YDR062W LCB2 / SGDID:S000002469
SGD CSV
Disease Associated
Homo Sapiens
Mus Musculus
Danio Rerio
Drosophila Melanogaster
Caenorhabditis Elegans
Arabidopsis Thaliana
Escherichia Coli
Yeast Systematic Name Yeast Symbol SGDID Analog Name Analog Description EC Organism Disease Structure Uniprot Human ID Human Symbol HHsearch Probability HHsearch E_value HHsearch P_value HHsearch Score Flag Disease related Flag Homo sapiens Flag Mus musculus Flag Danio rerio Flag Drosophila melanogaster Flag Caenorhabditis elegans Flag Arabidopsis thaliana Flag Escherichia coli
YDR062W LCB2 SGDID:S000002469
PAT AAT MEE17 At2g22250 T26C19.9
Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase (AtAAT) (AtPPA-AT) (EC 2.6.1.1) (EC 2.6.1.78) (EC 2.6.1.79) (Protein MATERNAL EFFECT EMBRYO ARREST 17)
 2.6.1.1,2.6.1.78,2.6.1.79 Arabidopsis thaliana
5wmk_a Q9SIE1 99.40 6.70E-17 4.70E-21 166.70 0 0 0 0 0 0 1 0
YDR062W LCB2 SGDID:S000002469
PH0207
PH0207
 Pyrococcus horikoshii
1x0m_a O57946 99.70 5.00E-21 3.60E-25 193.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
lpg0604
lpg0604
 2.8.1.7 Legionella pneumophila
6c9e_b Q5ZXX6 99.30 1.90E-16 1.30E-20 160.40 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
bioF MSMEG_3189 MSMEI_3107
8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (KAPA synthase) (8-amino-7-ketopelargonate synthase) (Alpha-oxoamine synthase)
 2.3.1.47 Mycolicibacterium smegmatis
3wy7_d A0QX65 99.60 1.10E-19 7.70E-24 183.80 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
ARO8 YGL202W
Aromatic/aminoadipate aminotransferase 1 (2-aminoadipate aminotransferase) (EC 2.6.1.39) (2-aminoadipate transaminase) (Alpha-aminoadipate aminotransferase) (AadAT) (Aromatic amino acid aminotransferase 1) (EC 2.6.1.57) (Aromatic amino acid aminotransferase I) (Aromatic amino acid-requiring protein 8)
 2.6.1.39,2.6.1.57, Saccharomyces cerevisiae
4je5_b P53090 99.70 4.00E-21 2.80E-25 200.00 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
AADAT KAT2 KYAT2
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT) (2-aminoadipate aminotransferase) (2-aminoadipate transaminase) (EC 2.6.1.39) (Alpha-aminoadipate aminotransferase) (AadAT) (Kynurenine aminotransferase II) (Kynurenine--oxoglutarate aminotransferase II) (Kynurenine--oxoglutarate transaminase 2) (EC 2.6.1.7) (Kynurenine--oxoglutarate transaminase II)
 2.6.1.39,2.6.1.7, Homo sapiens
Detrusor Sphincter Dyssynergia,Disease Of Mental Health,Schizophrenia,Huntington Disease
 2r2n_a Q8N5Z0 ENSG00000109576 AADAT 99.60 1.90E-19 1.30E-23 183.30 1 1 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
agt
agt
 2.6.1.44 Thermococcus litoralis
2zc0_b Q9C4M4 99.50 6.40E-19 4.50E-23 178.00 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
RER070207001803
RER070207001803
 2.6.1.- Eubacterium rectale
3ele_b D0VX02 99.30 1.80E-16 1.20E-20 159.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
mfnC MJ0684
(5-formylfuran-3-yl)methyl phosphate transaminase (EC 2.6.1.108) (4-HFC-P:alanine aminotransferase)
 2.6.1.108 Methanocaldococcus jannaschii
2z61_a Q58097 99.30 1.50E-16 1.00E-20 158.20 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
ARO9 orf19.1237 CAALFM_C405560CA
ARO9 orf19.1237 CAALFM_C405560CA
 Candida albicans
6hnd_a A0A1D8PMC5 99.40 1.20E-17 8.50E-22 173.70 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
ALAS2 ALASE ASB
5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2)
 2.3.1.37 Homo sapiens
X-Linked Recessive Disease,Sideroblastic Anemia,Macrocytic Anemia,Hemochromatosis Type 2,X-Linked Cerebellar Ataxia,Porphyria,Hemoglobinopathy,Cutaneous Porphyria,Sickle Cell Disease,X-Linked Protoporphyria,Acute Porphyria,Deficiency Anemia,Porphyria, Acute Intermittent,Porphyria Cutanea Tarda,Variegate Porphyria,Microcytic Anemia,Coproporphyria, Hereditary,Protoporphyria, Erythropoietic, 1,Hemochromatosis, Type 1,Anemia, Sideroblastic, 1,Protoporphyria, Erythropoietic, X-Linked,Hypochromic Microcytic Anemia,X-Linked Monogenic Disease,Anemia, Sideroblastic, And Spinocerebellar Ataxia,Non-Syndromic X-Linked Intellectual Disability,Pyridoxine-Responsive Sideroblastic Anemia,Wieacker-Wolff Syndrome,Pearson Marrow-Pancreas Syndrome,Hyperferritinemia With Or Without Cataract
 6hrh_a P22557 ENSG00000158578 ALAS2 99.60 1.60E-20 1.10E-24 194.00 1 1 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
kbl CBU_0111
kbl CBU_0111
 2.3.1.29 Coxiella burnetii
3tqx_a Q83F40 99.50 4.40E-19 3.10E-23 178.60 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
CAWG_03814
CAWG_03814
 Candida albicans
6hnb_a C4YJ02 99.60 3.50E-20 2.50E-24 192.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
KYAT1 CCBL1
Kynurenine--oxoglutarate transaminase 1 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase) (EC 4.4.1.13) (Glutamine transaminase K) (GTK) (Glutamine--phenylpyruvate transaminase) (EC 2.6.1.64) (Kynurenine aminotransferase 1) (Kynurenine aminotransferase I) (KATI) (Kynurenine--oxoglutarate transaminase I)
 2.6.1.64,2.6.1.7,4.4.1.13 Homo sapiens
Schizophrenia
 3fvs_a Q16773 ENSG00000171097 KYAT1 99.40 5.20E-17 3.70E-21 164.80 1 1 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
SPT1 DRN02_007885
SPT1 DRN02_007885
 Sphingomonas paucimobilis
2jg2_a Q93UV0 99.60 1.20E-19 8.60E-24 184.40 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
GOT1
Aspartate aminotransferase, cytoplasmic (cAspAT) (EC 2.6.1.1) (EC 2.6.1.3) (Cysteine aminotransferase, cytoplasmic) (Cysteine transaminase, cytoplasmic) (cCAT) (Glutamate oxaloacetate transaminase 1) (Transaminase A)
 2.6.1.1,2.6.1.3, Sus scrofa
1ajs_a P00503 99.50 2.80E-18 1.90E-22 173.70 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
TAT
Tyrosine aminotransferase (TAT) (EC 2.6.1.5) (L-tyrosine:2-oxoglutarate aminotransferase)
 2.6.1.5 Homo sapiens
Herpes Simplex Virus Keratitis,Amino Acid Metabolic Disorder,Tyrosinemia,Tyrosinemia, Type Ii,Small Cell Sarcoma,Tyrosinemia, Type I,Tyrosinemia, Type Iii,Tyrosinosis,Human Immunodeficiency Virus Type 1,Palmoplantar Keratosis,Disseminated Intravascular Coagulation,Keratosis,Neu-Laxova Syndrome 2,Immune Deficiency Disease,Hawkinsinuria,Keratitis, Hereditary,Alkaptonuria
 3dyd_b P17735 ENSG00000198650 TAT 99.40 1.20E-17 8.40E-22 169.90 1 1 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
Aminotransferase
Aminotransferase
 Thermus thermophilus
1v2e_a Q75WK2 99.30 1.60E-16 1.20E-20 158.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
bioF Bmul_0373 BMULJ_02881
8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (KAPA synthase) (8-amino-7-ketopelargonate synthase)
 2.3.1.47 Burkholderia multivorans
5vnx_a A9AE46 99.60 2.80E-19 2.00E-23 179.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
iscS Rv3025c
IscS-like cysteine desulfurase (EC 2.8.1.7)
 2.8.1.7 Mycobacterium tuberculosis
4isy_b P9WQ71 99.40 5.50E-17 3.90E-21 163.30 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
GPT2 AAT2 ALT2
Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)
 2.6.1.2 Homo sapiens
Lymphangitis,Filarial Elephantiasis,Rare Genetic Intellectual Disability,Hereditary Spastic Paraplegia,Elephantiasis,Loiasis,Loeys-Dietz Syndrome 1,Microcephaly,Loeys-Dietz Syndrome 2,Cone-Rod Dystrophy 19,Loeys-Dietz Syndrome,Neu-Laxova Syndrome 2,Neurodevelopmental Disorder With Spastic Paraplegia And Microcephaly,Autosomal Recessive Non-Syndromic Intellectual Disability
 3ihj_a Q8TD30 ENSG00000166123 GPT2 99.40 7.90E-17 5.50E-21 167.10 1 1 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
TM_1131
TM_1131
 Thermotoga maritima
1vp4_a Q9X0L5 99.70 2.30E-21 1.60E-25 197.70 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
HEM1 CYD1 YDR232W YD9934.16
5-aminolevulinate synthase, mitochondrial (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-ALA synthase) (Delta-aminolevulinate synthase)
 2.3.1.37 Saccharomyces cerevisiae
5txr_a P09950 99.50 5.70E-19 3.90E-23 183.30 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
Kyat3 Ccbl2 Kat3
Kynurenine--oxoglutarate transaminase 3 (EC 2.6.1.7) (Cysteine-S-conjugate beta-lyase 2) (EC 4.4.1.13) (Kynurenine aminotransferase 3) (Kynurenine aminotransferase III) (KATIII) (Kynurenine--glyoxylate transaminase) (EC 2.6.1.63) (Kynurenine--oxoglutarate transaminase III)
 2.6.1.63,2.6.1.7,4.4.1.13 Mus musculus
3e2y_b Q71RI9 99.40 8.10E-17 5.70E-21 162.70 0 0 1 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
Swit_3900
Swit_3900
 2.3.1.50 Sphingomonas wittichii
2x8u_b A5VD79 99.50 2.60E-18 1.90E-22 173.90 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
sufS csdB ynhB b1680 JW1670
Cysteine desulfurase (EC 2.8.1.7) (Selenocysteine beta-lyase) (SCL) (Selenocysteine lyase) (EC 4.4.1.16) (Selenocysteine reductase)
 2.8.1.7,4.4.1.16, Escherichia coli
6o11_a P77444 99.40 7.70E-17 5.50E-21 162.30 0 0 0 0 0 0 0 1
YDR062W LCB2 SGDID:S000002469
Cgl0240
Aspartate aminotransferase (AspAT) (EC 2.6.1.1)
 2.6.1.1 Corynebacterium glutamicum
3ppl_b Q8NTR2 99.30 1.40E-16 1.00E-20 161.80 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
cqsA VC_A0523
CAI-1 autoinducer synthase (EC 2.3.-.-) (Cholerae quorum-sensing autoinducer)
 2.3.-.- Vibrio cholerae
2wka_a Q9KM65 99.50 3.80E-19 2.70E-23 178.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
vioD SLAV_37385
vioD SLAV_37385
 4.3.2.- Streptomyces lavendulae
4m2k_a G9MBV4 99.30 8.60E-17 6.00E-21 162.20 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
bioF FTT_0936c
bioF FTT_0936c
 2.3.1.47 Francisella tularensis
4iw7_a Q5NGB3 99.50 3.90E-19 2.70E-23 179.20 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
SAMN05216234_11013
SAMN05216234_11013
 Hydrogenimonas thermophila
5zss_a A0A1I5NEH3 99.40 5.90E-17 4.20E-21 163.90 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
ALA2
Alanine aminotransferase 2 (ALAAT-2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)
 2.6.1.2 Hordeum vulgare
3tcm_a P52894 99.40 7.30E-18 5.10E-22 175.00 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
SMU_24
SMU_24
 2.6.1.- Streptococcus mutans
4my5_a Q8DWM1 99.30 1.10E-16 7.70E-21 160.60 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
Kynurenine aminotransferase (EC 2.6.1.-) (EC 2.6.1.63) (EC 2.6.1.7) (AeKAT)
 Aedes aegypti
1yiz_b Q95VY4 99.40 1.10E-17 7.90E-22 170.20 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
Apre_1502
Apre_1502
 Anaerococcus prevotii
4emy_b C7REB0 99.40 7.50E-17 5.30E-21 163.10 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
RSP_3437
RSP_3437
 Rhodobacter sphaeroides
3nra_a Q3IWP3 99.50 6.00E-18 4.20E-22 170.70 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
BD94_3973
BD94_3973
 Elizabethkingia anophelis
5vpr_a A0A077EMQ8 99.30 1.70E-16 1.20E-20 160.20 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
hemA RCAP_rcc01447
5-aminolevulinate synthase (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-ALA synthase) (Delta-aminolevulinate synthase)
 2.3.1.37 Rhodobacter capsulatus
2bwn_a P18079 99.60 1.80E-20 1.30E-24 189.30 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
HKT 1272658 3hkt AgaP_AGAP010387
3-hydroxykynurenine transaminase (EC 2.6.1.63) (AgHKT) (Alanine--glyoxylate aminotransferase) (EC 2.6.1.44)
 2.6.1.44,2.6.1.63, Anopheles gambiae
2ch1_b Q7PRG3 99.40 6.00E-17 4.20E-21 162.40 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
spl1 RAF_ORF0675
spl1 RAF_ORF0675
 2.8.1.7 Rickettsia africae
4ixo_a C3PNQ7 99.40 4.00E-17 2.80E-21 162.90 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
aatA R02325 SMc01578
Aspartate/prephenate aminotransferase (AspAT / PAT) (EC 2.6.1.1) (EC 2.6.1.79) (Transaminase A)
 2.6.1.1,2.6.1.79, Rhizobium meliloti
6f77_b Q02635 99.40 6.90E-17 4.90E-21 162.50 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
avtA STM3665
avtA STM3665
 2.6.1.66 Salmonella typhimurium
3g7q_a Q8ZL86 99.40 1.60E-17 1.10E-21 168.40 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
bioF b0776 JW0759
8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (KAPA synthase) (8-amino-7-ketopelargonate synthase)
 2.3.1.47 Escherichia coli
2g6w_a P12998 99.50 4.90E-18 3.50E-22 169.90 0 0 0 0 0 0 0 1
YDR062W LCB2 SGDID:S000002469
lysN TT_C0043
2-aminoadipate transaminase (EC 2.6.1.39) (2-aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AAA-AT) (AadAT)
 2.6.1.39 Thermus thermophilus
2zyj_a Q72LL6 99.70 4.60E-21 3.20E-25 193.40 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
spt bioF_1 NCTC11343_02561 SPHINGO8BC_150128
spt bioF_1 NCTC11343_02561 SPHINGO8BC_150128
 2.3.1.-,2.3.1.47,2.3.1.50 Sphingobacterium multivorum
3a2b_a A7BFV6 99.50 3.30E-19 2.30E-23 179.70 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
phnW STM0431
2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT)
 2.6.1.37 Salmonella typhimurium
1m32_b P96060 99.30 1.40E-16 1.00E-20 157.30 0 0 0 0 0 0 0 0
YDR062W LCB2 SGDID:S000002469
aspC
aspC
 2.6.1.- Phormidium lapideum
1j32_b Q8RR70 99.40 1.70E-17 1.20E-21 166.20 0 0 0 0 0 0 0 0