Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
YDR441C | APT2 | SGDID:S000002849 | APRT |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Homo sapiens | Purine-Pyrimidine Metabolic Disorder,Urolithiasis,Dihydroxyadeninuria,Morquio Syndrome,Congenital Muscular Dystrophy-Dystroglycanopathy Type A11,Mucopolysaccharidosis-Plus Syndrome,Cystinuria,Mucopolysaccharidosis Iv,Gout,Purine Nucleoside Phosphorylase Deficiency,Nephrolithiasis, Calcium Oxalate,Interstitial Nephritis,Nephrolithiasis,Hereditary Xanthinuria,Ureterolithiasis,Retinitis Pigmentosa 56,Lesch-Nyhan Syndrome,Lynch Syndrome,Phosphoribosylpyrophosphate Synthetase Superactivity,Arts Syndrome,Adenine Phosphoribosyltransferase Deficiency,Xanthinuria,Molybdenum Cofactor Deficiency, Complementation Group A,Mucopolysaccharidosis, Type Iva |
6fch_a | P07741 | ENSG00000198931 | APRT | 99.60 | 7.80E-21 | 4.80E-25 | 123.10 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR441C | APT2 | SGDID:S000002849 | apt FTT_0078 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Francisella tularensis | 5yw2_b | Q5NII9 | 99.60 | 1.60E-20 | 1.00E-24 | 121.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | xpt BSU22070 |
Xanthine phosphoribosyltransferase (XPRTase) (EC 2.4.2.22) |
2.4.2.22 | Bacillus subtilis | 1y0b_d | P42085 | 99.40 | 6.50E-17 | 4.00E-21 | 106.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE SMU_1221 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Streptococcus mutans | 3dez_a | Q8DTV2 | 99.40 | 7.10E-17 | 4.40E-21 | 109.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | LDBPK_160560 |
LDBPK_160560 |
2.4.2.10,4.1.1.23, | Leishmania donovani | 3qw4_c | E9BCQ9 | 99.30 | 3.20E-16 | 2.00E-20 | 114.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | Tb927.7.1780 |
Tb927.7.1780 |
2.4.2.7 | Trypanosoma brucei | 5vn4_a | Q57V32 | 99.40 | 1.90E-17 | 1.20E-21 | 112.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE APE_2349.1 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Aeropyrum pernix | 2yzk_a | Q9Y9D8 | 99.40 | 2.90E-17 | 1.80E-21 | 106.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | LACZ |
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGPRT) (HGXPRT) (HGXPRTase) (EC 2.4.2.22) (EC 2.4.2.8) |
2.4.2.22,2.4.2.8, | Plasmodium falciparum | 1cjb_c | P20035 | 99.10 | 2.30E-14 | 1.40E-18 | 96.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | hpt LIC_13438 |
hpt LIC_13438 |
2.4.2.8 | Leptospira interrogans | 4qri_a | Q72LV5 | 99.00 | 3.90E-14 | 2.40E-18 | 93.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE BCAL0204 |
pyrE BCAL0204 |
2.4.2.10 | Burkholderia cenocepacia | 4ohc_b | B4E589 | 99.40 | 4.60E-17 | 2.90E-21 | 109.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | hpt hprT Rv3624c MTCY15C10.28 |
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) |
2.4.2.8 | Mycobacterium tuberculosis | 4rhx_b | P9WHQ9 | 99.10 | 9.00E-15 | 5.60E-19 | 96.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE VC_0211 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Vibrio cholerae | 3n2l_d | Q9KVD5 | 99.40 | 3.80E-17 | 2.40E-21 | 110.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | UMPS OK/SW-cl.21 |
Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (EC 4.1.1.23) (OMPdecase)] |
2.4.2.10,4.1.1.23, | Homo sapiens | Gastroesophageal Adenocarcinoma,Megaloblastic Anemia,Colorectal Cancer,Gastric Cancer,Arts Syndrome,Pyrimidine Metabolic Disorder,Adenine Phosphoribosyltransferase Deficiency,Charcot-Marie-Tooth Disease, X-Linked Recessive, 5,Orotic Aciduria,Postaxial Acrofacial Dysostosis |
2wns_a | P11172 | ENSG00000114491 | UMPS | 99.40 | 1.60E-17 | 9.80E-22 | 109.70 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
YDR441C | APT2 | SGDID:S000002849 | apt YPTB0991 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Yersinia pseudotuberculosis | 5b6h_a | Q66DQ2 | 99.60 | 6.30E-20 | 3.90E-24 | 119.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | E8M63_03605 NCTC13805_02457 WHOF_00431 WHOF_02526C |
E8M63_03605 NCTC13805_02457 WHOF_00431 WHOF_02526C |
Neisseria gonorrhoeae | 5vog_a | A0A1D3HIA2 | 99.20 | 1.30E-15 | 8.20E-20 | 98.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR441C | APT2 | SGDID:S000002849 | apt b0469 JW0458 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Escherichia coli | 2dy0_b | P69503 | 99.60 | 8.70E-20 | 5.40E-24 | 119.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE SPy_0901 M5005_Spy0704 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Streptococcus pyogenes | 2aee_a | Q9A076 | 99.30 | 1.20E-16 | 7.40E-21 | 105.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | HGPRT |
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) |
2.4.2.8 | Schistosoma mansoni | 5ipf_a | P09383 | 99.10 | 3.20E-14 | 2.00E-18 | 96.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | TTHA1614 |
TTHA1614 |
Thermus thermophilus | 5zgo_b | Q5SHW6 | 99.40 | 5.00E-17 | 3.10E-21 | 105.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR441C | APT2 | SGDID:S000002849 | APT1 YML022W |
Adenine phosphoribosyltransferase 1 (APRT 1) (EC 2.4.2.7) |
2.4.2.7 | Saccharomyces cerevisiae | 1g2q_b | P49435 | 99.60 | 7.80E-21 | 4.90E-25 | 124.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | oprt |
oprt |
2.4.2.10 | Plasmodium falciparum | 4fym_c | Q8N0R1 | 99.30 | 4.90E-16 | 3.00E-20 | 106.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | HPRT1 HPRT |
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) |
2.4.2.8 | Homo sapiens | X-Linked Recessive Disease,Retinitis Pigmentosa,Connective Tissue Disease,Hyperuricemia,Purine-Pyrimidine Metabolic Disorder,Deafness, Autosomal Recessive 40,Urolithiasis,Tubulointerstitial Kidney Disease, Autosomal Dominant, 1,Movement Disease,Cataract 34, Multiple Types,Tetrahydrobiopterin Deficiency,Leukemia, Acute Lymphoblastic,Gout,Dystonia,Purine Nucleoside Phosphorylase Deficiency,Cockayne Syndrome,Aplastic Anemia,Colorectal Cancer,Parkinson Disease 1, Autosomal Dominant,Nephrolithiasis,Microcephaly,Cataract 4, Multiple Types,Teratocarcinoma,Deficiency Anemia,Xeroderma Pigmentosum, Variant Type,Fanconi Anemia, Complementation Group A,Deafness, Autosomal Recessive 55,Skin Carcinoma,Disease Of Mental Health,Lesch-Nyhan Syndrome,Hyperuricemia, Hprt-Related,Myasthenic Syndrome, Congenital, 12,Retinitis Pigmentosa 23,Fragile X Syndrome,Phosphoribosylpyrophosphate Synthetase Superactivity,Inflammatory Bowel Disease,Nephrolithiasis, Uric Acid,X-Linked Monogenic Disease,Inflammatory Bowel Disease 16,Arts Syndrome,Hypothyroidism, Congenital, Nongoitrous, 6,Neuropathy, Hereditary Sensory And Autonomic, Type Viii,Adenine Phosphoribosyltransferase Deficiency,Immunodeficiency With Hyper-Igm, Type 1,Rett Syndrome,Ataxia-Telangiectasia,Bloom Syndrome |
1d6n_a | P00492 | 99.10 | 6.50E-15 | 4.10E-19 | 97.60 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
YDR441C | APT2 | SGDID:S000002849 | pyrE FTT_0437c |
pyrE FTT_0437c |
2.4.2.10 | Francisella tularensis | 3mjd_a | Q5NHL5 | 99.40 | 8.50E-17 | 5.30E-21 | 108.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | purR yabI BSU00470 |
Pur operon repressor |
Bacillus subtilis | 1o57_a | P37551 | 99.30 | 1.70E-16 | 1.00E-20 | 110.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR441C | APT2 | SGDID:S000002849 | pyrE BA_4021 GBAA_4021 BAS3733 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Bacillus anthracis | 3m3h_a | Q81WF6 | 99.40 | 2.40E-17 | 1.50E-21 | 110.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | apt Rmar_0813 |
apt Rmar_0813 |
2.4.2.7 | Rhodothermus marinus | 4m0k_a | D0MGF4 | 99.70 | 4.40E-22 | 2.70E-26 | 131.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | LDHU3_26.0190 |
LDHU3_26.0190 |
2.4.2.7 | Leishmania donovani | 1qb7_a | Q27679 | 99.40 | 1.80E-17 | 1.10E-21 | 111.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | PRTFDC1 HHGP |
Phosphoribosyltransferase domain-containing protein 1 |
Homo sapiens | Purine-Pyrimidine Metabolic Disorder,Acute Laryngitis,Dissociative Amnesia,Lesch-Nyhan Syndrome |
2jbh_a | Q9NRG1 | ENSG00000099256 | PRTFDC1 | 99.10 | 1.90E-14 | 1.20E-18 | 96.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
YDR441C | APT2 | SGDID:S000002849 | URA5 PYR5 YML106W YM8339.13 |
Orotate phosphoribosyltransferase 1 (OPRT 1) (OPRTase 1) (EC 2.4.2.10) |
2.4.2.10 | Saccharomyces cerevisiae | 2ps1_a | P13298 | 99.40 | 1.80E-17 | 1.10E-21 | 110.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE DIP2097 |
pyrE DIP2097 |
2.4.2.10 | Corynebacterium diphtheriae | 2p1z_b | Q6NF12 | 99.40 | 3.20E-17 | 2.00E-21 | 106.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | apt Teth39_1027 |
Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) |
2.4.2.7 | Thermoanaerobacter pseudethanolicus | 4lza_b | B0K969 | 99.60 | 1.90E-20 | 1.20E-24 | 122.90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE umpA Rv0382c MTV036.17c |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Mycobacterium tuberculosis | 5hkl_b | P9WHK9 | 99.50 | 2.40E-18 | 1.50E-22 | 112.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | VC_0585 |
VC_0585 |
2.4.2.8 | Vibrio cholerae | 3ohp_a | Q9KUD7 | 99.00 | 4.00E-14 | 2.50E-18 | 91.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE b3642 JW3617 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Escherichia coli | 1oro_a | P0A7E3 | 99.40 | 5.70E-17 | 3.50E-21 | 107.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |||
YDR441C | APT2 | SGDID:S000002849 | TTHA1613 |
TTHA1613 |
Thermus thermophilus | 1vch_a | Q5SHW7 | 99.30 | 1.20E-16 | 7.60E-21 | 102.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
YDR441C | APT2 | SGDID:S000002849 | pyrR BSU15470 |
Bifunctional protein PyrR [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase (UPRTase) (EC 2.4.2.9)] |
2.4.2.9 | Bacillus subtilis | 1a3c_a | P39765 | 99.20 | 2.00E-15 | 1.20E-19 | 96.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | pyrE HP_1257 |
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) |
2.4.2.10 | Helicobacter pylori | 4paw_a | P56162 | 99.30 | 2.70E-16 | 1.70E-20 | 105.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
YDR441C | APT2 | SGDID:S000002849 | gpT-2 SSO2424 |
gpT-2 SSO2424 |
2.4.2.- | Saccharolobus solfataricus | 5bqo_d | Q97W22 | 99.10 | 9.50E-15 | 5.90E-19 | 94.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |