| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YBR030W | RKM3 | SGDID:S000000234 | KMT2A ALL1 CXXC7 HRX HTRX MLL MLL1 TRX1 |
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.354) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] |
2.1.1.354 | Homo sapiens | Childhood Acute Lymphocytic Leukemia,Lymphoblastic Lymphoma,Hypertrichosis,Chronic Neutrophilic Leukemia,Chronic Myelomonocytic Leukemia,Cornelia De Lange Syndrome,Leukemia, Chronic Myeloid,Acute Myeloid Leukemia With T(9;11)(P22;Q23),B-Lymphoblastic Leukemia/Lymphoma,B-Lymphoblastic Leukemia/Lymphoma With Bcr-Abl1,B-Lymphoblastic Leukemia/Lymphoma With Iamp21,Rare Genetic Intellectual Disability,Myeloproliferative Neoplasm,Leukemia,Pancytopenia,Mixed Phenotype Acute Leukemia,Childhood Leukemia,Acute Leukemia,Leukemia, Acute Myeloid,Acute Myeloid Leukemia With 11q23 Abnormalities,Intravascular Large B-Cell Lymphoma,Familial Isolated Trichomegaly,Myelodysplastic/Myeloproliferative Neoplasm,Hematologic Cancer,Leukemia, Acute Lymphoblastic,Ring Chromosome 21,Acute Megakaryoblastic Leukemia Without Down Syndrome,Rubinstein Taybi Like Syndrome,Central Nervous System Leukemia,Monocytic Leukemia,Ring Chromosome,Myeloid Sarcoma,Myeloid Leukemia,Acute Megakaryocytic Leukemia,Acute Monoblastic Leukemia,Colon Leiomyoma,Cytogenetically Normal Acute Myeloid Leukemia,Microcephaly,Hypoxia,Chronic Granulomatous Disease,Alacrima, Achalasia, And Mental Retardation Syndrome,Leukemia, Acute Lymphoblastic 3,Disease Of Mental Health,Cornelia De Lange Syndrome 1,Lymphoma, Non-Hodgkin, Familial,Wiedemann-Steiner Syndrome,Myelodysplastic Syndrome,Hairy Elbows,Acute Promyelocytic Leukemia,Wilms Tumor 1,Kabuki Syndrome 1,Kbg Syndrome,Leukemia, Acute Monocytic,Leukemia, Chronic Lymphocytic,Juvenile Myelomonocytic Leukemia,Autosomal Dominant Non-Syndromic Intellectual Disability,Autism |
5f5e_a | Q03164 | ENSG00000118058 | KMT2A | 96.70 | 3.80E-06 | 3.60E-10 | 72.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBR030W | RKM3 | SGDID:S000000234 | BN1205_038210 TGVEG_216080 |
BN1205_038210 TGVEG_216080 |
Toxoplasma gondii | 6fnd_b | B9Q0K5 | 99.30 | 2.00E-16 | 2.00E-20 | 159.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YBR030W | RKM3 | SGDID:S000000234 | SMYD2 KMT3C |
N-lysine methyltransferase SMYD2 (EC 2.1.1.-) (HSKM-B) (Histone methyltransferase SMYD2) (EC 2.1.1.354) (Lysine N-methyltransferase 3C) (SET and MYND domain-containing protein 2) |
2.1.1.354 | Homo sapiens | 4wuy_a | Q9NRG4 | ENSG00000143499 | SMYD2 | 99.20 | 2.60E-15 | 2.50E-19 | 154.20 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YBR030W | RKM3 | SGDID:S000000234 | SETD6 |
N-lysine methyltransferase SETD6 (EC 2.1.1.-) (SET domain-containing protein 6) |
2.1.1.- | Homo sapiens | Familial Colorectal Cancer Type X,Meningioma, Familial |
3qxy_a | Q8TBK2 | ENSG00000103037 | SETD6 | 99.90 | 2.50E-33 | 2.30E-37 | 297.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBR030W | RKM3 | SGDID:S000000234 | RBCMT |
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic (EC 2.1.1.127) ([Fructose-bisphosphate aldolase]-lysine N-methyltransferase) (EC 2.1.1.259) ([Ribulose-bisphosphate carboxylase]-lysine N-methyltransferase) (PsLSMT) (RuBisCO LSMT) (RuBisCO methyltransferase) (rbcMT) |
2.1.1.127,2.1.1.259, | Pisum sativum | 2h21_b | Q43088 | 99.90 | 3.60E-33 | 3.30E-37 | 296.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBR030W | RKM3 | SGDID:S000000234 | Smyd1 Bop |
Histone-lysine N-methyltransferase Smyd1 (EC 2.1.1.354) (CD8b-opposite) (SET and MYND domain-containing protein 1) (Zinc finger protein BOP) (m-BOP) |
2.1.1.354 | Mus musculus | 3n71_a | P97443 | 99.00 | 5.30E-14 | 5.30E-18 | 144.70 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YBR030W | RKM3 | SGDID:S000000234 | set7 SPCC297.04c |
SET domain-containing protein 7 (EC 2.1.1.-) |
2.1.1.- | Schizosaccharomyces pombe | 5h6z_a | Q9Y7Q6 | 97.60 | 4.70E-08 | 4.40E-12 | 86.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBR030W | RKM3 | SGDID:S000000234 | SMYD3 ZMYND1 ZNFN3A1 |
Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) |
2.1.1.354 | Homo sapiens | Cerebellar Ataxia, Nonprogressive, With Mental Retardation,Renal Wilms' Tumor,Hepatocellular Carcinoma |
5v37_a | Q9H7B4 | ENSG00000185420 | SMYD3 | 99.10 | 1.70E-14 | 1.60E-18 | 145.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBR030W | RKM3 | SGDID:S000000234 | SETD3 C14orf154 |
Actin-histidine N-methyltransferase (EC 2.1.1.85) (SET domain-containing protein 3) (hSETD3) |
2.1.1.85 | Homo sapiens | Meier-Gorlin Syndrome 1 |
6icv_b | Q86TU7 | ENSG00000183576 | SETD3 | 100.00 | 2.20E-34 | 2.00E-38 | 310.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |