| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YBR280C | SAF1 | SGDID:S000000484 | RCC1 CHC1 |
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) |
Homo sapiens | Retinitis Pigmentosa,Nephronophthisis,Fundus Dystrophy,Retinitis Pigmentosa 3,Raynaud Disease,Joubert Syndrome 1 |
1a12_a | P18754 | 99.70 | 7.80E-22 | 7.10E-26 | 207.90 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YBR280C | SAF1 | SGDID:S000000484 | HERC2 |
E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) |
2.3.2.26 | Homo sapiens | Angelman Syndrome,Optic Nerve Hypoplasia, Bilateral,Wolfram Syndrome 1,Breast Cancer,Wolfram Syndrome,Skin/Hair/Eye Pigmentation, Variation In, 1,Fanconi Anemia, Complementation Group A,Mental Retardation, Autosomal Recessive 38,Prader-Willi Syndrome,Dermatosis Papulosa Nigra,Autosomal Dominant Nonsyndromic Deafness,Wolfram-Like Syndrome, Autosomal Dominant,Albinism, Oculocutaneous, Type Ii,Bardet-Biedl Syndrome 1 |
3kci_a | O95714 | ENSG00000128731 | HERC2 | 99.00 | 8.30E-14 | 7.90E-18 | 141.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBR280C | SAF1 | SGDID:S000000484 | RCC1 CHC1 |
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) |
Homo sapiens | Retinitis Pigmentosa,Nephronophthisis,Fundus Dystrophy,Retinitis Pigmentosa 3,Raynaud Disease,Joubert Syndrome 1 |
1a12_b | P18754 | ENSG00000180198 | RCC1 | 99.10 | 5.50E-15 | 5.20E-19 | 152.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YBR280C | SAF1 | SGDID:S000000484 | SRM1 MTR1 PRP20 YGL097W |
Guanine nucleotide exchange factor SRM1 (Pheromone response pathway component SRM1) (Pre-mRNA-processing protein 20) (Regulator of chromosome condensation) (Suppressor of receptor mutations 1) (mRNA transport protein 1) |
Saccharomyces cerevisiae | 3of7_a | P21827 | 99.10 | 1.40E-14 | 1.30E-18 | 153.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YBR280C | SAF1 | SGDID:S000000484 | Rcc1 Bj1 CG10480 |
Regulator of chromosome condensation (Chromatin-binding protein Bj1) (Regulator of chromosome condensation 1 ortholog) |
Drosophila melanogaster | 3mvd_l | P25171 | 99.10 | 5.20E-15 | 4.90E-19 | 153.60 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | ||||
| YBR280C | SAF1 | SGDID:S000000484 | ATS1 KTI13 YAL020C FUN28 YAL006 |
Protein KTI13 (Alpha-tubulin suppressor 1) (Kluyveromyces lactis toxin-insensitive protein 13) |
Saccharomyces cerevisiae | 4d4q_a | P31386 | 98.60 | 8.00E-12 | 7.40E-16 | 125.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YBR280C | SAF1 | SGDID:S000000484 | HERC1 |
Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) |
2.3.2.26 | Homo sapiens | Autoimmune Lymphoproliferative Syndrome, Type Iii,Syndromic Intellectual Disability,Macrocephaly, Dysmorphic Facies, And Psychomotor Retardation |
4o2w_b | Q15751 | ENSG00000103657 | HERC1 | 98.90 | 3.50E-13 | 3.30E-17 | 138.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YBR280C | SAF1 | SGDID:S000000484 | RPGR RP3 XLRP3 |
X-linked retinitis pigmentosa GTPase regulator |
Homo sapiens | Retinitis Pigmentosa 75,Senior-Loken Syndrome 1,Retinitis Pigmentosa,Retinitis Pigmentosa 7,Enhanced S-Cone Syndrome,Cone-Rod Dystrophy 13,Scotoma,Bardet-Biedl Syndrome,Myopia,Primary Ciliary Dyskinesia,Pathologic Nystagmus,Eye Degenerative Disease,Joubert Syndrome 3,Ciliary Dyskinesia, Primary, 4,Usher Syndrome Type 2,Retinal Ciliopathy,Nephronophthisis,Leber Plus Disease,Retinitis Pigmentosa 19,Retinal Degeneration,Cone-Rod Dystrophy 6,Night Blindness,Fundus Dystrophy,Color Blindness,Nephronophthisis 2,Eye Disease,Optic Disk Drusen,Retinal Disease,Red-Green Color Blindness,Achromatopsia,Usher Syndrome, Type I,Choroid Disease,Stargardt Disease,Retinitis Pigmentosa 25,Macular Degeneration, Age-Related, 1,Retinitis Pigmentosa 31,Retinitis Pigmentosa 3,Cone-Rod Dystrophy, X-Linked, 2,Cone-Rod Dystrophy 2,Immunodeficiency 25,Retinitis Pigmentosa 24,Retinitis Pigmentosa 35,Retinitis,Retinitis Pigmentosa 4,Retinitis Pigmentosa 20,Retinitis Pigmentosa 40,Retinitis Pigmentosa 23,Retinitis Pigmentosa 10,Retinitis Pigmentosa 39,Retinitis Pigmentosa, X-Linked, And Sinorespiratory Infections, With Or Without Deafness,Cone-Rod Dystrophy, X-Linked, 3,Retinitis Pigmentosa 34,Kartagener Syndrome,Sensory System Disease,Usher Syndrome,Macular Degeneration, X-Linked Atrophic,Congenital Stationary Night Blindness,Exudative Vitreoretinopathy,Visceral Heterotaxy,Late-Onset Retinal Degeneration,Cranioectodermal Dysplasia,Leber Congenital Amaurosis 10,Asphyxiating Thoracic Dystrophy,Nephronophthisis 19,Retinitis Pigmentosa 28,Fundus Albipunctatus,Vitelliform Macular Dystrophy,Ciliary Dyskinesia, Primary, 1,Ciliary Dyskinesia, Primary, 8,Cone Dystrophy,Choroideremia,Cone-Rod Dystrophy, X-Linked, 1,Meckel Syndrome, Type 1,Developmental And Epileptic Encephalopathy 1,Leber Hereditary Optic Neuropathy, Modifier Of,Alstrom Syndrome,Leber Congenital Amaurosis 2,Muscular Dystrophy, Duchenne Type,Ornithine Transcarbamylase Deficiency, Hyperammonemia Due To,Macular Dystrophy, Dominant Cystoid,Retinitis Pigmentosa 2,Retinitis Pigmentosa 6,Retinoschisis 1, X-Linked, Juvenile,Bietti Crystalline Corneoretinal Dystrophy,Retinitis Pigmentosa 13,Retinitis Pigmentosa 14,Gyrate Atrophy Of Choroid And Retina,Joubert Syndrome 1,Retinitis Pigmentosa 17 |
4jhp_c | Q92834 | ENSG00000156313 | RPGR | 99.00 | 5.80E-14 | 5.40E-18 | 144.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YBR280C | SAF1 | SGDID:S000000484 | RCC1L WBSCR16 |
RCC1-like G exchanging factor-like protein (RCC1-like) (Williams-Beuren syndrome chromosomal region 16 protein) |
Homo sapiens | Senior-Loken Syndrome 1,Retinitis Pigmentosa,Nephronophthisis,Fundus Dystrophy,Optic Disk Drusen,Retinitis Pigmentosa 3,Retinitis Pigmentosa 34,Williams-Beuren Syndrome,Albinism, Oculocutaneous, Type Ii |
5xgs_b | Q96I51 | ENSG00000274523 | RCC1L | 99.10 | 9.50E-15 | 9.00E-19 | 151.80 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YBR280C | SAF1 | SGDID:S000000484 | UVR8 At5g63860 MGI19.7 |
Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8) |
Arabidopsis thaliana | 4dnu_a | Q9FN03 | 98.70 | 2.00E-12 | 2.00E-16 | 129.10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | ||||
| YBR280C | SAF1 | SGDID:S000000484 | RCC2 KIAA1470 TD60 |
Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa) |
Homo sapiens | Spermatogenic Failure 5,Renal Cell Carcinoma, Nonpapillary |
5gwn_a | Q9P258 | ENSG00000179051 | RCC2 | 99.10 | 1.50E-14 | 1.40E-18 | 152.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |