Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YDR268W | MSW1 | SGDID:S000002676 | tyrS ABSDF0019 |
tyrS ABSDF0019 |
6.1.1.1 | Acinetobacter baumannii | 6bqy_b | B0VML7 | 100.00 | 2.80E-40 | 1.80E-44 | 293.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | WARS1 IFI53 WARS WRS |
Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS] |
6.1.1.2 | Homo sapiens | Robinow Syndrome, Autosomal Recessive 1,Noonan Syndrome 1,Charcot-Marie-Tooth Disease,Neuronopathy, Distal Hereditary Motor, Type Ix,Charcot-Marie-Tooth Disease, Axonal, Type 2u,Developmental And Epileptic Encephalopathy 29 |
1o5t_a | P23381 | ENSG00000140105 | WARS1 | 100.00 | 1.00E-43 | 6.50E-48 | 312.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR268W | MSW1 | SGDID:S000002676 | PF3D7_1336900 |
PF3D7_1336900 |
6.1.1.2 | Plasmodium falciparum | 4j75_a | Q8IDW3 | 100.00 | 3.50E-45 | 2.20E-49 | 322.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS PH1011 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Pyrococcus horikoshii | 2cyc_a | O58739 | 100.00 | 4.20E-43 | 2.70E-47 | 309.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | WRS1 YOL097C HRE432 |
Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Saccharomyces cerevisiae | 2ip1_a | Q12109 | 100.00 | 4.60E-44 | 2.90E-48 | 317.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS APE_2461.1 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Aeropyrum pernix | 3a04_a | Q9Y924 | 100.00 | 2.50E-45 | 1.60E-49 | 321.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | BD94_0195 |
BD94_0195 |
Elizabethkingia anophelis | 6mtk_a | A0A077EER2 | 100.00 | 3.10E-53 | 1.90E-57 | 367.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR268W | MSW1 | SGDID:S000002676 | cyt-18 B18P24.070 NCU03030 |
Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Neurospora crassa | 1y42_x | P12063 | 100.00 | 1.10E-42 | 6.90E-47 | 304.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | YARS MIMI_L124 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Acanthamoeba polyphaga | 2j5b_a | Q5UPJ7 | 100.00 | 3.90E-47 | 2.40E-51 | 331.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | LDBPK_141460 |
LDBPK_141460 |
Leishmania donovani | 5usf_a | E9BC28 | 100.00 | 3.00E-40 | 1.90E-44 | 310.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR268W | MSW1 | SGDID:S000002676 | trpS MPN_265 MP568 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Mycoplasma pneumoniae | 2yy5_b | P75510 | 100.00 | 1.00E-53 | 6.30E-58 | 373.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS TM_0492 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Thermotoga maritima | 2g36_a | Q9WYW2 | 100.00 | 2.90E-52 | 1.80E-56 | 364.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Geobacillus stearothermophilus | 1d2r_c | P00953 | 100.00 | 1.90E-53 | 1.20E-57 | 368.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS NGO_1045 |
trpS NGO_1045 |
6.1.1.2 | Neisseria gonorrhoeae | 5tev_a | Q5F7X0 | 100.00 | 5.10E-53 | 3.20E-57 | 368.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | EHI_110680 |
EHI_110680 |
Entamoeba histolytica | 3hzr_c | C4LUB5 | 100.00 | 5.60E-45 | 3.50E-49 | 319.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR268W | MSW1 | SGDID:S000002676 | YARS1 YARS |
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed] |
6.1.1.1 | Homo sapiens | Non-Alcoholic Fatty Liver Disease,Robinow Syndrome, Autosomal Recessive 1,Charcot-Marie-Tooth Disease, Dominant Intermediate C,Neuromuscular Disease,Fatty Liver Disease,Infantile Liver Failure Syndrome,Charcot-Marie-Tooth Disease, Axonal, Type 2d,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Retinal Degeneration,Intellectual Disability - Hypoplastic Corpus Callosum - Preauricular Tag,Hyperinsulinemic Hypoglycemia,Charcot-Marie-Tooth Disease,Fatty Liver Disease, Nonalcoholic 1,Charcot-Marie-Tooth Disease, Axonal, Type 2n,Tooth Disease,Rigid Spine Muscular Dystrophy 1,Charcot-Marie-Tooth Disease, Demyelinating, Type 1b,Charcot-Marie-Tooth Disease And Deafness,Visceral Steatosis, Congenital,Charcot-Marie-Tooth Disease, Recessive Intermediate B,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive,Combined Oxidative Phosphorylation Deficiency 8,Charcot-Marie-Tooth Disease Intermediate Type,Charcot-Marie-Tooth Disease, Axonal, Type 2u,Charcot-Marie-Tooth Disease, Dominant Intermediate B,Charcot-Marie-Tooth Disease, Dominant Intermediate A,Developmental And Epileptic Encephalopathy 29,Perrault Syndrome,Usher Syndrome, Type Iiib,Charcot-Marie-Tooth Disease, Axonal, Type 2e,Charcot-Marie-Tooth Disease, Dominant Intermediate D,Neuronopathy, Distal Hereditary Motor, Type Va |
5thh_a | P54577 | ENSG00000134684 | YARS1 | 100.00 | 1.70E-43 | 1.10E-47 | 307.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR268W | MSW1 | SGDID:S000002676 | trpS2 trpSII DR_1093 |
Tryptophan--tRNA ligase 2 (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase 2) (TrpRS 2) (Tryptophanyl-tRNA synthetase II) (TrpRS II) |
6.1.1.2 | Deinococcus radiodurans | 1yi8_a | Q9RVD6 | 100.00 | 1.10E-54 | 7.10E-59 | 379.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | ECU11_0530 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Encephalitozoon cuniculi | 3tze_a | O96771 | 100.00 | 7.00E-44 | 4.40E-48 | 314.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | ANIA_01709 |
ANIA_01709 |
6.1.1.1 | Emericella nidulans | 5ihx_a | Q5BCM1 | 100.00 | 1.70E-40 | 1.00E-44 | 291.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS NGK_0091 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Neisseria gonorrhoeae | 6otj_b | B4RP13 | 100.00 | 2.80E-40 | 1.80E-44 | 295.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | TYS1 MGM104 YGR185C G7522 |
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Saccharomyces cerevisiae | 2dlc_x | P36421 | 100.00 | 7.90E-51 | 4.90E-55 | 359.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS VC_2623 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Vibrio cholerae | 3sz3_a | Q9KNV7 | 100.00 | 5.50E-54 | 3.50E-58 | 374.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS PH1921 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Pyrococcus horikoshii | 3jxe_a | O59584 | 100.00 | 4.50E-51 | 2.80E-55 | 360.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS MJ0389 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Methanocaldococcus jannaschii | 4nx2_a | Q57834 | 100.00 | 7.00E-43 | 4.40E-47 | 299.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS APE_2074.1 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Aeropyrum pernix | 2cya_a | Q9YA64 | 100.00 | 5.70E-47 | 3.60E-51 | 332.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | GL50803_003032 GL50803_3032 |
GL50803_003032 GL50803_3032 |
6.1.1.2 | Giardia intestinalis | 3foc_a | A8B8N3 | 100.00 | 1.90E-43 | 1.20E-47 | 312.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS BSU11420 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Bacillus subtilis | 3prh_a | P21656 | 100.00 | 2.60E-56 | 1.70E-60 | 392.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | PF3D7_0807900 |
PF3D7_0807900 |
6.1.1.1 | Plasmodium falciparum | 3vgj_b | Q8IAR7 | 100.00 | 1.00E-48 | 6.60E-53 | 343.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS AF_0776 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Archaeoglobus fulgidus | 2cyb_a | O29482 | 100.00 | 6.30E-43 | 4.00E-47 | 302.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS TT_C1033 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Thermus thermophilus | 1h3e_a | P83453 | 100.00 | 1.00E-38 | 6.50E-43 | 285.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | YARS2 CGI-04 |
Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Homo sapiens | Sideroblastic Anemia,Myopathy, Lactic Acidosis, And Sideroblastic Anemia,Myopathy,Charcot-Marie-Tooth Disease, Dominant Intermediate C,Mitochondrial Myopathy,Combined Oxidative Phosphorylation Deficiency 12,Charcot-Marie-Tooth Disease, Axonal, Type 2d,Autosomal Dominant Distal Hereditary Motor Neuronopathy,Optic Atrophy 1,Mitochondrial Disorders,Charcot-Marie-Tooth Disease,Charcot-Marie-Tooth Disease, Axonal, Type 2n,Rigid Spine Muscular Dystrophy 1,Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2,Charcot-Marie-Tooth Disease, Recessive Intermediate B,Lactic Acidosis,Optic Atrophy 5,Combined Oxidative Phosphorylation Deficiency 20,Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive,Charcot-Marie-Tooth Disease Intermediate Type,Sideroblastic Anemia With B-Cell Immunodeficiency, Periodic Fevers, And Developmental Delay,Encephalopathy Due To Defective Mitochondrial And Peroxisomal Fission 1,Perrault Syndrome,Mitochondrial Dna Depletion Syndrome 4a,Myopathy, Lactic Acidosis, And Sideroblastic Anemia 3,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes,Pearson Marrow-Pancreas Syndrome,Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1,Neuronopathy, Distal Hereditary Motor, Type Va |
2pid_b | Q9Y2Z4 | ENSG00000139131 | YARS2 | 100.00 | 5.70E-43 | 3.60E-47 | 304.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR268W | MSW1 | SGDID:S000002676 | tyrS BD94_1246 |
tyrS BD94_1246 |
Elizabethkingia anophelis | 6n0w_a | A0A077EBU6 | 100.00 | 2.80E-41 | 1.80E-45 | 303.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR268W | MSW1 | SGDID:S000002676 | tyrS b1637 JW1629 |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Escherichia coli | 1vbm_b | P0AGJ9 | 100.00 | 5.70E-42 | 3.60E-46 | 295.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS TTHA1227 |
trpS TTHA1227 |
6.1.1.2 | Thermus thermophilus | 2el7_a | Q5SIY7 | 100.00 | 2.60E-53 | 1.60E-57 | 369.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | CPC735_063460 |
CPC735_063460 |
6.1.1.1 | Coccidioides posadasii | 5ijx_a | C5P455 | 100.00 | 1.00E-41 | 6.40E-46 | 298.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS Z4737 ECs4226 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Escherichia coli | 5v0i_a | P67589 | 100.00 | 6.90E-54 | 4.30E-58 | 373.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YDR268W | MSW1 | SGDID:S000002676 | WARS2 |
Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Homo sapiens | Robinow Syndrome, Autosomal Recessive 1,Bulbar Polio,Trichohepatoenteric Syndrome 1,Neurodevelopmental Disorder, Mitochondrial, With Abnormal Movements And Lactic Acidosis, With Or Without Seizures,Spastic Quadriplegia,Lactic Acidosis,Perrault Syndrome,Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes |
5ekd_b | Q9UGM6 | ENSG00000116874 | WARS2 | 100.00 | 3.30E-55 | 2.10E-59 | 382.40 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR268W | MSW1 | SGDID:S000002676 | tyrS |
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) |
6.1.1.1 | Geobacillus stearothermophilus | 4ts1_a | P00952 | 100.00 | 7.10E-42 | 4.50E-46 | 294.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | cgd7_1490 |
cgd7_1490 |
6.1.1.2 | Cryptosporidium parvum | 3hv0_b | Q5CYP8 | 100.00 | 3.60E-44 | 2.30E-48 | 315.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | tyrS HPG27_731 |
tyrS HPG27_731 |
6.1.1.1 | Helicobacter pylori | 6byq_a | B5Z7D7 | 100.00 | 6.20E-39 | 3.90E-43 | 284.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS HI_0637 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Haemophilus influenzae | 6dfu_a | P43835 | 100.00 | 4.60E-55 | 2.90E-59 | 380.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS Cj0388 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Campylobacter jejuni | 3tzl_a | Q9PIB4 | 100.00 | 3.60E-51 | 2.30E-55 | 354.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | trpS CT_585 |
Tryptophan--tRNA ligase (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS) |
6.1.1.2 | Chlamydia trachomatis | 6ncr_a | O84589 | 100.00 | 9.00E-55 | 5.70E-59 | 379.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR268W | MSW1 | SGDID:S000002676 | Tb927.3.5580 |
Tb927.3.5580 |
6.1.1.2 | Trypanosoma brucei | 3i05_b | Q580R7 | 100.00 | 2.20E-44 | 1.40E-48 | 316.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |