| Yeast Systematic Name | Yeast Symbol | SGDID | Analog Name | Analog Description | EC | Organism | Disease | Structure | Uniprot | Human ID | Human Symbol | HHsearch Probability | HHsearch E_value | HHsearch P_value | HHsearch Score | Flag Disease related | Flag Homo sapiens | Flag Mus musculus | Flag Danio rerio | Flag Drosophila melanogaster | Flag Caenorhabditis elegans | Flag Arabidopsis thaliana | Flag Escherichia coli |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| YEL016C | NPP2 | SGDID:S000000742 | phnA SM_b21538 |
phnA SM_b21538 |
3.6.1.9 | Rhizobium meliloti | 3szy_a | Q92UV8 | 99.90 | 4.60E-29 | 3.00E-33 | 241.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | SPOA0121 |
SPOA0121 |
Ruegeria pomeroyi | 4upi_a | Q5LLA5 | 99.80 | 3.50E-24 | 2.20E-28 | 214.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | SPO3593 |
SPO3593 |
Ruegeria pomeroyi | 4upl_a | Q5LMH0 | 99.80 | 2.70E-24 | 1.70E-28 | 215.10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | Enpp2 Atx Npps2 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD) |
3.1.4.39 | Rattus norvegicus | 5dlt_a | Q64610 | 99.90 | 5.80E-33 | 3.70E-37 | 289.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | ENPP7 UNQ3077/PRO9912 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase) |
3.1.4.12 | Homo sapiens | Colorectal Cancer,Familial Adenomatous Polyposis |
5tcd_a | Q6UWV6 | ENSG00000182156 | ENPP7 | 99.90 | 1.30E-31 | 8.20E-36 | 258.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | BT_4656 |
N-acetylglucosamine-6-O-sulfatase (EC 3.1.6.-) |
3.1.6.- | Bacteroides thetaiotaomicron | 5g2v_a | Q89YS5 | 99.70 | 6.30E-23 | 4.00E-27 | 203.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | BT_1596 |
Delta 4,5-hexuronate-2-O-sulfatase (EC 3.1.6.-) |
3.1.6.- | Bacteroides thetaiotaomicron | 3b5q_b | Q8A7C8 | 99.80 | 8.40E-24 | 5.40E-28 | 207.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | Enpp6 |
Glycerophosphocholine cholinephosphodiesterase ENPP6 (GPC-Cpde) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 6) (E-NPP 6) (NPP-6) |
3.1.4.38 | Mus musculus | 5egh_a | Q8BGN3 | 99.90 | 7.10E-31 | 4.50E-35 | 254.10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | XAC2824 |
XAC2824 |
Xanthomonas axonopodis | 2gso_a | Q8PIS1 | 99.90 | 3.80E-32 | 2.40E-36 | 260.20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | SPOA0390 |
SPOA0390 |
Ruegeria pomeroyi | 4upk_c | Q5LKJ1 | 99.70 | 5.20E-23 | 3.30E-27 | 204.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | Enpp5 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) |
3.1.-.- | Mus musculus | 5veo_a | Q9EQG7 | 99.90 | 7.80E-32 | 5.00E-36 | 259.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | pafA |
Alkaline phosphatase PafA (AP PafA) (EC 3.1.3.1) |
3.1.3.1 | Elizabethkingia meningoseptica | 5tj3_a | Q9KJX5 | 99.90 | 8.20E-28 | 5.30E-32 | 238.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | Enpp2 Npps2 Pdnp2 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD) |
3.1.4.39 | Mus musculus | 3nkm_a | Q9R1E6 | 99.90 | 4.00E-33 | 2.60E-37 | 290.50 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | ENPP5 UNQ550/PRO1107 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) |
3.1.-.- | Homo sapiens | Ceroid Lipofuscinosis, Neuronal, 6 |
5vem_b | Q9UJA9 | ENSG00000112796 | ENPP5 | 99.90 | 6.30E-33 | 4.00E-37 | 267.20 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | ENPP4 KIAA0879 NPP4 |
Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) |
3.6.1.29 | Homo sapiens | 4lqy_a | Q9Y6X5 | ENSG00000001561 | ENPP4 | 99.90 | 2.20E-30 | 1.40E-34 | 248.40 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| YEL016C | NPP2 | SGDID:S000000742 | BN863_22250 |
Bifunctional sulfatase/alpha-L-rhamnosidase (P36_GH78/S1_25) [Includes: Ulvan-active sulfatase (EC 3.1.6.-) (Sulfatase family S1 subfamily 25 protein P36) (P36_S1_25); Alpha-L-rhamnosidase (EC 3.2.1.40) (Glycosyl hydrolase 78 family protein P36) (P36_GH78) (Polysaccharide utilization locus H protein P36) (PUL H protein P36)] |
3.2.1.40 | Formosa agariphila | 6hr5_a | T2KM26 | 99.70 | 2.00E-22 | 1.30E-26 | 196.60 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | BN863_22070 |
Ulvan-active sulfatase (EC 3.1.6.-) (Arylsulfatase) (Polysaccharide utilization locus H protein P18) (PUL H protein P18) (Sulfatase family S1 subfamily 7 protein P18) (P18_S1_7) |
3.1.6.- | Formosa agariphila | 6hhm_a | T2KPK5 | 99.80 | 1.50E-24 | 9.30E-29 | 212.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | atsA PA0183 |
Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase) |
3.1.6.1 | Pseudomonas aeruginosa | 1hdh_a | P51691 | 99.80 | 6.80E-24 | 4.40E-28 | 210.40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | phnA |
Phosphonoacetate hydrolase (EC 3.11.1.2) |
3.11.1.2 | Pseudomonas fluorescens | 1ei6_a | Q51782 | 99.90 | 7.80E-28 | 5.00E-32 | 231.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | pehA |
Multifunctional alkaline phosphatase superfamily protein PehA (Phosphodiesterase) (EC 3.1.4.-) (Phosphonate ester hydrolase) (PEH) (EC 3.1.-.-) (Phosphonate monoester hydrolase) (BcPMH) (EC 3.1.3.-) (Sulfuric ester hydrolase) (EC 3.1.6.-) |
3.1.-.-,3.1.3.-,3.1.4.-,3.1.6.-, | Trinickia caryophylli | 2w8s_d | Q45087 | 99.70 | 9.10E-23 | 5.80E-27 | 203.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | pRL90232 |
Multifunctional alkaline phosphatase superfamily protein pRL90232 (Phosphodiesterase) (EC 3.1.4.-) (Phosphonate monoester hydrolase) (RlPMH) (EC 3.1.3.-) |
3.1.3.-,3.1.4.-, | Rhizobium leguminosarum | 2vqr_a | Q1M964 | 99.70 | 2.70E-22 | 1.70E-26 | 199.50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | SGSH HSS |
N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) |
3.10.1.1 | Homo sapiens | Sphingolipidosis,Pathologic Nystagmus,Kluver-Bucy Syndrome,Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Mucopolysaccharidosis Iv,Fundus Dystrophy,Tay-Sachs Disease,Diarrhea,Lysosomal Storage Disease,Mucopolysaccharidoses,Pityriasis Rubra Pilaris,Gm1 Gangliosidosis,Neuronal Ceroid Lipofuscinosis,Ceroid Lipofuscinosis, Neuronal, 10,Disease Of Mental Health,Ceroid Lipofuscinosis, Neuronal, 7,Krabbe Disease,Hurler-Scheie Syndrome,Scheie Syndrome,Mannosidosis, Alpha B, Lysosomal,Metachromatic Leukodystrophy,Ceroid Lipofuscinosis, Neuronal, 3,Mucopolysaccharidosis, Type Ii,Mucopolysaccharidosis, Type Iiia,Mucopolysaccharidosis, Type Iiib,Mucopolysaccharidosis, Type Iiic,Mucopolysaccharidosis, Type Iiid,Mucopolysaccharidosis, Type Iva,Mucopolysaccharidosis, Type Ivb,Mucopolysaccharidosis, Type Vii,Ceroid Lipofuscinosis, Neuronal, 1 |
4mhx_a | P51688 | ENSG00000181523 | SGSH | 99.70 | 4.50E-23 | 2.90E-27 | 203.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | GALNS |
N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) |
3.1.6.4 | Homo sapiens | Bone Development Disease,Zellweger Syndrome,Mucolipidosis,Morquio Syndrome,Gangliosidosis,Osteochondrosis,Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Mucopolysaccharidosis Iv,Multiple Sulfatase Deficiency,Dyggve-Melchior-Clausen Disease,Lysosomal Storage Disease,Tracheal Disease,Isolated Growth Hormone Deficiency, Type Ii,Gm1 Gangliosidosis,Glycoproteinosis,Fucosidosis,Odontochondrodysplasia,Spondyloepiphyseal Dysplasia With Congenital Joint Dislocations,Hurler Syndrome,Hurler-Scheie Syndrome,Scheie Syndrome,Adenine Phosphoribosyltransferase Deficiency,Legg-Calve-Perthes Disease,Mucolipidosis Ii Alpha/Beta,Mucopolysaccharidosis, Type Ii,Mucopolysaccharidosis, Type Iiia,Mucopolysaccharidosis, Type Iiib,Mucopolysaccharidosis, Type Iiic,Mucopolysaccharidosis, Type Iiid,Mucopolysaccharidosis, Type Iva,Mucopolysaccharidosis, Type Ivb,Mucopolysaccharidosis, Type Vi,Mucopolysaccharidosis, Type Vii,Tracheomalacia,Galactosialidosis |
4fdi_a | P34059 | ENSG00000141012 | GALNS | 99.70 | 5.80E-23 | 3.70E-27 | 202.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | IDS SIDS |
Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain] |
3.1.6.13 | Homo sapiens | Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Mucopolysaccharidosis Iv,Sudden Infant Death Syndrome,Tay-Sachs Disease,Lysosomal Storage Disease,Refractory Cytopenia With Multilineage Dysplasia,Gm1-Gangliosidosis, Type Ii,Krabbe Disease,Hurler Syndrome,Epidermolysis Bullosa Simplex With Nail Dystrophy,Scheie Syndrome,Metachromatic Leukodystrophy,Mucopolysaccharidosis, Type Ii,Mucopolysaccharidosis, Type Iiia,Mucopolysaccharidosis, Type Iiib,Mucopolysaccharidosis, Type Iiic,Mucopolysaccharidosis, Type Iiid,Mucopolysaccharidosis, Type Iva,Mucopolysaccharidosis, Type Ivb,Mucopolysaccharidosis, Type Vi,Mucopolysaccharidosis, Type Vii |
5fql_a | P22304 | ENSG00000010404 | IDS | 99.80 | 8.50E-24 | 5.50E-28 | 209.30 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | ARSA |
Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase) [Cleaved into: Arylsulfatase A component B; Arylsulfatase A component C] |
3.1.6.8 | Homo sapiens | Ichthyosis,Mucolipidosis,Gaucher'S Disease,Sphingolipidosis,Dysostosis,Cerebral Palsy,Lipid Storage Disease,Sandhoff Disease,Kleptomania,Mucopolysaccharidosis Iii,Mucopolysaccharidosis-Plus Syndrome,Mucopolysaccharidosis Iv,Canavan Disease,Multiple Sulfatase Deficiency,Hereditary Dystonia,Dementia,Autosomal Recessive Sideroblastic Anemia,Gingival Hypertrophy,Tay-Sachs Disease,Leukodystrophy,Polyneuropathy,Spinocerebellar Ataxia, Autosomal Recessive 14,Metachromatic Leukodystrophy, Adult Form,Metachromatic Leukodystrophy, Late Infantile Form,Metachromatic Leukodystrophy, Juvenile Form,Lysosomal Storage Disease,Demyelinating Disease,Gm2 Gangliosidosis,Gm1 Gangliosidosis,Sneddon Syndrome,Combined Saposin Deficiency,Autosomal Recessive Disease,Krabbe Disease,Fabry Disease,Scheie Syndrome,Metachromatic Leukodystrophy,Mucolipidosis Iii Alpha/Beta,Ceroid Lipofuscinosis, Neuronal, 3,Mucopolysaccharidosis, Type Ii,Mucopolysaccharidosis, Type Iiia,Mucopolysaccharidosis, Type Iva,Mucopolysaccharidosis, Type Vi,Mucopolysaccharidosis, Type Vii,Niemann-Pick Disease, Type C1 |
1n2l_a | P15289 | ENSG00000100299 | ARSA | 99.80 | 1.50E-24 | 9.40E-29 | 213.00 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | Enpp1 Npps Pc1 Pdnp1 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Lymphocyte antigen 41) (Ly-41) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form] [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] |
3.1.4.1,3.6.1.9, | Mus musculus | 4b56_a | P06802 | 100.00 | 8.80E-35 | 5.70E-39 | 303.40 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | betC R00949 SMc00127 |
Choline-sulfatase (EC 3.1.6.6) |
3.1.6.6 | Rhizobium meliloti | 4ug4_b | O69787 | 99.70 | 4.00E-23 | 2.60E-27 | 203.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | ENPP3 PDNP3 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (NPP3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] |
3.1.4.1,3.6.1.9, | Homo sapiens | Egg Allergy,Nut Allergy,Chronic Urticaria,Chronic Inducible Urticaria,Dermatographia,Exercise-Induced Anaphylaxis,Aggressive Systemic Mastocytosis,Allergic Bronchopulmonary Aspergillosis,Food Allergy,Cholinergic Urticaria,Systemic Mastocytosis,Mastocytosis,Urticaria,Wheat Allergy,Cutaneous Solitary Mastocytoma,Amoxicillin Allergy,Cephalosporin Allergy,Chlorhexidine Allergy,Diclofenac Allergy,Carbapenem Allergy,Co-Trimoxazole Allergy,Oxirane Allergy,Scalp-Ear-Nipple Syndrome,Aspergillosis,Hypophosphatasia, Childhood,Arterial Calcification Of Infancy,Physical Urticaria,Respiratory Allergy,Pollen Allergy,Drug Allergy,Fruit Allergy,Apricot Allergy,Peach Allergy,Beta-Lactam Allergy,Crab Allergy,Legume Allergy |
6c01_a | O14638 | ENSG00000154269 | ENPP3 | 100.00 | 9.20E-35 | 5.90E-39 | 303.50 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| YEL016C | NPP2 | SGDID:S000000742 | Arad_4766 |
Arad_4766 |
Agrobacterium radiobacter | 4uph_d | B9JE48 | 99.70 | 1.30E-22 | 8.60E-27 | 201.80 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | phoK |
Alkaline phosphatase PhoK (EC 3.1.3.1) (SPAP protein) |
3.1.3.1 | Sphingomonas sp. | 5xwi_a | A1YYW7 | 99.90 | 5.10E-29 | 3.30E-33 | 249.30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||
| YEL016C | NPP2 | SGDID:S000000742 | PDE |
Venom phosphodiesterase (PDE) (EC 3.6.1.-) |
Naja atra | 5gz4_a | A0A2D0TC04 | 99.90 | 9.50E-33 | 6.10E-37 | 288.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | Chondroitin sulfate/dermatan sulfate 4-O-endosulfatase protein |
Chondroitin sulfate/dermatan sulfate 4-O-endosulfatase protein |
Vibrio | 6j66_a | A0A0C5AQI9 | 99.80 | 2.10E-24 | 1.30E-28 | 214.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| YEL016C | NPP2 | SGDID:S000000742 | DC53_12720 |
DC53_12720 |
Pseudoalteromonas fuliginea | 6b0k_c | A0A063KPH1 | 99.70 | 4.10E-23 | 2.60E-27 | 200.70 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |