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AnalogYeast
One stop shop for finding analogs for your favorite yeast protein

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YDL058W USO1 / SGDID:S000002216
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YDL058W USO1 SGDID:S000002216
KPNA5
Importin subunit alpha-6 (Karyopherin subunit alpha-5)
Homo sapiens
Ebola Hemorrhagic Fever,Influenza,Bicipital Tenosynovitis
4u2x_f O15131 ENSG00000196911 KPNA5 97.00 8.90E-07 1.10E-10 83.80 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
TOR2 DRR2 TSC14 YKL203C
Serine/threonine-protein kinase TOR2 (EC 2.7.1.67) (EC 2.7.11.1) (Dominant rapamycin resistance protein 2) (Phosphatidylinositol 4-kinase TOR2) (PI4-kinase TOR2) (PI4K TOR2) (PtdIns-4-kinase TOR2) (Target of rapamycin kinase 2) (Temperature-sensitive CSG2 suppressor protein 14)
2.7.1.67,2.7.11.1, Saccharomyces cerevisiae
6emk_c P32600 95.20 0.00025 2.90E-08 96.20 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
AP1B1 ADTB1 BAM22 CLAPB2
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Homo sapiens
Ichthyosis,Mental Retardation, Enteropathy, Deafness, Peripheral Neuropathy, Ichthyosis, And Keratoderma,Keratitis-Ichthyosis-Deafness Syndrome, Autosomal Recessive,Meningioma, Familial,Keratitis-Ichthyosis-Deafness Syndrome, Autosomal Dominant
6cri_i Q10567 ENSG00000100280 AP1B1 96.70 2.50E-06 3.10E-10 94.50 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
sys-1 CELE_T23D8.9 T23D8.9
sys-1 CELE_T23D8.9 T23D8.9
Caenorhabditis elegans
3c2g_a Q9XVI2 96.50 9.50E-06 7.90E-10 99.00 0 0 0 0 0 1 0 0
YDL058W USO1 SGDID:S000002216
Myosin 2 heavy chain striated muscle
Myosin 2 heavy chain striated muscle
Aphonopelma
3jbh_g A0A140UGH3 98.60 7.50E-12 8.10E-16 170.70 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
MYH7 MYHCB
Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
Homo sapiens
Ventricular Septal Defect,Muscular Disease,Heart Disease,Lymphopenia,Congenital Fiber-Type Disproportion,Mitral Valve Insufficiency,Severe Combined Immunodeficiency,Aortic Valve Disease 2,Congenital Structural Myopathy,Myopathy,Cardiomyopathy, Dilated, 1e,Myofibrillar Myopathy,Atrial Heart Septal Defect,Mitochondrial Dna Depletion Syndrome 12b,Muscle Tissue Disease,Neuromuscular Disease,Myopathy, Myosin Storage, Autosomal Dominant,Bethlem Myopathy 1,Hypertrophic Cardiomyopathy,Myosinopathies,Familial Isolated Dilated Cardiomyopathy,Rasopathy,Autosomal Dominant Distal Myopathy,Myocardial Infarction,Myopathy, Distal, 1,Muscular Dystrophy,Progressive Familial Heart Block,Tibial Muscular Dystrophy,Hyaline Body Myopathy,Atrial Standstill 1,Combined Immunodeficiency,Dilated Cardiomyopathy,Oculopharyngeal Muscular Dystrophy,Combined T And B Cell Immunodeficiency,Long Qt Syndrome,Malignant Hyperthermia,Heart Conduction Disease,Muscular Dystrophy, Congenital, Lmna-Related,Ebstein Anomaly,Cardiac Conduction Defect,Cardiomyopathy, Familial Hypertrophic, 4,Congestive Heart Failure,Endocardial Fibroelastosis,Rigid Spine Muscular Dystrophy 1,Camptocormism,Noonan Syndrome With Multiple Lentigines,Respiratory Failure,Mobitz Type Ii Atrioventricular Block,Myopathy, Myofibrillar, 9, With Early Respiratory Failure,Long Qt Syndrome 2,Danon Disease,Congenital Myasthenic Syndrome,Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With Or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy,Scapuloperoneal Myopathy, Myh7-Related,Restrictive Cardiomyopathy,Arrhythmogenic Right Ventricular Cardiomyopathy,Brugada Syndrome,Stormorken Syndrome,Immune Deficiency Disease,Familial Atrial Fibrillation,Atrioventricular Block,First-Degree Atrioventricular Block,Tricuspid Valve Disease,Barth Syndrome,Holt-Oram Syndrome,Long Qt Syndrome 1,Cardiomyopathy, Familial Hypertrophic, 1,Wolff-Parkinson-White Syndrome,Intrinsic Cardiomyopathy,Peripartum Cardiomyopathy,Lipoprotein Quantitative Trait Locus,Atrial Fibrillation,Scapuloperoneal Myopathy,Cardiac Arrest,Left Ventricular Noncompaction,Myopathy, Myosin Storage, Autosomal Recessive,Catecholaminergic Polymorphic Ventricular Tachycardia,Batten-Turner Congenital Myopathy,Myopathy, Congenital, With Fiber-Type Disproportion,Miyoshi Muscular Dystrophy,Craniosynostosis 4,Cardiomyopathy, Dilated, 1b
5tby_a P12883 ENSG00000092054 MYH7 98.80 4.50E-13 4.80E-17 182.60 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Kpna2 Rch1
Importin subunit alpha-1 (Importin alpha P1) (Karyopherin subunit alpha-2) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (RAG cohort protein 1) (SRP1-alpha)
Mus musculus
1ial_a P52293 99.00 5.20E-14 6.30E-18 156.30 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
TNPO1 KPNB2 MIP1 TRN
Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP)
Homo sapiens
Retinitis Pigmentosa,Meningoencephalitis,Amyotrophic Lateral Sclerosis 20,Retinitis Pigmentosa 2
1qbk_b Q92973 ENSG00000083312 TNPO1 96.60 4.00E-06 5.00E-10 98.50 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
unc-45 CELE_F30H5.1 F30H5.1
unc-45 CELE_F30H5.1 F30H5.1
Caenorhabditis elegans
4i2w_a G5EG62 98.70 2.00E-12 1.90E-16 167.00 0 0 0 0 0 1 0 0
YDL058W USO1 SGDID:S000002216
PPP2R1A
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Homo sapiens
Uterine Body Mixed Cancer,Uterine Carcinosarcoma,Lung Cancer Susceptibility 3,Carcinosarcoma,Suppression Of Tumorigenicity 12,Uterine Corpus Cancer,Clear Cell Adenofibroma,Female Reproductive Endometrioid Cancer,Breast Cancer,Squamous Cell Carcinoma, Head And Neck,Colorectal Cancer,Ovarian Serous Cystadenocarcinoma,Endometrial Serous Adenocarcinoma,Cystadenocarcinoma,Serous Cystadenocarcinoma,Endometrioid Ovary Carcinoma,Microcephaly,Breast Disease,Mixed Cell Type Cancer,Gastric Adenocarcinoma,Brachydactyly,Mental Retardation, Autosomal Dominant 36,Ovarian Clear Cell Carcinoma,Uterine Corpus Endometrial Carcinoma,Autism Spectrum Disorder,Lung Cancer
1b3u_b P30153 96.90 1.50E-06 1.90E-10 96.20 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
SRP1 KAP60 YNL189W N1606
Importin subunit alpha (Karyopherin subunit alpha) (Karyopherin-60) (Serine-rich RNA polymerase I suppressor protein)
Saccharomyces cerevisiae
1ee4_b Q02821 99.00 7.20E-14 9.00E-18 151.40 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Copb1 Copb
Coatomer subunit beta (Beta-coat protein) (Beta-COP)
Mus musculus
5a1y_o Q9JIF7 95.00 0.00037 4.00E-08 86.50 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
CLASP2 KIAA0627
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2)
Homo sapiens
Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome
5nr4_a O75122 ENSG00000163539 CLASP2 95.50 0.00013 1.60E-08 70.50 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
HGH1 YGR187C G7538
Protein HGH1 (HMG1/2 protein homolog)
Saccharomyces cerevisiae
6hb1_d P48362 98.30 2.20E-10 2.30E-14 130.20 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
IPO4 IMP4B RANBP4
Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)
Homo sapiens
Anemia, Congenital Dyserythropoietic, Type Ia
5xah_a Q8TEX9 ENSG00000196497 IPO4 95.60 0.0001 1.30E-08 78.10 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
CTHT_0033460
CTHT_0033460
Chaetomium thermophilum
4gmo_a G0S5S6 97.10 5.80E-07 5.60E-11 111.20 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Ap1g1 Adtg Clapg1
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma-adaptin) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Mus musculus
6cri_r P22892 96.90 1.10E-06 1.30E-10 99.80 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Kpnb1 Impnb
Importin subunit beta-1 (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG)
Mus musculus
1ukl_b P70168 96.20 1.70E-05 2.10E-09 93.00 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
DOHH HLRC1
Deoxyhypusine hydroxylase (hDOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase) (HEAT-like repeat-containing protein 1)
1.14.99.29 Homo sapiens
Familial Expansile Osteolysis
4d4z_a Q9BU89 95.20 0.00021 2.50E-08 72.20 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
CTNND1 KIAA0384
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Homo sapiens
Esophagus Carcinoma In Situ,Melanoma,Cleft Lip,Cleft Lip With Or Without Cleft Palate,Ectodermal Dysplasia,Colon Adenocarcinoma,Euryblepharon,Lobular Neoplasia,Breast Cancer,Colorectal Cancer,Pulmonary Sclerosing Hemangioma,Blepharocheilodontic Syndrome 2,Blepharocheilodontic Syndrome 1,Gastric Cancer,Prostate Cancer,Cri-Du-Chat Syndrome,Ectropion,Distichiasis,Tooth Agenesis,Gastric Cancer, Hereditary Diffuse,Lung Cancer,Pancreatic Cancer
3l6x_a O60716 ENSG00000198561 CTNND1 98.90 1.10E-13 1.20E-17 165.20 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
USO1 VDP
General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein)
Bos taurus
3grl_a P41541 100.00 3.10E-54 3.30E-58 536.80 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
KLLA0_E20769g
KLLA0_E20769g
Kluyveromyces lactis
5vch_b Q6CMF0 95.30 0.00018 2.20E-08 87.10 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Bicdl1 Bicdr1 Ccdc64
BICD family-like cargo adapter 1 (Bicaudal D-related protein 1) (BICD-related protein 1) (BICDR-1) (Coiled-coil domain-containing protein 64A)
Mus musculus
6f1t_x A0JNT9 95.10 0.00035 3.20E-08 80.60 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Ap2a2 Adtab
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Mus musculus
2jkt_l P17427 96.70 3.00E-06 3.50E-10 97.40 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)
Homo sapiens
Schwartz-Jampel Syndrome, Type 1
5xgc_a P52306 ENSG00000138698 RAP1GDS1 99.00 5.10E-14 6.30E-18 156.40 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
PKP2
Plakophilin-2
Homo sapiens
Arrhythmogenic Right Ventricular Dysplasia, Familial, 2,Heart Disease,Cardiomyopathy, Dilated, 1e,Naxos Disease,Hypertrophic Cardiomyopathy,Familial Isolated Arrhythmogenic Right Ventricular Dysplasia,Arrhythmogenic Right Ventricular Dysplasia, Familial, 1,Familial Woolly Hair Syndrome,Atrial Standstill 1,Dilated Cardiomyopathy,Right Bundle Branch Block,Long Qt Syndrome,Arrhythmogenic Right Ventricular Dysplasia, Familial, 9,Left Bundle Branch Hemiblock,Heart Conduction Disease,Cardiac Sarcoidosis,Arrhythmogenic Right Ventricular Dysplasia, Familial, 3,Arrhythmogenic Right Ventricular Dysplasia, Familial, 4,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Right Dominant Form,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Biventricular Form,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Left Dominant Form,Cardiac Arrhythmia,Palmoplantar Keratosis,Arrhythmogenic Right Ventricular Dysplasia, Familial, 10,Arrhythmogenic Right Ventricular Dysplasia, Familial, 13,Long Qt Syndrome 2,Left Ventricular Noncompaction 1,Arrhythmogenic Right Ventricular Dysplasia, Familial, 11,Arrhythmogenic Right Ventricular Dysplasia, Familial, 5,Arrhythmogenic Right Ventricular Dysplasia, Familial, 6,Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With Or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy,Restrictive Cardiomyopathy,Arrhythmogenic Right Ventricular Cardiomyopathy,Brugada Syndrome,Arrhythmogenic Right Ventricular Dysplasia, Familial, 12,Cardiomyopathy, Dilated, With Woolly Hair And Keratoderma,Familial Atrial Fibrillation,Long Qt Syndrome 1,Intrinsic Cardiomyopathy,Lipoprotein Quantitative Trait Locus,Arrhythmogenic Right Ventricular Dysplasia, Familial, 8,Left Ventricular Noncompaction,Anomalous Left Coronary Artery From The Pulmonary Artery,Catecholaminergic Polymorphic Ventricular Tachycardia,Palmoplantar Keratoderma, Nonepidermolytic
3tt9_a Q99959 ENSG00000057294 PKP2 97.80 8.80E-09 1.00E-12 103.70 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
hmp-2 K05C4.6
Beta-catenin-like protein hmp-2 (Protein humpback-2)
Caenorhabditis elegans
4r10_a O44326 99.00 8.00E-14 9.70E-18 159.70 0 0 0 0 0 1 0 0
YDL058W USO1 SGDID:S000002216
CTNNB1 CTNNB OK/SW-cl.35 PRO2286
Catenin beta-1 (Beta-catenin)
Homo sapiens
Adult Hepatocellular Carcinoma,Pancreatic Adenocarcinoma,Mesothelioma, Malignant,Skin Melanoma,Bone Remodeling Disease,Heart Disease,Bone Resorption Disease,Uterine Body Mixed Cancer,Uterine Carcinosarcoma,Endometrial Cancer,Bile Duct Disease,Squamous Cell Carcinoma,Pfeiffer Syndrome,Retinitis Pigmentosa,Thyroid Gland Cancer,Hair Disease,Lung Cancer Susceptibility 3,Adenoid Cystic Carcinoma,Carcinosarcoma,Spasticity,Liver Benign Neoplasm,Cowden Syndrome,Polycystic Kidney Disease,Suppression Of Tumorigenicity 12,Melanoma,Endometrial Hyperplasia,Desmoid Tumor,Thyroid Gland Anaplastic Carcinoma,Diabetes Mellitus,Mullerian Aplasia And Hyperandrogenism,Adenoma,Parathyroid Carcinoma,Diffuse Idiopathic Skeletal Hyperostosis,Clubfoot,Cerebral Palsy,Rectum Adenocarcinoma,Peripheral Nervous System Neoplasm,Uterine Corpus Cancer,Bone Sarcoma,Pancreatoblastoma,Clear Cell Renal Cell Carcinoma,Alzheimer Disease,Hepatoblastoma,Rasopathy,Myocardial Infarction,Pleomorphic Adenoma,Mucoepidermoid Carcinoma,Intravascular Fasciitis,Atypical Teratoid Rhabdoid Tumor,Bile Duct Cancer,Intestinal Benign Neoplasm,Malignant Ovarian Surface Epithelial-Stromal Neoplasm,Ovary Epithelial Cancer,Mammary Analogue Secretory Carcinoma,Amelogenesis Imperfecta,Retinal Cancer,Pseudosarcomatous Fibromatosis,Biliary Tract Disease,Embryonal Sarcoma,Infratentorial Cancer,Isolated Anorectal Malformation,Endocervical Carcinoma,Classic Pulmonary Blastoma,Cataract 30,Alopecia,Parathyroid Adenoma,Polymorphous Low-Grade Adenocarcinoma,Colon Adenocarcinoma,Neuroblastoma,Colonic Benign Neoplasm,Vulvar Intraepithelial Neoplasia,Fibromatosis,Bile Duct Adenocarcinoma,Small Intestine Adenocarcinoma,Intrahepatic Cholangiocarcinoma,Tubular Adenocarcinoma,Sclerosing Hemangioma,Leukemia, Acute Myeloid,Nephronophthisis,Bone Marrow Cancer,Basal Cell Carcinoma,Leber Plus Disease,Hemangioma,Atypical Polypoid Adenomyoma,Hemimegalencephaly,Fibrolamellar Carcinoma,Cataract,Vitreoretinopathy,Neurodevelopmental Disorder With Spastic Diplegia And Visual Defects,Liver Cirrhosis,Chondroma,Adenomyoma,Autonomic Nervous System Neoplasm,Carney Complex Variant,Dilated Cardiomyopathy,Basal Cell Nevus Syndrome,Ureteral Obstruction,Aortic Valve Disease 1,Bladder Cancer,Liver Adenomatosis,Simpson-Golabi-Behmel Syndrome,Focal Segmental Glomerulosclerosis,Small Intestine Cancer,Brain Cancer,Colonic Disease,Hair Follicle Neoplasm,Microcystic Stromal Tumor,Vaginal Adenoma,Endometrial Adenocarcinoma,Intrahepatic Bile Duct Adenoma,Oropharynx Cancer,Cervix Carcinoma,Ulcerative Colitis,Osteoporosis,Ovarian Cancer,Adenocarcinoma,In Situ Carcinoma,T-Cell Acute Lymphoblastic Leukemia,Female Reproductive Endometrioid Cancer,Breast Ductal Carcinoma,Lobular Neoplasia,Acinar Cell Carcinoma,Breast Carcinoma In Situ,Breast Cancer,Squamous Cell Carcinoma, Head And Neck,Actinic Keratosis,Microphthalmia,Malignant Astrocytoma,High Grade Glioma,Exudative Vitreoretinopathy 7,Colorectal Cancer,Peripheral Nervous System Disease,Pulmonary Sclerosing Hemangioma,Gallbladder Cancer,Hepatocellular Carcinoma,Endometrioid Ovary Carcinoma,Keratoacanthoma,Microcephaly,Frozen Shoulder,Rhabdomyosarcoma,Tongue Disease,Spastic Diplegia,Ovarian Disease,Polycystic Kidney Disease 1 With Or Without Polycystic Liver Disease,Teratoma,Bipolar Disorder,Alacrima, Achalasia, And Mental Retardation Syndrome,Gonadal Dysgenesis,Peutz-Jeghers Syndrome,Sarcoma,Cleft Palate, Isolated,Liposarcoma,Spondyloarthropathy,Hyaline Fibromatosis Syndrome,Skin Carcinoma,Gastric Cancer,Lymphangioma,Cone-Rod Dystrophy 2,Prostate Cancer,Disease Of Mental Health,Signet Ring Cell Adenocarcinoma,Pancreatic Ductal Adenocarcinoma,Brittle Bone Disorder,Cholangiocarcinoma,Conventional Fibrosarcoma,Pseudomyxoma Peritonei,Testicular Gonadoblastoma,Cervical Cancer,Ovarian Cystadenocarcinoma,Mixed Cell Type Cancer,Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1a,Central Nervous System Cancer,Pulmonary Fibrosis, Idiopathic,Congenital Myasthenic Syndrome,Adrenal Cortical Carcinoma,Retinal Detachment,Ovary Adenocarcinoma,Gastric Adenocarcinoma,Type 2 Diabetes Mellitus,Plasmacytoma,Cervical Squamous Cell Carcinoma,Craniopharyngioma,Adamantinous Craniopharyngioma,Papillary Craniopharyngioma,Childhood Medulloblastoma,Nodular Medulloblastoma,Lynch Syndrome,Lung Squamous Cell Carcinoma,Adrenal Carcinoma,Adrenal Cortex Disease,Thyroid Gland Follicular Carcinoma,Schizophrenia,Merkel Cell Carcinoma,Albinism, Ocular, With Late-Onset Sensorineural Deafness,Bladder Urothelial Carcinoma,Holzgreve Syndrome,Renal Cell Carcinoma, Papillary, 1,Beckwith-Wiedemann Syndrome,Malaria,Familial Adenomatous Polyposis,Arrhythmogenic Right Ventricular Cardiomyopathy,Sarcoma, Synovial,Neural Tube Defects,Pilomatrixoma,Van Buchem Disease,Exudative Vitreoretinopathy,Esophageal Cancer,Odontochondrodysplasia,Orofacial Cleft,Exudative Vitreoretinopathy 1,Strabismus,Birt-Hogg-Dube Syndrome,Desmoid Disease, Hereditary,Tooth Agenesis,Respiratory System Benign Neoplasm,Reproductive Organ Benign Neoplasm,Gastrointestinal System Benign Neoplasm,Barrett Esophagus,Gastric Cancer, Hereditary Diffuse,Alveolar Soft Part Sarcoma,Autosomal Genetic Disease,Mantle Cell Lymphoma,Renal Hypodysplasia/Aplasia 1,Androgenic Alopecia,Renal Fibrosis,Colorectal Adenoma,Colorectal Adenocarcinoma,Tongue Squamous Cell Carcinoma,Oral Squamous Cell Carcinoma,Hepatocellular Adenoma,Fibroma,Townes-Brocks Syndrome,Syndromic Intellectual Disability,Adrenal Cortical Adenoma,Gallbladder Adenoma,Ameloblastoma,Bone Squamous Cell Carcinoma,Brain Stem Medulloblastoma,Colon Adenoma,Large Intestine Adenocarcinoma,Nasopharyngeal Carcinoma,Wilms Tumor 1,Wolf-Hirschhorn Syndrome,Hypertension, Essential,Lipoprotein Quantitative Trait Locus,Pre-Malignant Neoplasm,Estrogen-Receptor Negative Breast Cancer,Cell Type Benign Neoplasm,Endocrine Organ Benign Neoplasm,Central Nervous System Benign Neoplasm,Cardiovascular Organ Benign Neoplasm,Uterine Benign Neoplasm,Osteoblastoma,Vaginal Benign Neoplasm,Connective Tissue Benign Neoplasm,Colitis,Wilson-Turner X-Linked Mental Retardation Syndrome,Sclerosteosis,Gallbladder Disease,Primary Pigmented Nodular Adrenocortical Disease,Amelogenesis Imperfecta, Type Ig,Li-Fraumeni Syndrome,Norrie Disease,Anus, Imperforate,Myeloma, Multiple,Medulloblastoma,Autism,Melanoma, Cutaneous Malignant 1,Melanoma, Uveal,Autosomal Dominant Non-Syndromic Intellectual Disability 19,Lung Cancer,Adenomyosis,Osteoporosis-Pseudoglioma Syndrome,Pancreatic Cancer
3sl9_b P35222 ENSG00000168036 CTNNB1 97.20 2.60E-07 3.10E-11 86.80 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
PKP1
Plakophilin-1 (Band 6 protein) (B6P)
Homo sapiens
Pemphigus,Naxos Disease,Ectodermal Dysplasia,Epidermolysis Bullosa Simplex,Tooth Ankylosis,Familial Woolly Hair Syndrome,Epidermolysis Bullosa,Bullous Skin Disease,Squamous Cell Carcinoma, Head And Neck,Palmoplantar Keratosis,Ectodermal Dysplasia/Skin Fragility Syndrome,Epidermolysis Bullosa Simplex, Dowling-Meara Type,Epidermolysis Bullosa Simplex With Mottled Pigmentation,Cardiomyopathy, Dilated, With Woolly Hair And Keratoderma,Palmoplantar Keratoderma, Epidermolytic,Palmoplantar Keratoderma, Nonepidermolytic
1xm9_a Q13835 ENSG00000081277 PKP1 98.90 2.70E-13 3.20E-17 151.10 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
PFAG_00718
PFAG_00718
Plasmodium falciparum
5ewp_b W7FPA1 97.70 1.70E-08 1.90E-12 104.20 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
SKLU-Cont10078
SKLU-Cont10078
Lachancea kluyveri
6mze_e A0A493R6X7 96.00 3.90E-05 4.80E-09 84.50 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
JUP CTNNG DP3
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Homo sapiens
Heart Disease,Endometrial Cancer,Pemphigus,Naxos Disease,Hypertrophic Cardiomyopathy,Familial Woolly Hair Syndrome,Grover'S Disease,Atrial Standstill 1,Dilated Cardiomyopathy,Bladder Cancer,Conjunctival Degeneration,Arrhythmogenic Right Ventricular Dysplasia, Familial, 9,Arrhythmogenic Right Ventricular Dysplasia, Familial, 4,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Right Dominant Form,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Biventricular Form,Familial Isolated Arrhythmogenic Ventricular Dysplasia, Left Dominant Form,Colorectal Cancer,Diffuse Palmoplantar Keratoderma,Pemphigus Vulgaris, Familial,Cardiac Arrhythmia,Keratoderma With Woolly Hair,Pinguecula,Epidermolysis Bullosa, Lethal Acantholytic,Palmoplantar Keratosis,Gastric Cancer,Arrhythmogenic Right Ventricular Dysplasia, Familial, 10,Left Ventricular Noncompaction 1,Arrhythmogenic Right Ventricular Dysplasia, Familial, 11,Arrhythmogenic Right Ventricular Dysplasia, Familial, 5,Arrhythmogenic Right Ventricular Dysplasia, Familial, 6,Ectodermal Dysplasia/Skin Fragility Syndrome,Arrhythmogenic Right Ventricular Cardiomyopathy,Brugada Syndrome,Arrhythmogenic Right Ventricular Dysplasia, Familial, 12,Palmoplantar Keratoderma And Woolly Hair,Cardiomyopathy, Dilated, With Woolly Hair And Keratoderma,Wolff-Parkinson-White Syndrome,Arrhythmogenic Right Ventricular Dysplasia, Familial, 8,Left Ventricular Noncompaction,Lung Cancer,Palmoplantar Keratoderma, Nonepidermolytic
3ifq_a P14923 99.00 6.10E-14 7.60E-18 158.20 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
KPNA1 RCH2
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Homo sapiens
Retinitis Pigmentosa,Venezuelan Equine Encephalitis
2jdq_a P52294 ENSG00000114030 KPNA1 98.90 2.00E-13 2.40E-17 150.10 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
RAPTOR1 RAPTOR1B At3g08850 T16O11.22
Regulatory-associated protein of TOR 1 (Protein RAPTOR 1) (Protein RAPTOR 1B) (AtRaptor1b)
Arabidopsis thaliana
5wbj_a Q93YQ1 96.80 3.10E-06 3.00E-10 111.30 0 0 0 0 0 0 1 0
YDL058W USO1 SGDID:S000002216
KPNA4 QIP1
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Homo sapiens
Chikungunya
5xzx_a O00629 ENSG00000186432 KPNA4 98.90 1.30E-13 1.60E-17 149.00 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
PSE1 KAP121 YMR308C YM9952.10C
Importin subunit beta-3 (Karyopherin subunit beta-3) (Karyopherin-121) (Protein secretion enhancer 1)
Saccharomyces cerevisiae
3w3u_a P32337 96.00 3.50E-05 4.40E-09 92.80 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
KAP95 YLR347C L8300.15
Importin subunit beta-1 (Importin-95) (Karyopherin subunit beta-1) (Karyopherin-95)
Saccharomyces cerevisiae
3nd2_a Q06142 96.20 1.90E-05 2.30E-09 92.00 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
HSPBP1 HSPBP PP1845
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Homo sapiens
Sjogren-Larsson Syndrome,Parkinson Disease, Late-Onset,Spinocerebellar Ataxia, Autosomal Recessive 16
1xqr_a Q9NZL4 ENSG00000133265 HSPBP1 97.60 3.80E-08 4.30E-12 105.50 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
yibA b3594 JW3568
Protein YibA
Escherichia coli
1oyz_a P0ADK6 95.30 0.00019 2.30E-08 72.00 0 0 0 0 0 0 0 1
YDL058W USO1 SGDID:S000002216
SHE4 YOR035C OR26.26
SWI5-dependent HO expression protein 4
Saccharomyces cerevisiae
3opb_a P51534 98.50 1.40E-11 1.50E-15 153.00 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
CTNNBL1 C20orf33 PP8304
Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)
Homo sapiens
Niemann-Pick Disease, Type C1
4mfu_a Q8WYA6 ENSG00000132792 CTNNBL1 98.30 2.50E-10 2.50E-14 136.70 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
CTHT_0034860
CTHT_0034860
Chaetomium thermophilum
5mu7_a G0S6G7 96.40 9.50E-06 1.20E-09 85.40 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
APC DP2.5
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Homo sapiens
Adult Hepatocellular Carcinoma,Endocrine Gland Cancer,Endometrial Cancer,Duodenal Benign Neoplasm,Pseudohypoparathyroidism,Lung Cancer Susceptibility 3,Urinary System Disease,Cowden Syndrome,Desmoid Tumor,Adenoma,Parathyroid Carcinoma,Rectum Cancer,B-Lymphoblastic Leukemia/Lymphoma With Hyperdiploidy,B-Lymphoblastic Leukemia/Lymphoma With Hypodiploidy,Myh-Associated Polyposis,Hepatoblastoma,Bile Duct Cancer,Intestinal Benign Neoplasm,Malignant Ovarian Surface Epithelial-Stromal Neoplasm,Ovary Epithelial Cancer,Ocular Cancer,Myeloid Leukemia Associated With Down Syndrome,Retinal Cancer,Infratentorial Cancer,Cervix Disease,Lymphatic System Disease,Female Reproductive System Disease,Small Intestine Benign Neoplasm,Familial Colorectal Cancer,Supratentorial Primitive Neuroectodermal Tumor,Male Reproductive System Disease,Colon Adenocarcinoma,Colonic Benign Neoplasm,Pilocytic Astrocytoma,Gastrointestinal System Disease,Fibromatosis,Serrated Polyposis Syndrome,Bile Duct Adenocarcinoma,Inherited Cancer-Predisposing Syndrome,Intrahepatic Cholangiocarcinoma,Apc-Associated Polyposis Conditions,Hematologic Cancer,Leukemia, Acute Lymphoblastic,B-Lymphoblastic Leukemia/Lymphoma With T,Liver Cirrhosis,Thoracic Cancer,Ampulla Of Vater Benign Neoplasm,Intestinal Disease,Brain Cancer,Endocrine System Disease,Colonic Disease,Oropharynx Cancer,Cervix Carcinoma,Gastric Adenocarcinoma And Proximal Polyposis Of The Stomach,Immune System Disease,Nervous System Disease,Anal Squamous Cell Carcinoma,Familial Adenomatous Polyposis Due To 5q22.2 Microdeletion,Ovarian Cancer,Adenocarcinoma,Eye Disease,Breast Cancer,Large Intestine Cancer,Colorectal Cancer,Nervous System Cancer,Gastrointestinal System Cancer,Hepatocellular Carcinoma,Fourth Cranial Nerve Palsy,Attenuated Familial Adenomatous Polyposis,Deficiency Anemia,Mccune-Albright Syndrome,Juvenile Polyposis Syndrome,Familial Adenomatous Polyposis 1,Peutz-Jeghers Syndrome,Gastric Cancer,Lymphangioma,Reproductive System Disease,Prostate Cancer,Disease Of Mental Health,Cholangiocarcinoma,Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1a,Central Nervous System Cancer,Respiratory System Disease,Gastric Adenocarcinoma,Cranial Nerve Palsy,Craniopharyngioma,Male Reproductive Organ Cancer,Lynch Syndrome,Sensory System Disease,Lymphoma, Non-Hodgkin, Familial,Familial Adenomatous Polyposis,Esophageal Cancer,Inflammatory Bowel Disease,Desmoid Disease, Hereditary,Gastrointestinal System Benign Neoplasm,Barrett Esophagus,Alveolar Soft Part Sarcoma,Tumor Predisposition Syndrome,Autosomal Genetic Disease,Colorectal Cancer, Hereditary Nonpolyposis, Type 5,Uterine Anomalies,Gastrointestinal Stromal Tumor,Periampullary Adenoma,Colorectal Adenoma,Colorectal Adenocarcinoma,Villous Adenoma,Cutaneous Telangiectasia And Cancer Syndrome, Familial,Colon Adenoma,Duodenum Adenoma,Autism Spectrum Disorder,Lymphatic System Cancer,Cell Type Benign Neoplasm,Cardiovascular Organ Benign Neoplasm,Leukemia, Chronic Lymphocytic,Medulloblastoma,Lung Cancer,Cenani-Lenz Syndactyly Syndrome,Pancreatic Cancer
5iz8_a P25054 ENSG00000134982 APC 98.60 4.50E-12 5.20E-16 138.10 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Ctnnb1 Catnb
Catenin beta-1 (Beta-catenin)
Mus musculus
3bct_a Q02248 99.20 2.80E-15 3.50E-19 165.70 0 0 1 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
3H10.030 GE21DRAFT_7666
3H10.030 GE21DRAFT_7666
Neurospora crassa
4rxh_b Q9C2K9 98.80 3.70E-13 4.50E-17 151.90 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
USO1 VDP
General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein)
Homo sapiens
Achondrogenesis,Streptococcal Meningitis,Cone-Rod Dystrophy 2,Hermansky-Pudlak Syndrome
2w3c_a O60763 ENSG00000138768 USO1 100.00 8.90E-45 9.50E-49 443.30 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
VMA13 CLS11 YPR036W YP3085.02
V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 54 kDa subunit) (Vacuolar proton pump subunit H)
Saccharomyces cerevisiae
1ho8_a P41807 98.30 2.30E-10 2.30E-14 136.50 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Os01g0253300 LOC_Os01g14950
Importin subunit alpha-1a
Oryza sativa
4b8j_a Q71VM4 98.80 3.60E-13 4.30E-17 153.70 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
CTHT_0012280
CTHT_0012280
Chaetomium thermophilum
4xri_a G0S143 95.40 0.00015 1.80E-08 84.30 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Ap2a2 Adtab
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Rattus norvegicus
2vgl_a P18484 96.70 3.10E-06 3.70E-10 97.50 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
AP2B1 ADTB2 CLAPB1
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Homo sapiens
Cerebellar Degeneration,Branchiooculofacial Syndrome,Char Syndrome,Rhabdomyosarcoma,Mental Retardation, Autosomal Dominant 56,Patent Ductus Arteriosus 1,Ataxia-Telangiectasia,Hypocalciuric Hypercalcemia, Familial, Type Iii
2vgl_b P63010 ENSG00000006125 AP2B1 97.00 7.20E-07 8.80E-11 100.40 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
MYH7
Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
Bos taurus
6fsa_b Q9BE39 99.00 7.20E-14 7.70E-18 190.60 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
KPNA6 IPOA7
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Homo sapiens
4uad_a O60684 ENSG00000025800 KPNA6 98.80 3.40E-13 4.20E-17 149.80 0 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
VAC8 YEB3 YEL013W
Vacuolar protein 8
Saccharomyces cerevisiae
5xjg_c P39968 99.00 3.10E-14 3.90E-18 158.70 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
KPNB1 NTF97
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Homo sapiens
Retinitis Pigmentosa,Venezuelan Equine Encephalitis,Influenza,Campomelic Dysplasia
1qgr_a Q14974 ENSG00000108424 KPNB1 96.50 6.10E-06 7.50E-10 97.20 1 1 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
SKLU-Cont10078
SKLU-Cont10078
Lachancea kluyveri
6mzg_e A0A493R6X8 95.90 4.30E-05 5.20E-09 85.10 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
YEF3 EFC1 TEF3 YEF3A YLR249W L9672.5
Elongation factor 3A (EF-3) (EF-3A) (EC 3.6.4.-) (Eukaryotic elongation factor 3) (eEF3) (Translation elongation factor 3A) (Yeast elongation factor 3)
3.6.4.- Saccharomyces cerevisiae
2iw3_a P16521 95.70 8.00E-05 9.10E-09 91.60 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
Ap1b1 Adtb1
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Rattus norvegicus
1w63_j P52303 96.90 1.40E-06 1.80E-10 97.20 0 0 0 0 0 0 0 0
YDL058W USO1 SGDID:S000002216
unc-45 Tom34 CG2708
unc-45 Tom34 CG2708
Drosophila melanogaster
3now_a Q960B1 98.80 5.30E-13 6.50E-17 159.20 0 0 0 0 1 0 0 0

Weizmann Institute of Science | Maya Schuldiner Lab