (nsp4) (Peptide HD2); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5) (p34); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7) (p5); Non-structural protein 8 (nsp8) (p23); Non-structural protein 9 (nsp9) (p12); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL) (p16); Non-structural protein 11 (nsp11)]
3.4.19.12 Human coronavirus
3ewq_a P0C6U2 99.70 2.50E-21 1.60E-25 127.30 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
ymdB b1045 JW1032
O-acetyl-ADP-ribose deacetylase (EC 3.1.1.106) (Regulator of RNase III activity)
3.1.1.106 Escherichia coli
5cb3_a P0A8D6 99.60 1.60E-20 1.10E-24 124.80 0 0 0 0 0 0 0 1
YBR022W POA1 SGDID:S000000226
MACROH2A1 H2AFY
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Homo sapiens
Breast Cancer,Fanconi Anemia, Complementation Group A,Liebenberg Syndrome,Medulloblastoma
5iit_a O75367 ENSG00000113648 MACROH2A1 99.60 3.60E-20 2.30E-24 136.00 1 1 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
Rv0060
Rv0060
Mycobacterium tuberculosis
5m3i_d O53605 99.70 1.90E-21 1.30E-25 127.40 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
AF_1521
ADP-ribose glycohydrolase AF_1521 ([Protein ADP-ribosylaspartate] hydrolase AF_1521) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase AF_1521) (EC 3.2.2.-)
3.2.2.- Archaeoglobus fulgidus
2bfq_a O28751 99.60 5.80E-20 3.70E-24 123.10 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
1a
Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Host translation inhibitor nsp1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Papain-like proteinase (PL-PRO) (EC 3.4.19.12) (EC 3.4.22.69) (Non-structural protein 3) (nsp3); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]
3.4.19.12,3.4.22.69, Middle East
5dus_a K9N638 99.70 2.60E-22 1.70E-26 132.10 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
TbgDal_V3640
TbgDal_V3640
Trypanosoma brucei
5fsv_a C9ZP98 99.70 2.80E-22 1.80E-26 140.30 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
TaqDRAFT_4250
TaqDRAFT_4250
Thermus aquaticus
5m31_a B7A854 99.70 4.70E-21 3.00E-25 125.60 0 0 0 0 0 0 0 0
YBR022W POA1 SGDID:S000000226
MACROD2 C20orf133
ADP-ribose glycohydrolase MACROD2 (MACRO domain-containing protein 2) (O-acetyl-ADP-ribose deacetylase MACROD2) (EC 3.5.1.-) ([Protein ADP-ribosylaspartate] hydrolase MACROD2) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD2) (EC 3.2.2.-)
3.2.2.-,3.5.1.-, Homo sapiens
Hypogonadotropic Hypogonadism 21 With Or Without Anosmia,Familial Hypercholesterolemia,Disease Of Mental Health,Hypercholesterolemia, Familial, 4,Kallmann Syndrome,Schizophrenia,Autism Spectrum Disorder,Kabuki Syndrome 1,Autism
4iqy_a A1Z1Q3 ENSG00000172264 MACROD2 99.70 3.40E-22 2.20E-26 138.50 1 1 0 0 0 0 0 0

Weizmann Institute of Science | Maya Schuldiner Lab