Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YDL182W | LYS20 | SGDID:S000002341 | HMGCL |
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) |
4.1.3.4 | Homo sapiens | Retinitis Pigmentosa,Hypoglycemia,Uniparental Disomy Of Chromosome 1,Reye Syndrome,Methylmalonic Acidemia,Propionic Acidemia,Autosomal Recessive Disease,Metabolic Acidosis,3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency,Fumarase Deficiency,Maple Syrup Urine Disease,Organic Acidemia,Alpha-Methylacetoacetic Aciduria,Left Ventricular Noncompaction |
2cw6_c | P35914 | ENSG00000117305 | HMGCL | 100.00 | 2.50E-36 | 1.80E-40 | 281.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDL182W | LYS20 | SGDID:S000002341 | 5S |
Methylmalonyl-CoA carboxyltransferase 5S subunit (EC 2.1.3.1) (Transcarboxylase 5S subunit) |
2.1.3.1 | Propionibacterium freudenreichii | 1rqb_a | Q70AC7 | 100.00 | 1.60E-44 | 1.10E-48 | 360.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | lys20 TT_C1550 |
Homocitrate synthase (HCS) (EC 2.3.3.14) |
2.3.3.14 | Thermus thermophilus | 2ztj_a | O87198 | 100.00 | 2.70E-61 | 1.90E-65 | 465.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | pyc RHE_CH04002 |
pyc RHE_CH04002 |
6.4.1.1 | Rhizobium etli | 2qf7_b | Q2K340 | 100.00 | 4.60E-38 | 3.20E-42 | 341.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | Tcur_0536 |
Tcur_0536 |
4.1.3.39,4.1.3.43, | Thermomonospora curvata | 4lrs_a | D1A3K8 | 100.00 | 1.70E-40 | 1.20E-44 | 316.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | leuA NMB1070 |
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase) |
2.3.3.13 | Neisseria meningitidis | 3rmj_b | Q9JZG1 | 100.00 | 1.00E-59 | 7.10E-64 | 453.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | leuA Rv3710 MTV025.058 |
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase) |
2.3.3.13 | Mycobacterium tuberculosis | 3hpx_b | P9WQB3 | 100.00 | 8.40E-51 | 5.80E-55 | 394.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | leuA2 LEPBI_I1108 |
leuA2 LEPBI_I1108 |
2.3.3.13 | Leptospira biflexa | 4ov4_a | B0SN40 | 100.00 | 5.40E-60 | 3.80E-64 | 460.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | BMEI1926 |
BMEI1926 |
4.1.3.4 | Brucella melitensis | 1ydn_a | Q8YEF2 | 100.00 | 2.00E-40 | 1.40E-44 | 309.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | dmpG |
4-hydroxy-2-oxovalerate aldolase (HOA) (EC 4.1.3.39) (4-hydroxy-2-keto-pentanoic acid aldolase) (4-hydroxy-2-oxopentanoate aldolase) |
4.1.3.39 | Pseudomonas sp. | 1nvm_a | P51016 | 100.00 | 3.20E-40 | 2.30E-44 | 314.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | pycA SAV1114 |
Pyruvate carboxylase (EC 6.4.1.1) |
6.4.1.1 | Staphylococcus aureus | 3hb9_a | A0A0H3JRU9 | 100.00 | 2.00E-41 | 1.40E-45 | 367.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | leuA LMOf2365_2010 |
2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase) |
2.3.3.13 | Listeria monocytogenes | 3ewb_x | Q71Y35 | 100.00 | 1.40E-42 | 1.00E-46 | 323.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | PC |
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) |
6.4.1.1 | Homo sapiens | Urea Cycle Disorder,Multiple Carboxylase Deficiency,Malignant Astrocytoma,Acute Porphyria,Methylmalonic Acidemia,Fructose-1,6-Bisphosphatase Deficiency,Body Mass Index Quantitative Trait Locus 11,Glutaric Acidemia I,Glycogen Storage Disease Ia,Lactic Acidosis,Nystagmus 6, Congenital, X-Linked,Propionic Acidemia,Primary Cutaneous Amyloidosis,Hyperinsulinemic Hypoglycemia, Familial, 6,Biotin Deficiency,Mitochondrial Complex Ii Deficiency, Nuclear Type 1,Biotinidase Deficiency,Holocarboxylase Synthetase Deficiency,Pyruvate Dehydrogenase E1-Alpha Deficiency,Pyruvate Carboxylase Deficiency |
3bg3_a | P11498 | ENSG00000173599 | PC | 100.00 | 1.30E-42 | 8.80E-47 | 357.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDL182W | LYS20 | SGDID:S000002341 | oadA-2 ERS013165_02612 |
oadA-2 ERS013165_02612 |
2.1.3.1,4.1.1.3, | Vibrio cholerae | 2nx9_a | Q6A1F6 | 100.00 | 6.70E-45 | 4.60E-49 | 357.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | yngG BSU18230 |
Hydroxymethylglutaryl-CoA lyase YngG (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase) |
4.1.3.4 | Bacillus subtilis | 1ydo_c | O34873 | 100.00 | 6.70E-39 | 4.70E-43 | 300.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | lys4 SPBC1105.02c |
Homocitrate synthase, mitochondrial (HCS) (EC 2.3.3.14) |
2.3.3.14 | Schizosaccharomyces pombe | 3ivs_b | Q9Y823 | 100.00 | 1.60E-64 | 1.10E-68 | 493.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | Mfla_1512 |
Mfla_1512 |
Methylobacillus flagellatus | 5ks8_c | Q1H157 | 100.00 | 7.50E-43 | 5.20E-47 | 355.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDL182W | LYS20 | SGDID:S000002341 | gsl-elong-A1 |
gsl-elong-A1 |
Brassica juncea | 6e1j_a | C5J4P1 | 100.00 | 3.80E-62 | 2.60E-66 | 481.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDL182W | LYS20 | SGDID:S000002341 | liuE PA2011 |
3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase (HIHG-CoA lyase) (HMG-CoA lyase) (EC 4.1.3.26) (EC 4.1.3.4) ((S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase) (3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase) |
4.1.3.26,4.1.3.4, | Pseudomonas aeruginosa | 2ftp_a | Q9I2A0 | 100.00 | 6.50E-41 | 4.60E-45 | 312.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | hsaF Rv3534c |
4-hydroxy-2-oxohexanoate aldolase (EC 4.1.3.43) (4-hydroxy-2-keto-pentanoic acid aldolase) (4-hydroxy-2-oxopentanoate aldolase) (4-hydroxy-2-oxovalerate aldolase) (HOA) (EC 4.1.3.39) |
4.1.3.39,4.1.3.43, | Mycobacterium tuberculosis | 4jn6_a | P9WMK5 | 100.00 | 8.30E-45 | 5.90E-49 | 346.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDL182W | LYS20 | SGDID:S000002341 | BVU_2661 |
BVU_2661 |
Bacteroides vulgatus | 3dxi_a | A6L3P9 | 100.00 | 7.70E-39 | 5.40E-43 | 300.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDL182W | LYS20 | SGDID:S000002341 | cimA LA_2350 |
(R)-citramalate synthase CimA (EC 2.3.1.182) (LiCMS) |
2.3.1.182 | Leptospira interrogans | 3ble_a | Q8F3Q1 | 100.00 | 4.00E-50 | 2.80E-54 | 381.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |